在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Glutaredoxin-related protein 5, mitochondrial (GLRX5)

  • 中文名稱:
    人GLRX5重組蛋白
  • 貨號:
    CSB-YP769767HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GLRX5重組蛋白
  • 貨號:
    CSB-EP769767HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GLRX5重組蛋白
  • 貨號:
    CSB-EP769767HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GLRX5重組蛋白
  • 貨號:
    CSB-BP769767HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GLRX5重組蛋白
  • 貨號:
    CSB-MP769767HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GLRX5
  • Uniprot No.:
  • 別名:
    C14orf87; Chromosome 14 open reading frame 87; FLB4739; GLRX 5; Glrx5; GLRX5_HUMAN; Glutaredoxin 5 homolog; Glutaredoxin related protein 5; Glutaredoxin-related protein 5; Glutaredoxin5; GRX5; MGC14129; mitochondrial; Monothiol glutaredoxin-5; PRO1238
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    32-157
  • 氨基酸序列
    AGSGAGGGG SAEQLDALVK KDKVVVFLKG TPEQPQCGFS NAVVQILRLH GVRDYAAYNV LDDPELRQGI KDYSNWPTIP QVYLNGEFVG GCDILLQMHQ NGDLVEELKK LGIHSALLDE KKDQDSK
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.
  • 基因功能參考文獻:
    1. GLRX5 rs1007814 showed a statistically marginally significant difference between cases and controls in genotype frequency (case/control: CC 1:6; CT 112:78; TT 752:505, P=0.049361), but no significant differences in allele distribution [odds ratio (OR)=0.852805]In men, we found a minor difference in the genotype frequency (case/control: CC 0:3; CT 72:36; TT 411:280, P=0.037370) and not in allele distribution (OR=1.142857) PMID: 27893590
    2. Patients with GLRX5-associated variant nonketotic hyperglycemia had normal development with childhood-onset spastic paraplegia, spinal lesion, and optic atrophy. PMID: 24334290
    3. crystal structure of GLRX5 revealed a tetrameric organization with the [2Fe-2S] clusters buried in the interior and shielded from the solvent by the conserved beta1-alpha2 loop PMID: 21029046
    4. Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts PMID: 20364084
    5. No GLRX5 mutations were found among sixty CSA probands examined PMID: 19731322
    6. Mutations in GLRX5 is associated with sideroblastic-like microcytic anemia and iron overload PMID: 17485548

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Anemia, sideroblastic, 3, pyridoxine-refractory (SIDBA3); Spasticity, childhood-onset, with hyperglycinemia (SPAHGC)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    Glutaredoxin family, Monothiol subfamily
  • 數據庫鏈接:

    HGNC: 20134

    OMIM: 609588

    KEGG: hsa:51218

    STRING: 9606.ENSP00000328570

    UniGene: Hs.744943



主站蜘蛛池模板: 日韩亚洲欧美中文在线| 久久超碰精品一夜七次郎| 日韩人妻无码一区二区三区综合部 | 亚洲国产精品无码专区影院| 成人做爰视频www| 国产精品毛片久久久久久久| 无码av波多野结衣久久| 成 人 在 线 免费观看 | 无码国产玉足脚交极品网站| 高潮射精日本韩国在线播放| 成年美女黄网站18禁免费| 蜜臀av无码精品人妻色欲| 国产精品99久久免费黑人人妻 | 激烈的性高湖波多野结衣| 欧美野性肉体狂欢大派对| 无码少妇一区二区三区| 国产精品久久久久久妇女| 一本久道久久综合狠狠老| 国产v片在线播放免费无遮挡| 久久国产乱子伦精品免费台湾| 午夜理论片yy6080私人影院| 国产成人三级一区二区在线观看一 | 中文字幕av无码不卡| 火箭视频在线观看精品| 亚洲乱码日产精品bd在线| 亚洲国产香蕉碰碰人人| 国产av一区二区三区| 韩产日产国产欧产| 好男人日本社区www| 奇米777四色成人影视| 国产初高中生真实在线视频| 欧美人与动牲猛交a欧美精品| 国产av天堂无码一区二区三区| 亚洲另类欧美综合在线| 2021久久超碰国产精品最新| 白嫩少妇激情无码| 天堂а√中文在线官网| 中文字幕无码毛片免费看| 色欲av久久综合人妻无码| 内射女校花一区二区三区| 色综合久久精品亚洲国产|