在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PREB Antibody, FITC conjugated

PREB Antibody, FITC conjugated

  • 中文名稱：
    PREB兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA867205LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PREB Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Mammalian guanine nucleotide exchange factor mSec12 antibody; Preb antibody; PREB_HUMAN antibody; Prolactin regulatory binding element protein antibody; Prolactin regulatory element binding antibody; Prolactin regulatory element binding protein antibody; Prolactin regulatory element-binding protein antibody; SEC12 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Prolactin regulatory element-binding protein (98-283AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.; Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.
  • 基因功能參考文獻：
    1. Administration of recombinant adenovirus containing human PREB to db/db, ob/ob, and DIO mice diminished glucose, insulin, and pyruvate tolerance indicating PREB to be a negative regulator of liver gluconeogenic genes. PMID: 29601978
    2. Wls-SEC12 binding is stable, with the interacting interface biochemically mapped to cytosolic segments of individual proteins. Mutant Wls that fails to communicate with the COPII machinery cannot effectively support Wnt secretion. These data suggest that formation of early Wnt secretory vesicles is carefully regulated to ensure proper export of functional ligands PMID: 28515233
    3. These results indicate that PREB locates at the hepatitis C virus replication complex by interacting with NS4B. PMID: 26739056
    4. Sec12, a guanine-nucleotide exchange factor for Sar1 guanosine triphosphatase, is concentrated at endoplasmic reticulum exit sites and that this concentration of Sec12 is specifically required for the secretion of collagen VII but not other proteins. PMID: 25202031
    5. PREB regulates the cAMP-mediated transcription of the ABCA1 gene in vascular smooth muscle cells PMID: 20643408
    6. The transcriptional factor PREB mediates MCP-1 transcription induced by cytokines in human vascular endothelial cells. PMID: 19426980

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus.
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 9356

    OMIM: 606395

    KEGG: hsa:10113

    STRING: 9606.ENSP00000260643

    UniGene: Hs.279784



主站蜘蛛池模板： 国产v综合v亚洲欧| 国产精品a成v人在线播放| 国产午费午夜福利200集| 欧美色偷偷亚洲天堂bt| 久久精品手机观看| 亚洲国产精品久久精品| 国产内射999视频一区| 西西人体大胆扒开下部337卩| 中文字幕乱码熟妇五十中出色欲| 久久综合给合久久狠狠狠97色 | 亚洲午夜久久久精品影院| 中国女人内谢69xxxx视频| 色婷婷久久综合中文久久一本| 国产精品午夜爆乳美女视频 | 久久婷婷成人综合色综合| 免费萌白酱国产一区二区三区| 天堂在线资源中文在线8| 国产明星裸体xxxx视频| 国产人妻777人伦精品hd| 亚洲精品一区二区| 国产亚洲精品久久久久9999| 产精品视频在线观看免费 | 亚洲bbw性色大片| 十八禁裸体www网站免费观看| 亚洲香蕉视频天天爽| 欧美性猛交xxxx三人| 国产在线精品二区| 波多野结衣的av一区二区三区| 日本两人免费观看的视频| 天天天狠天天碰天天爱| 亚州av综合色区无码一区| 亚洲国产成人久久综合碰| 亚洲国产精品成人影片久久| 九九精品无码专区免费| 免费的很黄很污的视频| 亚洲精品suv精品一区二区| 少妇被多人c夜夜爽爽| 国产精品毛片va一区二区三区 | 少妇精品久久久一区二区三区| 成人免费的视频| 国产精品乱子伦xxxx裸|