在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DDX20 Antibody

DDX20 Antibody

  • 中文名稱：
    DDX20兔多克隆抗體
  • 貨號(hào)：
    CSB-PA006611GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    DDX20
  • 別名：
    Component of gems 3 antibody; DDX 20 antibody; ddx20 antibody; DDX20_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 20 antibody; DEAD box protein 20 antibody; DEAD box protein DP 103 antibody; DEAD box protein DP103 antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 103kD antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 antibody; DEAD/H BOX 20 antibody; DKFZP434H052 antibody; DP 103 antibody; DP103 antibody; Gemin-3 antibody; Gemin3 antibody; Probable ATP dependent RNA helicase DDX20 antibody; Probable ATP-dependent RNA helicase ddx20 antibody; SMN interacting protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human DDX20
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
  • 基因功能參考文獻(xiàn)：
    1. The findings show that DDX20 may promote the progression of prostate cancer through the NF-kappaB pathway. PMID: 27121695
    2. In stage-adjusted analysis, the nominal associations of DDX20-rs197412, PTGS2-rs5275, and HSPA5-rs391957 with DFS were detected. However, after FDR correction none of these polymorphisms remained significantly associated with the survival outcomes PMID: 26064972
    3. DP103 defines metastatic potential of human breast cancers. PMID: 25083991
    4. Impairment of miRNA-140 function due to a deficiency of DDX20, a miRNA machinery component, could lead to hepatocarcinogenesis PMID: 22898998
    5. Gemin3 binds with p53, forming a complex, and plays an anti-apoptotic role by repressing the p53 expression in Saos-2 cells. PMID: 22335944
    6. While DDX20 normally suppresses NF-kappaB activity by regulating NF-kappaB-suppressing miRNA-140 function, this suppressive effect was lost in DDX20-deficient cells. PMID: 22445758
    7. we report that EBNA3C directly interacts with Gemin3 through its C-terminal domains PMID: 22174681
    8. NANOS1-PUMILIO2 complex, together with GEMIN3 and small noncoding RNAs, possibly regulate mRNA translation within the chromatoid body of the human germ cells. PMID: 21800163
    9. Data show that the two motor neuropathy-associated mutant HspB8 forms have abnormally increased binding to Ddx20. PMID: 20157854
    10. utilised a targeted screen to identify mRNA associated with SMN, Gemin2 and Gemin3 in the cytoplasm of a human neuroblastoma cell line, SHSY5Y PMID: 20620147
    11. Gemin3 and Gemin4 function in Sm core assembly and correlate the activity of this pathway with Spinal Muscular Atrophy. PMID: 16301532

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus, gem.
  • 蛋白家族：
    DEAD box helicase family, DDX20 subfamily
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2743

    OMIM: 606168

    KEGG: hsa:11218

    STRING: 9606.ENSP00000358716

    UniGene: Hs.591405



主站蜘蛛池模板： 成人亚洲a片v一区二区三区日本| 荫道bbwbbb高潮潮喷| 又紧又大又爽精品一区二区| 免费大黄网站在线观| 99久久国产精品免费高潮| 成人无码α片在线观看不卡 | 久青草国产在视频在线观看| 国产日产人妻精品精品| www夜片内射视频日韩精品成人| 国产福利萌白酱精品tv一区| 亚洲国产制服丝袜高清在线| 国产偷窥熟女精品视频大全| 99精品久久99久久久久| 日本两人免费观看的视频| 日日日日做夜夜夜夜无码| 丁香啪啪综合成人亚洲| 国产在线拍偷自揄拍无码| 亚洲高请码在线精品av| 国产成人啪精品午夜网站a片免费 国产精品人妻久久久久 | 国产真实乱对白精彩| 久久综合九色综合97婷婷| 亚洲日韩国产中文其他| 中文字幕一区二区三区四区五区 | 人妻精品久久久久中文字幕| 动漫成人无码精品一区二区三区 | 成人试看120秒体验区| 国产精品久久久久久久久人妻| 午夜国产免费视频亚洲| 亚洲最大成人网 色香蕉| 亚洲成av人片在线观看无码| 国产激情久久久久影院老熟女免费| 蜜臀精品国产高清在线观看| 日本又黄又爽gif动态图| 日韩av无码精品人妻系列| 国产爆乳无码视频在线观看| 国产女主播白浆在线看| 国产涩涩视频在线观看| 成人毛片无码免费播放网站| 国内精品久久久久久久影视麻豆| 天天夜碰日日摸日日澡性色av| 在线观看欧美一区二区三区|