在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GLRX5 Antibody, Biotin conjugated

  • 中文名稱:
    GLRX5兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA769767LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GLRX5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GLRX5
  • 別名:
    C14orf87 antibody; Chromosome 14 open reading frame 87 antibody; FLB4739 antibody; GLRX 5 antibody; Glrx5 antibody; GLRX5_HUMAN antibody; Glutaredoxin 5 homolog antibody; Glutaredoxin related protein 5 antibody; Glutaredoxin-related protein 5 antibody; Glutaredoxin5 antibody; GRX5 antibody; MGC14129 antibody; mitochondrial antibody; Monothiol glutaredoxin-5 antibody; PRO1238 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Glutaredoxin-related protein 5, mitochondrial protein (32-157AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.
  • 基因功能參考文獻:
    1. GLRX5 rs1007814 showed a statistically marginally significant difference between cases and controls in genotype frequency (case/control: CC 1:6; CT 112:78; TT 752:505, P=0.049361), but no significant differences in allele distribution [odds ratio (OR)=0.852805]In men, we found a minor difference in the genotype frequency (case/control: CC 0:3; CT 72:36; TT 411:280, P=0.037370) and not in allele distribution (OR=1.142857) PMID: 27893590
    2. Patients with GLRX5-associated variant nonketotic hyperglycemia had normal development with childhood-onset spastic paraplegia, spinal lesion, and optic atrophy. PMID: 24334290
    3. crystal structure of GLRX5 revealed a tetrameric organization with the [2Fe-2S] clusters buried in the interior and shielded from the solvent by the conserved beta1-alpha2 loop PMID: 21029046
    4. Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts PMID: 20364084
    5. No GLRX5 mutations were found among sixty CSA probands examined PMID: 19731322
    6. Mutations in GLRX5 is associated with sideroblastic-like microcytic anemia and iron overload PMID: 17485548

    顯示更多

    收起更多

  • 相關疾病:
    Anemia, sideroblastic, 3, pyridoxine-refractory (SIDBA3); Spasticity, childhood-onset, with hyperglycinemia (SPAHGC)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    Glutaredoxin family, Monothiol subfamily
  • 數據庫鏈接:

    HGNC: 20134

    OMIM: 609588

    KEGG: hsa:51218

    STRING: 9606.ENSP00000328570

    UniGene: Hs.744943



主站蜘蛛池模板: 国产欧美日韩精品丝袜高跟鞋| 亚洲成av人片一区二区密柚| 色综合色综合久久综合频道88| 国产亚洲福利在线视频| 国产成人无码精品一区二区三区| 春色校园亚洲愉拍自拍| 伊人久久精品无码二区麻豆| 97久久精品亚洲中文字幕无码| 国产精品久久福利网站| 最近日本mv字幕免费高清完整版 | 国产真实自在自线免费精品| 无码被窝影院午夜看片爽爽jk| 中文字幕无码av免费久久| 男女啪动最猛动态图| 国产精品女同一区二区| 夜夜欢性恔免费视频| 精品国产一区二区三区av色诱| 欧精国精产品一区| 又粗又大内射免费视频小说| 熟女俱乐部五十路六十路av| 最新无码人妻在线不卡| 亚洲国产成人精品无码区在线| 无套内射在线无码播放| 韩国精品一区二区三区无码视频| 久久久久久无码日韩欧美| 国产乱辈通伦影片在线播放亚洲| 久久伊人蜜桃av一区二区| 日本熟妇人妻xxxxx| 国产成人午夜福利在线小电影| 蜜桃少妇av久久久久久久| 五月天激情国产综合婷婷婷| 黄网站欧美内射| 国产传媒麻豆剧精品av国产| 婷婷成人小说综合专区| 人妻 校园 激情 另类| 天堂一区人妻无码| 99九九99九九视频精品| 天堂最新版在线www官网中文地址 最新国产麻豆aⅴ精品无码 | 免费人成在线观看视频无码| 亚洲国产成人爱av网站| 久久99精品久久久久久水蜜桃|