在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human GPI ethanolamine phosphate transferase 1 (PIGN), partial

Recombinant Human GPI ethanolamine phosphate transferase 1 (PIGN), partial

  • 中文名稱：
    人PIGN重組蛋白
  • 貨號：
    CSB-YP017977HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PIGN重組蛋白
  • 貨號：
    CSB-EP017977HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PIGN重組蛋白
  • 貨號：
    CSB-EP017977HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PIGN重組蛋白
  • 貨號：
    CSB-BP017977HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PIGN重組蛋白
  • 貨號：
    CSB-MP017977HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PIGN
  • Uniprot No.：
  • 別名：
    PIGN; MCD4; GPI ethanolamine phosphate transferase 1; EC 2.-.-.-; MCD4 homolog; Phosphatidylinositol-glycan biosynthesis class N protein; PIG-N
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. May act as suppressor of replication stress and chromosome missegregation.
  • 基因功能參考文獻：
    1. Loss of function PIGN alleles causes Fryns syndrome. Founder effect for PIGN intragenic deletion is observed in La Reunion and other Indian Ocean islands. PMID: 29330547
    2. PIGN is a novel biomarker of CIN and leukemic transformation/progression in a subgroup of patients with MDS or AML-MRC. PMID: 28187452
    3. Study reports compound heterozygous mutations in PIGN in two siblings with Fryns syndrome, and a homozygous mutation in an unrelated affected individual. However, two further individuals with Fryns syndrome did not carry mutations in this gene, suggesting genetic heterogeneity in this syndrome. PMID: 27038415
    4. Disease associated mutation L311W reduces enzymatic activity rather than affecting protein levels. PMID: 28327575
    5. PIGN-1/PIGN is required for quality control in Caenorhabditis elegans and in mammalian cells. PMID: 27980068
    6. PIGN mutation is associated with multiple congenital anomalies hypotonia seizures syndrome related epilepsy. PMID: 26394714
    7. The mutated PIGN caused a significant decrease of the overall glycosylphoshatidylinositol-anchored proteins and CD24 expression which is sufficient to cause severe phenotypic expression. PMID: 26364997
    8. Findings confirm that developmental delay, hypotonia, and epilepsy combined with congenital anomalies are common phenotypes of PIGN mutations and add progressive cerebellar atrophy to this clinical spectrum. PMID: 24253414
    9. PIGN encodes phosphatidylinositol-glycan biosynthesis class N protein. PMID: 22876578
    10. Multiple congenital anomalies-hypotonia-seizures syndrome is caused by a mutation in PIGN. PMID: 21493957

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Multiple congenital anomalies-hypotonia-seizures syndrome 1 (MCAHS1)
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    PIGG/PIGN/PIGO family, PIGN subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 8967

    OMIM: 606097

    KEGG: hsa:23556

    STRING: 9606.ENSP00000350263

    UniGene: Hs.157031



主站蜘蛛池模板： 无码av中文字幕久久专区| 国产真实露脸乱子伦原著| 久久久亚洲精品无码| 熟妇人妻无码xxx视频| 春药玩弄少妇高潮吼叫| 成人午夜无码精品免费看| 久久久97丨国产人妻熟女| 国产熟人av一二三区| 污污内射在线观看一区二区少妇| 欧美精品乱码99久久蜜桃| 日本久久综合久久综合| 婷婷色综合视频在线观看| 99精品视频免费热播在线观看| 国产真人性做爰久久网站| 欧美激情一区二区三区在线| 亚洲精品一区国产| 午夜福制92视频| 午夜激成人免费视频在线观看| 亚洲色欲色欲www| 欧美丰满一区二区免费视频| av蓝导航精品导航| 再深点灬舒服灬太大了在线视频 | 人人超碰人人爱超碰国产| 国产精品人人爽人人做我的可爱| 国产人成网线在线播放va| 国产精品禁忌a片特黄a片| 伊人久久大香线蕉无码| 国产精品原创巨作av| 久艹视频免费看| 4hu四虎永久在线影院| 亚洲精品鲁一鲁一区二区三区| 欧美又大又色又爽aaaa片| 亚洲中文字幕无码av| 国产在线无码不卡影视影院| 欧美在线观看免费专区| 欧美牲交a欧美牲交aⅴ久久| 国产69精品久久久久777| 国产日产欧产精品精品app| 在线视频国产制服丝袜| 失禁大喷潮在线播放| 国产区精品系列在线观看|