在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Glycogen phosphorylase, brain form (PYGB), partial

Recombinant Human Glycogen phosphorylase, brain form (PYGB), partial

  • 中文名稱：
    人PYGB重組蛋白
  • 貨號：
    CSB-YP019120HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PYGB重組蛋白
  • 貨號：
    CSB-EP019120HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PYGB重組蛋白
  • 貨號：
    CSB-EP019120HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PYGB重組蛋白
  • 貨號：
    CSB-BP019120HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PYGB重組蛋白
  • 貨號：
    CSB-MP019120HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Brain glycogen phosphorylase; Glycogen phosphorylase B; Glycogen phosphorylase brain form; Glycogen Phosphorylase Isoenzyme BB; Glycogen phosphorylase; brain form; MGC9213; Phosphorylase glycogen brain; PYGB; PYGB_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  • 基因功能參考文獻(xiàn)：
    1. PYGB siRNA exerted an inhibitory effect on the cell viability of the human osteosarcoma cells MG63 and HOS by blocking the Caspase/Bcl and CDK1 signaling pathway, highlighting novel potential therapeutic methods for treating osteosarcoma. PMID: 29845265
    2. Using cysteine chemical labeling, mass spectrometry, and site-directed mutagenesis approaches, we show that thiram (and certain of its metabolites) alters the activity of bGP through the formation of an intramolecular disulfide bond (Cys(318)-Cys(326)), known to act as a redox switch that precludes the allosteric activation of bGP by AMP. PMID: 27965358
    3. disulfide bond acts as a redox switch that precludes the allosteric activation of the enzyme by AMP without affecting its activation by phosphorylation. This unique regulatory feature of bGP sheds new light on the isoform-specific regulation of glycogen phosphorylase and glycogen metabolism. PMID: 27660393
    4. the bGP structures reveal molecular features unique to the brain isozyme that provide a deeper understanding of the differences in the activation properties of these allosteric enzymes by the allosteric effector AMP. PMID: 27402852
    5. GPBB is a valuable biological marker to predict the prognosis in patient with acute coronary syndrome. PMID: 22818785
    6. H-FABP and GPBB can contribute to early acute myocardial infarction diagnosis and can distinguish acute myocardial infarction from acute coronary syndrome PMID: 22838188
    7. Significant increase in plasma glycoprotein BB in patients with hypertrophic cardiomyopathy. PMID: 20482380
    8. Brain-type glycogen phosphorylase is expressed in non-small-cell lung carcinoma, particularly adenocarcinomas, and is an independent poor prognostic factor. PMID: 17393985

    顯示更多

    收起更多

  • 蛋白家族：
    Glycogen phosphorylase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9723

    OMIM: 138550

    KEGG: hsa:5834

    STRING: 9606.ENSP00000216962

    UniGene: Hs.368157



主站蜘蛛池模板： 男女性杂交内射妇女bbwxz| 1000部夫妻午夜免费| 国产麻豆成人传媒免费观看| 亚洲老妇色熟女老太| 又黄又爽又色的视频| 亚洲日韩穿丝袜在线推荐| 美国人性欧美xxxx| 欧洲熟妇精品视频| 欧美3p两根一起进高清免费视频| 精品亚洲成a人在线观看青青| 五 月 丁 香 综合中文| 久久综合九色综合网站| 国产成人精品高清在线观看99| 国产又黄又潮娇喘视频在线观看| 亚洲成成熟女人专区| 中国妇女做爰视频| 国产女人爽的流水毛片| 日本高清中文字幕免费一区二区 | 国产精品 欧美 亚洲 制服| 麻豆高清免费国产一区| 国产在线一区二区av视频| 人妻精品久久无码区| 艳妇荡女欲乱双飞两中年熟妇| 色爽黄1000部免费软件下载| 强插女教师av在线| 欧美人与动牲交欧美精品| 久久久噜噜噜www成人网| 西西人体做爰大胆gogo| 亚洲国产成人精品无码区在线软件 | 99久e在线精品视频在线| 特黄特色大片免费播放器图片| 小雪尝禁果又粗又大的视频| 五月综合色婷婷在线观看| 男人靠女人的免费视频| 乱熟女高潮一区二区在线| 成人爽a毛片免费网站| 老子影院午夜伦不卡无码| 99久久久无码国产精品6 | 十八禁视频网站在线观看| 天天影视网天天综合色| 无码中文字幕乱在线观看|