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PMP2 Antibody

  • 中文名稱:
    PMP2兔多克隆抗體
  • 貨號:
    CSB-PA07854A0Rb
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: PMP2 antibody at 2µg/ml + EC109 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/15000 dilution
      Predicted band size: 15 kDa
      Observed band size: 15 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PMP2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PMP2
  • 別名:
    FABP8 antibody; M FABP antibody; MP2 antibody; Myelin FABP antibody; Myelin P2 protein antibody; MYP2_HUMAN antibody; P2 antibody; Peripheral myelin protein 2 antibody; PMP2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Myelin P2 protein (1-132AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,PMP2 Antibody (CSB-PA07854A0Rb),的標記方式是Non-conjugated。對于PMP2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA07854B0Rb PMP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA07854C0Rb PMP2 Antibody, FITC conjugated
    Biotin CSB-PA07854D0Rb PMP2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
  • 基因功能參考文獻:
    1. The structural characterization of the F57A mutant of P2 which shows changes in the portal region and helix alpha2 and an unfolded status upon lipid bilayer binding. Further results suggest a central role for Phe57 in regulating the opening of the portal region in human P2, and the F57A mutation disturbs dynamic cross-correlation networks in the portal region of P2. PMID: 29940944
    2. SH3TC2, PMP2, and BSCL2 pathogenic variants might be rare in Chinese Charcot-Marie-Tooth (CMT) patients. PMID: 29336362
    3. Our genetic and clinical findings in these kindred demonstrate that dominant PMP2 mutations cause Charcot-Marie- Tooth disease type 1. PMID: 27009151
    4. A fully deuterated sample of myelin P2 protein was produced identifying the neutron crystal structure. PMID: 26527266
    5. This report might expand the genetic and clinical features of Charcot-Marie-Tooth disease and a further mechanism study will enhance our understanding of PMP2-associated peripheral neuropathy. PMID: 26828946
    6. The structure of human P2 refined at the ultrahigh resolution of 0.93 A allows detailed structural analyses, including the full organization of an internal hydrogen-bonding network. PMID: 24419389
    7. the structure and function of the P2 protein from human myelin, which is able to bind both monomeric lipids inside its cavity and membrane surfaces PMID: 20421974

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  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Calycin superfamily, Fatty-acid binding protein (FABP) family
  • 數據庫鏈接:

    HGNC: 9117

    OMIM: 170715

    KEGG: hsa:5375

    STRING: 9606.ENSP00000256103

    UniGene: Hs.571512



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