在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PYGB Antibody

  • 中文名稱:
    PYGB兔多克隆抗體
  • 貨號:
    CSB-PA019120GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Brain glycogen phosphorylase antibody; Glycogen phosphorylase B antibody; Glycogen phosphorylase brain form antibody; Glycogen Phosphorylase Isoenzyme BB antibody; Glycogen phosphorylase; brain form antibody; MGC9213 antibody; Phosphorylase glycogen brain antibody; PYGB antibody; PYGB_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human PYGB
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  • 基因功能參考文獻:
    1. PYGB siRNA exerted an inhibitory effect on the cell viability of the human osteosarcoma cells MG63 and HOS by blocking the Caspase/Bcl and CDK1 signaling pathway, highlighting novel potential therapeutic methods for treating osteosarcoma. PMID: 29845265
    2. Using cysteine chemical labeling, mass spectrometry, and site-directed mutagenesis approaches, we show that thiram (and certain of its metabolites) alters the activity of bGP through the formation of an intramolecular disulfide bond (Cys(318)-Cys(326)), known to act as a redox switch that precludes the allosteric activation of bGP by AMP. PMID: 27965358
    3. disulfide bond acts as a redox switch that precludes the allosteric activation of the enzyme by AMP without affecting its activation by phosphorylation. This unique regulatory feature of bGP sheds new light on the isoform-specific regulation of glycogen phosphorylase and glycogen metabolism. PMID: 27660393
    4. the bGP structures reveal molecular features unique to the brain isozyme that provide a deeper understanding of the differences in the activation properties of these allosteric enzymes by the allosteric effector AMP. PMID: 27402852
    5. GPBB is a valuable biological marker to predict the prognosis in patient with acute coronary syndrome. PMID: 22818785
    6. H-FABP and GPBB can contribute to early acute myocardial infarction diagnosis and can distinguish acute myocardial infarction from acute coronary syndrome PMID: 22838188
    7. Significant increase in plasma glycoprotein BB in patients with hypertrophic cardiomyopathy. PMID: 20482380
    8. Brain-type glycogen phosphorylase is expressed in non-small-cell lung carcinoma, particularly adenocarcinomas, and is an independent poor prognostic factor. PMID: 17393985

    顯示更多

    收起更多

  • 蛋白家族:
    Glycogen phosphorylase family
  • 數據庫鏈接:

    HGNC: 9723

    OMIM: 138550

    KEGG: hsa:5834

    STRING: 9606.ENSP00000216962

    UniGene: Hs.368157



主站蜘蛛池模板: 综合在线 亚洲 成人 欧美| 亚洲 成人 无码 在线观看| 国产日韩在线时看高清视频| 亚洲色成人一区二区三区小说| 亚洲第一无码专区天堂| 少妇人妻挤奶水中文视频毛片| 欧美大片aaaaa免费观看| 色综合久久蜜芽国产精品| 免费午夜无码片在线观看影院 | 亚洲最大激情中文字幕| 2020久热爱精品视频在线观看| 亚洲午夜爱爱香蕉片| 无码尹人久久相蕉无码| 天堂网www天堂资源网| 色诱视频在线观看| 另类内射国产在线| av无码人妻一区二区三区牛牛| h漫全彩纯肉无码网站| 女人被强╳到高潮喷水在线观看| 小雪尝禁果又粗又大的视频| 午夜伦4480yy私人影院| 欧美性受xxxxzooz乱毛| 久久超乳爆乳中文字幕| 又黄又爽又色的视频| 久久国产偷任你爽任你| 中文字幕在线日亚洲9| 全球av集中精品导航福利| 成人亚欧欧美激情在线观看| 亚洲伊人久久精品酒店| 亚洲精品国产suv| 久久人人做人人妻人人玩精品hd| 国产精品99久久免费观看| 无码少妇一区二区性色av| 亚洲国产精品国自产拍av| 国产 校园 另类 小说区| 日韩亚洲欧美精品综合| 极品少妇xxxx| 99精品国产福利在线观看| 久久不见久久见免费视频观看| 一品二品三品中文字幕| 国产精品女上位好爽在线|