在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Lanosterol synthase (LSS)

In Stock
  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-EP013216HU
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    LSS
  • Uniprot No.:
  • 別名:
    2,3-epoxysqualene--lanosterol cyclase Oxidosqualene--lanosterol cyclase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    89.2 kDa
  • 表達區域:
    2-732aa
  • 氨基酸序列
    TEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDTKNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLPAGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
  • 基因功能參考文獻:
    1. LSS gene mutation is associated with Congenital cataract. PMID: 29016354
    2. Lanosterol synthase gene polymorphisms influence both the salt sensitivity of BP and changes in circulating EO in response to a low salt diet. PMID: 26667413
    3. There were no significant differences in OSC mRNA expression at various stages of breast cancer, or between tumor and normal mammary cells. PMID: 25051231
    4. oxidosqualene cyclase is active as a monomer PMID: 14766201
    5. two crystal structures of the human membrane protein OSC: the target protein with an inhibitor that showed cholesterol lowering in vivo opens the way for the structure-based design of new OSC inhibitors PMID: 15525992
    6. Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile. PMID: 19119143

    顯示更多

    收起更多

  • 相關疾病:
    Cataract 44 (CTRCT44)
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Peripheral membrane protein.
  • 蛋白家族:
    Terpene cyclase/mutase family
  • 組織特異性:
    Widely expressed. Expressed in the hair bulb, the outer root sheath and hair matrix of the hair follicle epithelium. Also detected in dermal papilla, epidermis, sweat glands, sebaceous glands, and blood vessels.
  • 數據庫鏈接:

    HGNC: 6708

    OMIM: 600909

    KEGG: hsa:4047

    STRING: 9606.ENSP00000348762

    UniGene: Hs.596543



主站蜘蛛池模板: 搡老女人老妇女老熟妇| 亚洲人成人无码网www电影首页| 无码gogo大胆啪啪艺术| 亚洲色无码播放| 51被公侵犯玩弄漂亮人妻| 一区二区三区无码被窝影院| 亚洲精品久久久久午夜福利| 亚洲国产成人久久综合同性 | 亚洲国产欧美日韩精品一区二区三区| 日韩精品无码一区二区| 人妻丰满熟妇aⅴ无码| 欧美巨大xxxx做受中文字幕| 无码h肉动漫在线观看免费| 全黄激性性视频| 搡老熟女国产| 久久综合国产乱子伦精品免费| 久久天天躁狠狠躁夜夜av浪潮| 久热这里只有精品视频6| 久久99国产亚洲高清观看首页| 精品香蕉99久久久久网站| 男女啪啦猛视频免费| 国产毛片一区二区精品| 日韩av无码成人无码免费| 人妻熟女一区二区aⅴ林晓雪| 77777_亚洲午夜久久多人| 永久免费观看美女裸体视频的网站| 国产传媒麻豆剧精品av国产| 人妻免费一区二区三区最新| 亚洲日韩成人av无码网站| 内射人妻少妇无码一本一道| 国内午夜熟妇又乱又伦| 国产美女口爆吞精普通话| 亚洲中文字幕日产无码成人片| 人人妻在人人| 国内最真实的xxxx人伦| 人妻体内射精一区二区三四| 乱码精品一区二区三区| 国产午夜a理论毛片| 亚洲国产成人av人片久久| 久久99精品久久久久婷婷 | 国产片a国产片免费看视频|