在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

S100A14 Antibody

  • 中文名稱:
    S100A14兔多克隆抗體
  • 貨號:
    CSB-PA875728ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA875728ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) S100A14 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    S100A14
  • 別名:
    BCMP84 antibody; Protein S100-A14 antibody; S100 calcium binding protein A14 antibody; S100 calcium-binding protein A14 antibody; S100a14 antibody; S100A15 antibody; S10AE_HUMAN antibody; S114 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein S100-A14 protein (1-104AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
  • 基因功能參考文獻:
    1. S100A14 is expressed in a subset of lung adenocarcinoma, and its expression is related to certain clinicopathological parameters. Furthermore, S100A14 expression was strongly correlated with migration and invasion in lung adenocarcinoma cells. PMID: 28950283
    2. Increased S100A15 expression and decreased DNA methylation of its gene promoter region were associated with high metastasis potential and poor outcome in lung adenocarcinoma. PMID: 28498804
    3. results indicate that S100A14 may have a role in the induction of differentiation and inhibition of cell metastasis in gastric cancer. PMID: 28726786
    4. We identified a two-gene signature including KCNN4 and S100A14 which was related to recurrence in optimally debulked serous ovarian carcinoma patients PMID: 27270322
    5. Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion PMID: 25884418
    6. The antimicrobial peptides psoriasin (S100A7) and koebnerisin (S100A15) suppress extracellular matrix production and proliferation of human fibroblasts PMID: 25502330
    7. S100A14 is expressed in epithelial-like, but not in mesenchymal-like, triple-negative breast cancer cells in vitro. PMID: 25912829
    8. Data show that the genetic variant 425G>A on the 5'-UTR of calcium-binding protein S100A14 was associated with reduced S100A14 expression in gastric cancer (GC) cells. PMID: 25266115
    9. Data indicate that S100A14 has a crucial role in EOC progression, and its overexpression is associated with poor prognosis. PMID: 24939856
    10. Data demonstrate that S100A14 is transcriptionally regulated by JunB and involved in esophageal squamous cell carcinoma cell differentiation. PMID: 24107296
    11. S100A14 interacts with S100A16 and regulates its expression in human cancer cells. PMID: 24086685
    12. Data show that S100A14 and HER2 are colocalized in plasma membrane of breast cancer tissue cells and breast cancer cell lines. PMID: 24285542
    13. High S100A14 expression is associated with metastasis of hepatocellular carcinoma. PMID: 23886191
    14. The solution structure of homodimeric S100A14 in the apo state solved by NMR PMID: 23197251
    15. that S100A14 promotes cell motility and invasiveness by regulating the expression and function of MMP2 in a p53-dependent manner. PMID: 22451655
    16. S100A14 provides a novel role in oral squamous cell carcinoma cell proliferation by inducing G1-arrest PMID: 22032898
    17. S100A14 induces cell apoptosis is partially in a RAGE-dependent manner PMID: 21559403
    18. S100A14 and S100A4 have roles in metastasis in colorectal cancer after surgery PMID: 19956863
    19. Data constitute strong evidence in support of the notion that S100A14 might function as a cancer suppressor working in the P53 pathway and play a role in esophageal carcinogenesis. PMID: 19351828

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    S-100 family
  • 組織特異性:
    Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 18901

    OMIM: 607986

    KEGG: hsa:57402

    STRING: 9606.ENSP00000340463

    UniGene: Hs.288998



主站蜘蛛池模板: 少妇无码av无码专区线| 丰满少妇熟乱xxxxx视频| 精品国产一区二区三区香蕉| 波多野结衣网站| 精品国产乱码久久久久久影片| 欧美巨波霸乳影院| 精品国产乱码久久久久久下载| 曰批全过程免费视频观看软件潮喷| 午夜影视免费x看| 精品欧美一区二区在线观看| 高清欧美性猛交xxxx黑人猛交| 亚洲经典国产精华液单品榜| 2018高清日本一道国产-在 | 国内少妇毛片视频| 亚洲vs日韩vs欧美vs久久| 国产免费午夜福利不卡片在线| 男人添女人下部高潮全视频| 妺妺窝人体色www看美女| 亚洲中文无码人a∨在线导航| av网站的免费观看| 日本肉体裸xxxxbbbb| 沈阳45老熟女高潮喷水亮点| 天堂国产一区二区三区| 无码免费无线观看在线视| 国产又色又爽又黄的在线观看| 无码毛片内射白浆视频| 久久久国产精品亚洲一区| 日日摸日日碰夜夜爽免费| 国产乱人伦偷精精品视频 | 久久av高潮av无码av喷吹| 少妇极品熟妇人妻无码| 日韩国产亚洲欧美中国v| 三个男人躁我一个爽视频免费| 欧美日产国产精品| 午夜无码乱码在线观看| 国产 校园 另类 小说区| 婷婷丁香五月缴情视频| 亚洲字幕av一区二区三区四区| 98视频精品全部国产| 亚洲欧美中文日韩v在线97| 中文字幕乱码人妻无码久久|