在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PREB Antibody

  • 中文名稱:
    PREB兔多克隆抗體
  • 貨號:
    CSB-PA867205LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: Rat liver tissue
      All lanes: PREB antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 46 kDa
      Observed band size: 46 kDa
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA867205LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PREB Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Mammalian guanine nucleotide exchange factor mSec12 antibody; Preb antibody; PREB_HUMAN antibody; Prolactin regulatory binding element protein antibody; Prolactin regulatory element binding antibody; Prolactin regulatory element binding protein antibody; Prolactin regulatory element-binding protein antibody; SEC12 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Rat
  • 免疫原:
    Recombinant Human Prolactin regulatory element-binding protein (98-283AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,PREB Antibody (CSB-PA867205LA01HU),的標記方式是Non-conjugated。對于PREB Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA867205LB01HU PREB Antibody, HRP conjugated ELISA
    FITC CSB-PA867205LC01HU PREB Antibody, FITC conjugated
    Biotin CSB-PA867205LD01HU PREB Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.; Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.
  • 基因功能參考文獻:
    1. Administration of recombinant adenovirus containing human PREB to db/db, ob/ob, and DIO mice diminished glucose, insulin, and pyruvate tolerance indicating PREB to be a negative regulator of liver gluconeogenic genes. PMID: 29601978
    2. Wls-SEC12 binding is stable, with the interacting interface biochemically mapped to cytosolic segments of individual proteins. Mutant Wls that fails to communicate with the COPII machinery cannot effectively support Wnt secretion. These data suggest that formation of early Wnt secretory vesicles is carefully regulated to ensure proper export of functional ligands PMID: 28515233
    3. These results indicate that PREB locates at the hepatitis C virus replication complex by interacting with NS4B. PMID: 26739056
    4. Sec12, a guanine-nucleotide exchange factor for Sar1 guanosine triphosphatase, is concentrated at endoplasmic reticulum exit sites and that this concentration of Sec12 is specifically required for the secretion of collagen VII but not other proteins. PMID: 25202031
    5. PREB regulates the cAMP-mediated transcription of the ABCA1 gene in vascular smooth muscle cells PMID: 20643408
    6. The transcriptional factor PREB mediates MCP-1 transcription induced by cytokines in human vascular endothelial cells. PMID: 19426980

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 9356

    OMIM: 606395

    KEGG: hsa:10113

    STRING: 9606.ENSP00000260643

    UniGene: Hs.279784



主站蜘蛛池模板: 99久久九九社区精品| 女被男啪到哭的视频网站 | 免费裸体无遮挡黄网站免费看| 在线欧美中文字幕农村电影| 4438xx亚洲最大五色丁香| 亚洲精品乱码久久久久久| av天堂中av世界中文在线播放 | 曰韩内射六十七十老熟女影视| 久久伊人色av天堂九九| 精品av国产一二三四区| 国产精品高潮呻吟av久久小说| 十八禁视频在线观看免费无码无遮挡骂过 | 国产成人午夜无码电影在线观看| 国产久久精品| 欧美丰满老熟妇xxxxx性| 永久免费的啪啪网站免费观看| 欲香欲色天天综合久久| 麻豆精品传媒一二三区艾秋| 狠狠cao日日穞夜夜穞av| 亚洲精品第一国产综合亚av| 午夜福利理论片高清在线| 亚洲综合无码av一区二区三区| 亚洲国产欧美在线人成aaaa| 亚洲夜夜性无码| 特黄特级毛片免费视频| 男人天堂2018亚洲男人天堂| 99精品无人区乱码1区2区3区| 黑人强辱丰满的人妻熟女| 国产精品沙发午睡系列990531| 国产超薄肉色丝袜视频| 爆乳护士一区二区三区在线播放| 亚洲精品无码ma在线观看 | 欧美日韩国产精品自在自线| 亚洲精品久久中文字幕| 无码中文字幕av免费放dvd| 强开小婷嫩苞又嫩又紧视频| 久国产精品人妻aⅴ| 久久精品国产只有精品96| 久久精品aⅴ无码中文字字幕蜜桃 午夜成人鲁丝片午夜精品 | 国产精品无码2021在线观看 | 婷婷久久久亚洲欧洲日产国码av|