Human Myelin P2 protein (PMP2) ELISA kit
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中文名稱:人髓磷脂P2蛋白(PMP2)酶聯免疫試劑盒
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貨號:CSB-E09601h
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規格:96T/48T
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價格:¥3600/¥2500
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其他:
產品詳情
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產品描述:人髓磷脂P2蛋白(PMP2)酶聯免疫試劑盒(CSB-E09601h)檢測樣本中的PMP2含量。本試劑盒適用于多種生物樣本的檢測(具體適用樣本類型需根據實驗需求確認);可滿足基礎科研中PMP2蛋白表達水平分析、疾病模型機制探究以及藥物干預效果評估等需求,例如在吉蘭 - 巴雷綜合征、Charcot - Marie - Tooth病等神經病變研究中的應用。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
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別名:FABP8 ELISA Kit; M FABP ELISA Kit; MP2 ELISA Kit; Myelin FABP ELISA Kit; Myelin P2 protein ELISA Kit; MYP2_HUMAN ELISA Kit; P2 ELISA Kit; Peripheral myelin protein 2 ELISA Kit; PMP2 ELISA Kit
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縮寫:PMP2
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Uniprot No.:
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種屬:Homo sapiens (Human)
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檢測范圍:Request Information
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靈敏度:Request Information
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Cardiovascular
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貨期:3-5 working days
相關產品
靶點詳情
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功能:May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
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基因功能參考文獻:
- The structural characterization of the F57A mutant of P2 which shows changes in the portal region and helix alpha2 and an unfolded status upon lipid bilayer binding. Further results suggest a central role for Phe57 in regulating the opening of the portal region in human P2, and the F57A mutation disturbs dynamic cross-correlation networks in the portal region of P2. PMID: 29940944
- SH3TC2, PMP2, and BSCL2 pathogenic variants might be rare in Chinese Charcot-Marie-Tooth (CMT) patients. PMID: 29336362
- Our genetic and clinical findings in these kindred demonstrate that dominant PMP2 mutations cause Charcot-Marie- Tooth disease type 1. PMID: 27009151
- A fully deuterated sample of myelin P2 protein was produced identifying the neutron crystal structure. PMID: 26527266
- This report might expand the genetic and clinical features of Charcot-Marie-Tooth disease and a further mechanism study will enhance our understanding of PMP2-associated peripheral neuropathy. PMID: 26828946
- The structure of human P2 refined at the ultrahigh resolution of 0.93 A allows detailed structural analyses, including the full organization of an internal hydrogen-bonding network. PMID: 24419389
- the structure and function of the P2 protein from human myelin, which is able to bind both monomeric lipids inside its cavity and membrane surfaces PMID: 20421974
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亞細胞定位:Cytoplasm.
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蛋白家族:Calycin superfamily, Fatty-acid binding protein (FABP) family
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數據庫鏈接:
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