在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Prolactin regulatory element-binding protein (PREB), partial

  • 中文名稱:
    人PREB重組蛋白
  • 貨號:
    CSB-YP867205HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PREB重組蛋白
  • 貨號:
    CSB-EP867205HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PREB重組蛋白
  • 貨號:
    CSB-BP867205HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PREB重組蛋白
  • 貨號:
    CSB-MP867205HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Mammalian guanine nucleotide exchange factor mSec12; Preb; PREB_HUMAN; Prolactin regulatory binding element protein; Prolactin regulatory element binding; Prolactin regulatory element binding protein; Prolactin regulatory element-binding protein; SEC12
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.; Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.
  • 基因功能參考文獻:
    1. Administration of recombinant adenovirus containing human PREB to db/db, ob/ob, and DIO mice diminished glucose, insulin, and pyruvate tolerance indicating PREB to be a negative regulator of liver gluconeogenic genes. PMID: 29601978
    2. Wls-SEC12 binding is stable, with the interacting interface biochemically mapped to cytosolic segments of individual proteins. Mutant Wls that fails to communicate with the COPII machinery cannot effectively support Wnt secretion. These data suggest that formation of early Wnt secretory vesicles is carefully regulated to ensure proper export of functional ligands PMID: 28515233
    3. These results indicate that PREB locates at the hepatitis C virus replication complex by interacting with NS4B. PMID: 26739056
    4. Sec12, a guanine-nucleotide exchange factor for Sar1 guanosine triphosphatase, is concentrated at endoplasmic reticulum exit sites and that this concentration of Sec12 is specifically required for the secretion of collagen VII but not other proteins. PMID: 25202031
    5. PREB regulates the cAMP-mediated transcription of the ABCA1 gene in vascular smooth muscle cells PMID: 20643408
    6. The transcriptional factor PREB mediates MCP-1 transcription induced by cytokines in human vascular endothelial cells. PMID: 19426980

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 9356

    OMIM: 606395

    KEGG: hsa:10113

    STRING: 9606.ENSP00000260643

    UniGene: Hs.279784



主站蜘蛛池模板: 丁香啪啪综合成人亚洲| 亚洲男同志网站| 真人做人试看60分钟免费| 西西人体大胆瓣开下部毛茸茸| 人人爽人人爽人人片av| 日韩精品人妻系列一区二区三区| 国内精品乱码卡一卡2卡麻豆| 思思久久精品一本到99热| 国产精品女丝袜白丝袜| 无码无套少妇毛多18pxxxx| 中文字幕无码一区二区免费| 女人爽到高潮潮喷18禁网站| 国产 | 欧洲野花视频欧洲1| 国内高清a自拍视频| 日本丶国产丶欧美色综合| 亚洲熟妇无码一区二区三区| 国产舌乚八伦偷品w中| 亚洲精品久久久一二三区| 337p日本大胆欧久久| 18禁成年无码免费网站| 在线观看人成视频免费| 人人妻人人澡人人爽人人精品av| 高清国产亚洲精品自在久久| 最近中文字幕免费mv在线| 亚洲欧美中文字幕高清在线| 国产午夜精品一区二区三区| 少妇特黄a一区二区三区| 呦男呦女视频精品八区| 亚洲一区天堂九一| 国产亚洲曝欧美不卡精品| 色妺妺在线视频| 成在人线av无码免观看午夜网 | 久久精品国产丝袜人妻| 国产精品无码av无码| 亚洲va在线va天堂va欧美va| 性饥渴少妇av无码毛片| 日韩av影院在线观看| 亚洲va久久久噜噜噜久久4399| 国产人妻xxxx精品hd| 亚洲精品中文字幕| 朝鲜美女黑毛bbw|