在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Leucine zipper transcription factor-like protein 1 (LZTFL1)

  • 中文名稱:
    人LZTFL1重組蛋白
  • 貨號:
    CSB-YP885687HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人LZTFL1重組蛋白
  • 貨號:
    CSB-EP885687HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人LZTFL1重組蛋白
  • 貨號:
    CSB-EP885687HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人LZTFL1重組蛋白
  • 貨號:
    CSB-BP885687HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人LZTFL1重組蛋白
  • 貨號:
    CSB-MP885687HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    LZTFL1
  • Uniprot No.:
  • 別名:
    5530402H04Rik; 6130400H19Rik; AI414725; AW048545; BBS17; DKFZp686H2076; FLJ36386; Leucine zipper transcription factor like 1; Leucine zipper transcription factor like protein 1; Leucine zipper transcription factor-like protein 1; LZTFL 1; Lztfl1; Lztfl1 leucine zipper transcription factor-like 1; LZTL1_HUMAN; MGC106871; MGC108960; Putative uncharacterized protein DKFZp686H2076
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-299
  • 氨基酸序列
    MAELGLNEHH QNEVINYMRF ARSKRGLRLK TVDSCFQDLK ESRLVEDTFT IDEVSEVLNG LQAVVHSEVE SELINTAYTN VLLLRQLFAQ AEKWYLKLQT DISELENREL LEQVAEFEKA EITSSNKKPI LDVTKPKLAP LNEGGTAELL NKEILRLQEE NEKLKSRLKT IEIQATNALD EKSKLEKALQ DLQLDQGNQK DFIKAQDLSN LENTVAALKS EFQKTLNDKT ENQKSLEENL ATAKHDLLRV QEQLHMAEKE LEKKFQQTAA YRNMKEILTK KNDQIKDLRK RLAQYEPED
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
  • 基因功能參考文獻:
    1. LZTFL1 inhibits lung tumorigenesis PMID: 26364604
    2. these data indicate that LZTFL1 modulates T cell activation and IL-5 levels. PMID: 26700766
    3. LZTFL1 binds beta-catenin in the cytoplasm of the cell and inhibited its nuclear translocation PMID: 25005785
    4. This special subtype of polydactyly in BBS patients is easily identified on clinical examination and prompts for priority sequencing of LZTFL1 (BBS17). PMID: 23692385
    5. The absence of LZTFL1 leads to a BBS phenotype with enhanced developmental abnormalities associated with cellular Shh dysfunction. LZTFL1 is a novel BBS gene (BBS17). PMID: 22510444
    6. Our findings suggest that LZTFL1 is an important regulator of BBSome ciliary trafficking and hedgehog signaling PMID: 22072986
    7. LZTFL1 may inhibit tumorigenesis by stabilizing E-cadherin-mediated adherens junction formation and promoting epithelial cell differentiation. PMID: 20233871

    顯示更多

    收起更多

  • 相關疾病:
    Bardet-Biedl syndrome 17 (BBS17)
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    LZTFL1 family
  • 組織特異性:
    Expressed in prostate, ovary, stomach, pancreas, esophagus, breast, liver, bladder, kidney, thyroid, colon and lung (at protein level). Down-regulated in multiple primary tumors (at protein level). Detected in testis, heart, skeletal muscle, thymus, splee
  • 數據庫鏈接:

    HGNC: 6741

    OMIM: 606568

    KEGG: hsa:54585

    STRING: 9606.ENSP00000296135

    UniGene: Hs.30824



主站蜘蛛池模板: 国产香蕉尹人在线观看视频 | 国产午夜精品一区理论片飘花| 国产伦理一区二区| 国产麻豆精品一区二区三区v视界| 九九九国产精品成人免费视频| 国产一区二区三区在线视頻| 国产成人精品自在线拍| 熟女少妇人妻中文字幕| 亚洲欧洲免费无码| 久久亚洲精品国产精品777777| 免费无码午夜福利片69| 色琪琪av中文字幕一区二区| 国产女人18毛片水真多| 天堂а√在线中文在线新版 | 超碰97人人射妻| 波多野42部无码喷潮| 日本久久综合久久综合| 2021在线不卡国产麻豆| 久久婷婷成人综合色综合| 日韩视频在线观看| 性欧美俄罗斯极品| 国产剧情无码播放在线看| 五月丁香六月综合av | 成人国产精品无码网站| 欧美性大战xxxxx久久久√| 久久综合九色综合网站| 亚洲国产精品18久久久久久| 激情综合婷婷丁香五月情| 精品av综合导航| 竹菊影视欧美日韩一区二区三区四区五区 | 熟妇人妻中文字幕| 日韩av在线观看免费| 亚洲另类欧美在线电影| 精品国产乱码一区二区三区| 日韩人妻一区二区三区免费| 久久综合九色综合97婷婷| 中文字幕奈奈美被公侵犯| 国产精品女视频一区二区| 色丁香婷婷综合久久| 2020最新国产高清毛片 | 久久久精品人妻一区二区三区蜜桃 |