在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Myelin P2 protein (PMP2)

  • 中文名稱:
    人PMP2重組蛋白
  • 貨號:
    CSB-RP078544h
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    PMP2
  • Uniprot No.:
  • 別名:
    FABP8; M FABP; MP2; Myelin FABP ; Myelin P2 protein; MYP2_HUMAN; P2; Peripheral myelin protein 2; PMP2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    41.9kDa
  • 表達區(qū)域:
    1-132aa
  • 氨基酸序列
    MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKNTEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKMKGVVCTRIYEKV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal GST-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
  • 基因功能參考文獻:
    1. The structural characterization of the F57A mutant of P2 which shows changes in the portal region and helix alpha2 and an unfolded status upon lipid bilayer binding. Further results suggest a central role for Phe57 in regulating the opening of the portal region in human P2, and the F57A mutation disturbs dynamic cross-correlation networks in the portal region of P2. PMID: 29940944
    2. SH3TC2, PMP2, and BSCL2 pathogenic variants might be rare in Chinese Charcot-Marie-Tooth (CMT) patients. PMID: 29336362
    3. Our genetic and clinical findings in these kindred demonstrate that dominant PMP2 mutations cause Charcot-Marie- Tooth disease type 1. PMID: 27009151
    4. A fully deuterated sample of myelin P2 protein was produced identifying the neutron crystal structure. PMID: 26527266
    5. This report might expand the genetic and clinical features of Charcot-Marie-Tooth disease and a further mechanism study will enhance our understanding of PMP2-associated peripheral neuropathy. PMID: 26828946
    6. The structure of human P2 refined at the ultrahigh resolution of 0.93 A allows detailed structural analyses, including the full organization of an internal hydrogen-bonding network. PMID: 24419389
    7. the structure and function of the P2 protein from human myelin, which is able to bind both monomeric lipids inside its cavity and membrane surfaces PMID: 20421974

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Calycin superfamily, Fatty-acid binding protein (FABP) family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 9117

    OMIM: 170715

    KEGG: hsa:5375

    STRING: 9606.ENSP00000256103

    UniGene: Hs.571512



主站蜘蛛池模板: 一道本在线伊人蕉无码| 黄网站色视频免费观看| 一二三四视频在线观看日本| 热re99久久6国产精品免费| 国产人妻人伦精品久久久| 国产极品粉嫩福利姬萌白酱| 18禁白丝喷水视频www视频| 色综合久久久久综合体桃花网| 碰超免费人妻中文字幕| 久久九九精品国产av片国产| 午夜福利免费0948视频| 免费观看黄网站在线播放| 俺也来俺也去俺也射| 久久久橹橹橹久久久久高清| 免费做a爰片久久毛片a片下载| 精品一品国产午夜福利视频| 国产精品久久久久9999高清| 国产精品久久久久久妇女| 亚洲成av人在线视猫咪| 自拍偷亚洲产在线观看| 午夜三级a三级三点在线观看| 成人免费区一区二区三区| 精品www日韩熟女人妻| 亚洲精品久久一区二区三区四区| 成人综合网亚洲伊人| 欧美国产日本高清不卡| 国产免费永久精品无码| 色综合久久久久无码专区| 色欲视频综合免费天天| 亚洲无线码免费| 久久无码精品一区二区三区| 国产精品国产三级在线专区| 亚洲va天堂va欧美ⅴa在线 | 大陆精大陆国产国语精品 | 亚洲国产欧美日韩在线人成| 色狠狠av老熟女| 中文字幕亚洲无线码一区女同| 亚洲中文有码字幕青青| 国产无吗一区二区三区在线欢| 97人人模人人爽人人少妇| 日韩欧美中文字幕在线三区 |