在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Lanosterol synthase (LSS)

  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-YP013216HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-EP013216HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-BP013216HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-MP013216HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    LSS
  • Uniprot No.:
  • 別名:
    LSS; OSCLanosterol synthase; EC 5.4.99.7; 2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; OSC; hOSC
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-732
  • 氨基酸序列
    TEGTCLRRR GGPYKTEPAT DLGRWRLNCE RGRQTWTYLQ DERAGREQTG LEAYALGLDT KNYFKDLPKA HTAFEGALNG MTFYVGLQAE DGHWTGDYGG PLFLLPGLLI TCHVARIPLP AGYREEIVRY LRSVQLPDGG WGLHIEDKST VFGTALNYVS LRILGVGPDD PDLVRARNIL HKKGGAVAIP SWGKFWLAVL NVYSWEGLNT LFPEMWLFPD WAPAHPSTLW CHCRQVYLPM SYCYAVRLSA AEDPLVQSLR QELYVEDFAS IDWLAQRNNV APDELYTPHS WLLRVVYALL NLYEHHHSAH LRQRAVQKLY EHIVADDRFT KSISIGPISK TINMLVRWYV DGPASTAFQE HVSRIPDYLW MGLDGMKMQG TNGSQIWDTA FAIQALLEAG GHHRPEFSSC LQKAHEFLRL SQVPDNPPDY QKYYRQMRKG GFSFSTLDCG WIVSDCTAEA LKAVLLLQEK CPHVTEHIPR ERLCDAVAVL LNMRNPDGGF ATYETKRGGH LLELLNPSEV FGDIMIDYTY VECTSAVMQA LKYFHKRFPE HRAAEIRETL TQGLEFCRRQ QRADGSWEGS WGVCFTYGTW FGLEAFACMG QTYRDGTACA EVSRACDFLL SRQMADGGWG EDFESCEERR YLQSAQSQIH NTCWAMMGLM AVRHPDIEAQ ERGVRCLLEK QLPNGDWPQE NIAGVFNKSC AISYTSYRNI FPIWALGRFS QLYPERALAG HP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
  • 基因功能參考文獻:
    1. LSS gene mutation is associated with Congenital cataract. PMID: 29016354
    2. Lanosterol synthase gene polymorphisms influence both the salt sensitivity of BP and changes in circulating EO in response to a low salt diet. PMID: 26667413
    3. There were no significant differences in OSC mRNA expression at various stages of breast cancer, or between tumor and normal mammary cells. PMID: 25051231
    4. oxidosqualene cyclase is active as a monomer PMID: 14766201
    5. two crystal structures of the human membrane protein OSC: the target protein with an inhibitor that showed cholesterol lowering in vivo opens the way for the structure-based design of new OSC inhibitors PMID: 15525992
    6. Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile. PMID: 19119143

    顯示更多

    收起更多

  • 相關疾病:
    Cataract 44 (CTRCT44)
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Peripheral membrane protein.
  • 蛋白家族:
    Terpene cyclase/mutase family
  • 組織特異性:
    Widely expressed. Expressed in the hair bulb, the outer root sheath and hair matrix of the hair follicle epithelium. Also detected in dermal papilla, epidermis, sweat glands, sebaceous glands, and blood vessels.
  • 數據庫鏈接:

    HGNC: 6708

    OMIM: 600909

    KEGG: hsa:4047

    STRING: 9606.ENSP00000348762

    UniGene: Hs.596543



主站蜘蛛池模板: 国产精品国产三级国产普通话| 国产成人一区二区三区免费视频| 欧美巨大xxxx做受中文字幕 | 午夜福利视频极品国产83| 国产孩cao大人xxxx| 果冻传媒亚洲区二期| 国产精品美女久久久| 天堂网在线最新版www资源网| 久久精品亚洲精品国产色婷| 狠狠色噜噜狠狠狠狠米奇777| 亚洲一区二区三区国产精品无码| 国产 | 久你欧洲野花视频欧洲1| 欧美成人一区二区三区| 女人被狂c到高潮视频网站| 免费人成视频在线播放视频| 草草浮力地址线路①屁屁影院| 国偷自产av一区二区三区| 一本色道av久久精品+网站| 国产精品午夜爆乳美女视频 | 国产95在线 | 亚洲| 一本大道av伊人久久综合| 无码人妻久久一区二区三区不卡 | 久久伊人五月丁香狠狠色| 色综合天天视频在线观看| 久久亚洲精品无码av宋| 女女女女女裸体处开bbb| 国产婷婷丁香五月缴情成人网| 成人免费无码大片a毛片抽搐| 久9re热视频这里只有精品| 掀开奶罩边吃边摸下娇喘视频| 邪恶肉肉全彩色无遮盖| 中文字幕亚洲欧美日韩在线不卡 | 西西人体大胆瓣开下部毛茸茸| 私人家庭影院5777| 欧洲美女粗暴牲交免费观看| 在线 | 一区二区三区| 99在线 | 亚洲| 亚洲国产欧美在线人成| 人妻无码久久久久久久久久久| 妺妺窝人体色777777| 日产精品一卡2卡三卡4乱码|