在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Lanosterol synthase (LSS)

  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-YP013216HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-EP013216HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-BP013216HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人LSS重組蛋白
  • 貨號:
    CSB-MP013216HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    LSS
  • Uniprot No.:
  • 別名:
    LSS; OSCLanosterol synthase; EC 5.4.99.7; 2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; OSC; hOSC
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-732
  • 氨基酸序列
    TEGTCLRRR GGPYKTEPAT DLGRWRLNCE RGRQTWTYLQ DERAGREQTG LEAYALGLDT KNYFKDLPKA HTAFEGALNG MTFYVGLQAE DGHWTGDYGG PLFLLPGLLI TCHVARIPLP AGYREEIVRY LRSVQLPDGG WGLHIEDKST VFGTALNYVS LRILGVGPDD PDLVRARNIL HKKGGAVAIP SWGKFWLAVL NVYSWEGLNT LFPEMWLFPD WAPAHPSTLW CHCRQVYLPM SYCYAVRLSA AEDPLVQSLR QELYVEDFAS IDWLAQRNNV APDELYTPHS WLLRVVYALL NLYEHHHSAH LRQRAVQKLY EHIVADDRFT KSISIGPISK TINMLVRWYV DGPASTAFQE HVSRIPDYLW MGLDGMKMQG TNGSQIWDTA FAIQALLEAG GHHRPEFSSC LQKAHEFLRL SQVPDNPPDY QKYYRQMRKG GFSFSTLDCG WIVSDCTAEA LKAVLLLQEK CPHVTEHIPR ERLCDAVAVL LNMRNPDGGF ATYETKRGGH LLELLNPSEV FGDIMIDYTY VECTSAVMQA LKYFHKRFPE HRAAEIRETL TQGLEFCRRQ QRADGSWEGS WGVCFTYGTW FGLEAFACMG QTYRDGTACA EVSRACDFLL SRQMADGGWG EDFESCEERR YLQSAQSQIH NTCWAMMGLM AVRHPDIEAQ ERGVRCLLEK QLPNGDWPQE NIAGVFNKSC AISYTSYRNI FPIWALGRFS QLYPERALAG HP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
  • 基因功能參考文獻:
    1. LSS gene mutation is associated with Congenital cataract. PMID: 29016354
    2. Lanosterol synthase gene polymorphisms influence both the salt sensitivity of BP and changes in circulating EO in response to a low salt diet. PMID: 26667413
    3. There were no significant differences in OSC mRNA expression at various stages of breast cancer, or between tumor and normal mammary cells. PMID: 25051231
    4. oxidosqualene cyclase is active as a monomer PMID: 14766201
    5. two crystal structures of the human membrane protein OSC: the target protein with an inhibitor that showed cholesterol lowering in vivo opens the way for the structure-based design of new OSC inhibitors PMID: 15525992
    6. Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile. PMID: 19119143

    顯示更多

    收起更多

  • 相關疾病:
    Cataract 44 (CTRCT44)
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Peripheral membrane protein.
  • 蛋白家族:
    Terpene cyclase/mutase family
  • 組織特異性:
    Widely expressed. Expressed in the hair bulb, the outer root sheath and hair matrix of the hair follicle epithelium. Also detected in dermal papilla, epidermis, sweat glands, sebaceous glands, and blood vessels.
  • 數據庫鏈接:

    HGNC: 6708

    OMIM: 600909

    KEGG: hsa:4047

    STRING: 9606.ENSP00000348762

    UniGene: Hs.596543



主站蜘蛛池模板: 久久人人97超碰超国产| 欧美老熟妇乱大交xxxxx| 天堂中文在线资源| 日韩在线视频线观看一区| 日韩 高清 无码 人妻| 亚洲日韩av无码| 国产精品久久久av久久久| 女人喷水高潮时的视频网站 | 国语自产精品视频在 视频| 中文无码日韩欧免费视频| 午夜亚洲www湿好爽| 熟女俱乐部五十路六十路av| 狠狠久久精品中文字幕无码| 精品国产卡一卡2卡3卡| 成年男女免费视频网站| 51视频国产精品一区二区| 热99re久久精品国产首页免费| 欧美40老熟妇色xxxxx| 国产一精品一av一免费| 无码精品国产一区二区三区免费| 国产99青草视频在线播放视| 涩涩鲁亚洲精品一区二区| 欧洲乱码伦视频免费| 男女免费观看做爰视频在线观看| 一二三四观看视频社区在线| 精品久久久久久久中文字幕| 99国产精品国产精品九九| 无码人妻aⅴ一区二区三区玉蒲团| 亚洲精品国产一二三无码av| 精品成人av一区二区三区| 白嫩日本少妇做爰| 337p日本大胆欧久久| 在线播放国产精品三级| 18禁裸男晨勃露j毛免费观看| 亚洲伊人久久综合成人| 日本xxxx18野外无毒不卡| 爆乳女仆高潮在线观看| 亚洲人成电影网站色| 激烈的性高湖波多野结衣| 久久精品国产亚洲7777| 精品无码一区二区三区爱欲|