在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Probable ATP-dependent RNA helicase DDX20 (DDX20), partial

Recombinant Human Probable ATP-dependent RNA helicase DDX20 (DDX20), partial

  • 中文名稱：
    Recombinant Human Probable ATP-dependent RNA helicase DDX20(DDX20) ,partial
  • 貨號：
    CSB-YP890695HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Probable ATP-dependent RNA helicase DDX20(DDX20) ,partial
  • 貨號：
    CSB-EP890695HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Probable ATP-dependent RNA helicase DDX20(DDX20) ,partial
  • 貨號：
    CSB-EP890695HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Probable ATP-dependent RNA helicase DDX20(DDX20) ,partial
  • 貨號：
    CSB-BP890695HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Probable ATP-dependent RNA helicase DDX20(DDX20) ,partial
  • 貨號：
    CSB-MP890695HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    DDX20
  • Uniprot No.：
  • 別名：
    Component of gems 3; DDX 20; ddx20; DDX20_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD box protein DP103; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 103kD; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20; DEAD/H BOX 20; DKFZP434H052; DP 103; DP103; Gemin-3; Gemin3; Probable ATP dependent RNA helicase DDX20 ; Probable ATP-dependent RNA helicase ddx20; SMN interacting protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
  • 基因功能參考文獻：
    1. The findings show that DDX20 may promote the progression of prostate cancer through the NF-kappaB pathway. PMID: 27121695
    2. In stage-adjusted analysis, the nominal associations of DDX20-rs197412, PTGS2-rs5275, and HSPA5-rs391957 with DFS were detected. However, after FDR correction none of these polymorphisms remained significantly associated with the survival outcomes PMID: 26064972
    3. DP103 defines metastatic potential of human breast cancers. PMID: 25083991
    4. Impairment of miRNA-140 function due to a deficiency of DDX20, a miRNA machinery component, could lead to hepatocarcinogenesis PMID: 22898998
    5. Gemin3 binds with p53, forming a complex, and plays an anti-apoptotic role by repressing the p53 expression in Saos-2 cells. PMID: 22335944
    6. While DDX20 normally suppresses NF-kappaB activity by regulating NF-kappaB-suppressing miRNA-140 function, this suppressive effect was lost in DDX20-deficient cells. PMID: 22445758
    7. we report that EBNA3C directly interacts with Gemin3 through its C-terminal domains PMID: 22174681
    8. NANOS1-PUMILIO2 complex, together with GEMIN3 and small noncoding RNAs, possibly regulate mRNA translation within the chromatoid body of the human germ cells. PMID: 21800163
    9. Data show that the two motor neuropathy-associated mutant HspB8 forms have abnormally increased binding to Ddx20. PMID: 20157854
    10. utilised a targeted screen to identify mRNA associated with SMN, Gemin2 and Gemin3 in the cytoplasm of a human neuroblastoma cell line, SHSY5Y PMID: 20620147
    11. Gemin3 and Gemin4 function in Sm core assembly and correlate the activity of this pathway with Spinal Muscular Atrophy. PMID: 16301532

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus, gem.
  • 蛋白家族：
    DEAD box helicase family, DDX20 subfamily
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2743

    OMIM: 606168

    KEGG: hsa:11218

    STRING: 9606.ENSP00000358716

    UniGene: Hs.591405



主站蜘蛛池模板： 日本乱码伦午夜福利在线| 久久综合亚洲色hezyo国产| 欧美日韩无套内射另类| 欧美精品黑人粗大破除| 亚洲欧美日韩综合久久久久久 | 99热这里只有精品免费播放| 国产内射合集颜射| 蜜桃视频韩日免费播放| 久久精品国产亚洲不av麻豆| 大伊香蕉精品一区视频在线| 色欲久久久天天天综合网精品| 日本两人免费观看的视频| 国产成人午夜精品影院| 一本无码久本草在线中文字幕dvd 337p日本欧洲亚洲大胆裸体艺术 国产av一区二区三区 | 久久精品国产一区二区电影| 两个奶头被吃高潮视频| 午夜无码片在线观看影院| 日产幕无线码三区在线| 720lu国产刺激无码| 中文无码精品一区二区三区| 日本最新免费二区三区| 国产在线精品一区二区夜色| 久久被窝亚洲精品爽爽爽| 下面一进一出好爽视频| 国产精品久久久久影院| 亚洲欧洲自拍拍偷综合| 99精品国产综合久久久久五月天| 影音先锋女人aa鲁色资源| 久久伊人精品波多野结衣| 国产内射在线激情一区| 国产精品久久久久久久久久| 少妇做爰免费视频网站| 国产制服丝袜亚洲高清| 久久精品日韩av无码| 精品无码国产av一区二区| 婷婷丁香六月激情综合在线人| 亚洲精品久久av无码麻| 亚洲性久久久影院| 欧美性开放情侣网站| 国内精品自线在拍2020不卡 | 正在播放酒店约少妇高潮|