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  4. Recombinant Human NKAP-like protein (NKAPL)

Recombinant Human NKAP-like protein (NKAPL)

  • 中文名稱：
    人NKAPL重組蛋白
  • 貨號：
    CSB-YP702797HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人NKAPL重組蛋白
  • 貨號：
    CSB-EP702797HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人NKAPL重組蛋白
  • 貨號：
    CSB-EP702797HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人NKAPL重組蛋白
  • 貨號：
    CSB-BP702797HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人NKAPL重組蛋白
  • 貨號：
    CSB-MP702797HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    NKAPL
  • Uniprot No.：
  • 別名：
    NKAPL; C6orf194; NKAP-like protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-402
  • 氨基酸序列
    MPPVSRSSYS EDIVGSRRRR RSSSGSPPSP QSRCSSWDGC SRSHSRGREG LRPPWSELDV GALYPFSRSG SRGRLPRFRN YAFASSWSTS YSGYRYHRHC YAEERQSAED YEKEESHRQR RLKERERIGE LGAPEVWGPS PKFPQLDSDE HTPVEDEEEV THQKSSSSDS NSEEHRKKKT SRSRNKKKRK NKSSKRKHRK YSDSDSNSES DTNSDSDDDK KRVKAKKKKK KKKHKTKKKK NKKTKKESSD SSCKDSEEDL SEATWMEQPN VADTMDLIGP EAPIIHTSQD EKPLKYGHAL LPGEGAAMAE YVKAGKRIPR RGEIGLTSEE IGSFECSGYV MSGSRHRRME AVRLRKENQI YSADEKRALA SFNQEERRKR ESKILASFRE MVHKKTKEKD DK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis.
  • 基因功能參考文獻：
    1. Single nucleotide polymorphism in NKAPL is associated with atherosclerosis. PMID: 28095483
    2. Overexpression of NKAPL in germline stem cells demonstrated that Nkapl induced changes in spermatogonial stem cell (SSC) markers and the reduction of differentiation factors through the Notch signaling pathway. PMID: 25875095
    3. further evidence for the involvement of NKAPL polymorphisms in the development of schizophrenia. PMID: 26297123
    4. Study suggested that rs1635 in the NKAPL gene appeared to play a role in conferring susceptibility to schizophrenia PMID: 24972756
    5. Fine-mapping analyses identified six NKAPL locus variants in a single haplotype block showing association with rheumatoid arthritis. PMID: 23223422
    6. aFfew qef w wrg egre PMID: 22037552

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    NKAP family
  • 數據庫鏈接：

    HGNC: 21584

    KEGG: hsa:222698

    STRING: 9606.ENSP00000345716

    UniGene: Hs.48787



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