在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PYGB Antibody, HRP conjugated

  • 中文名稱:
    PYGB兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA10065B0Rb
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PYGB Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Brain glycogen phosphorylase antibody; Glycogen phosphorylase B antibody; Glycogen phosphorylase brain form antibody; Glycogen Phosphorylase Isoenzyme BB antibody; Glycogen phosphorylase; brain form antibody; MGC9213 antibody; Phosphorylase glycogen brain antibody; PYGB antibody; PYGB_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Glycogen phosphorylase, brain form protein (6-843AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  • 基因功能參考文獻:
    1. PYGB siRNA exerted an inhibitory effect on the cell viability of the human osteosarcoma cells MG63 and HOS by blocking the Caspase/Bcl and CDK1 signaling pathway, highlighting novel potential therapeutic methods for treating osteosarcoma. PMID: 29845265
    2. Using cysteine chemical labeling, mass spectrometry, and site-directed mutagenesis approaches, we show that thiram (and certain of its metabolites) alters the activity of bGP through the formation of an intramolecular disulfide bond (Cys(318)-Cys(326)), known to act as a redox switch that precludes the allosteric activation of bGP by AMP. PMID: 27965358
    3. disulfide bond acts as a redox switch that precludes the allosteric activation of the enzyme by AMP without affecting its activation by phosphorylation. This unique regulatory feature of bGP sheds new light on the isoform-specific regulation of glycogen phosphorylase and glycogen metabolism. PMID: 27660393
    4. the bGP structures reveal molecular features unique to the brain isozyme that provide a deeper understanding of the differences in the activation properties of these allosteric enzymes by the allosteric effector AMP. PMID: 27402852
    5. GPBB is a valuable biological marker to predict the prognosis in patient with acute coronary syndrome. PMID: 22818785
    6. H-FABP and GPBB can contribute to early acute myocardial infarction diagnosis and can distinguish acute myocardial infarction from acute coronary syndrome PMID: 22838188
    7. Significant increase in plasma glycoprotein BB in patients with hypertrophic cardiomyopathy. PMID: 20482380
    8. Brain-type glycogen phosphorylase is expressed in non-small-cell lung carcinoma, particularly adenocarcinomas, and is an independent poor prognostic factor. PMID: 17393985

    顯示更多

    收起更多

  • 蛋白家族:
    Glycogen phosphorylase family
  • 數據庫鏈接:

    HGNC: 9723

    OMIM: 138550

    KEGG: hsa:5834

    STRING: 9606.ENSP00000216962

    UniGene: Hs.368157



主站蜘蛛池模板: 超碰国产精品久久国产精品99 | 曰韩内射六十七十老熟女影视 | 男女超爽视频免费播放| 99久久无码一区人妻a片蜜| 国产成人高清精品免费| 国产午夜无码片在线观看网站| 日本肉体裸xxxxbbbb| 国产精品永久在线观看| 精品少妇人妻av无码久久| 亚洲成a人片在线观看无码下载| 午夜亚洲乱码伦小说区69堂| 日韩无套内射视频6| 国产97人妻人人做人碰人人爽| 亚洲色成人影院在线观看| 久久无码专区国产精品| 试看120分钟做受小视频| 99久久国产宗和精品1上映| 色噜噜狠狼综合在线| 日韩av毛片无码免费| 国产98在线 | 欧美| 久久久亚洲一区二区三区| 欧美破苞系列二十三| 成年无码动漫av片在线尤物| 伊人久久大香线蕉aⅴ色| 久久精品无码av| 欧美va亚洲va在线观看| 久久九九久精品国产| 国产成人高清精品免费| 亚洲欧美日韩v在线观看不卡| av无码一区二区三区| 久久精品国产99国产精偷| 西西人体大胆无码视频| 波多野结衣一区二区三区av免费| 国产中文字字幕乱码无限 | 国产黄a三级三级三级av在线看| 亚洲国产精品不卡av在线| 中老年熟妇激情啪啪大屁股| 午夜福利92国语| 国产综合在线观看| 国产成人片无码免费视频| 牛和人交videos欧美|