在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Disheveled-associated activator of morphogenesis 1 (DAAM1), partial

Recombinant Human Disheveled-associated activator of morphogenesis 1 (DAAM1), partial

  • 中文名稱：
    Recombinant Human Disheveled-associated activator of morphogenesis 1(DAAM1) ,partial
  • 貨號：
    CSB-YP896514HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Disheveled-associated activator of morphogenesis 1(DAAM1) ,partial
  • 貨號：
    CSB-EP896514HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Disheveled-associated activator of morphogenesis 1(DAAM1) ,partial
  • 貨號：
    CSB-EP896514HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Disheveled-associated activator of morphogenesis 1(DAAM1) ,partial
  • 貨號：
    CSB-BP896514HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Disheveled-associated activator of morphogenesis 1(DAAM1) ,partial
  • 貨號：
    CSB-MP896514HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    DAAM1; KIAA0666; Disheveled-associated activator of morphogenesis 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Together with DAAM2, required for myocardial maturation and sarcomere assembly.
  • 基因功能參考文獻：
    1. coiling phagocytosis is a mechanism for borrelial internalization by neuroglial cells mediated by Daam1 PMID: 29746581
    2. Results provide evidence that Daam1 activates RhoA to regulate Wnt5ainduced glioblastoma cell invasion. PMID: 29207169
    3. DAAM1 organizes actin filaments into a nodal complex PMID: 27760153
    4. Kank1 plays a crucial role in regulating the activity of RhoA through retrieving excess Daam1 and balancing the activities of RhoA and its effectors. PMID: 28284839
    5. High Daam-1 expression may upregulate the Wnt/PCP pathway and cause idiopathic pulmonary arterial hypertension PMID: 28288669
    6. Kif26b, together with Dvl3/Daam1, initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells. PMID: 26792835
    7. Daam1 plays a dual role in the phagocytic uptake of borreliae. PMID: 24696301
    8. A developmentally restricted function of miR-490 and its putative DAAM1 target are associated with exaggerated megakaryocytopoiesis and/or proplatelet formation. PMID: 22869791
    9. Wnt5a promotes breast cancer cell migration via Dvl2/Daam1/RhoA. PMID: 22655072
    10. DAAM1 is a formin required for centrosome re-orientation during cell migration. PMID: 20927366
    11. Fli-I promotes the GTP-bound active Rho-mediated relief of the autoinhibition of Daam1 and mDia1. Thus, Fli-I is a novel positive regulator of Rho-induced linear actin assembly mediated by DRFs. PMID: 20223827
    12. DAAM1 regulates endothelial cell growth through MT stabilization in a cell type-selective manner PMID: 20351293
    13. DAAM1 was shown to bind to the SH3 domain of CIP4 in vivo. PMID: 16630611
    14. Results report that Profilin1 is an effector downstream of Daam1 required for cytoskeletal changes during gastrulation. PMID: 17021034
    15. The DAAM1 FH2 domain structure, determined at 2.25 A resolution, and DAAM1 actin binding activity PMID: 17482208
    16. Crystal structure of human DAAM1 formin homology 2 domain PMID: 17986009
    17. a carboxyl-terminal binding partner, Dvl, has a role in activation of Daam1 PMID: 18162551
    18. mDia1 and Daam1 are platelet actin assembly factors having distinct efficiencies, and they are directly regulated by Rho GTPases PMID: 18218625

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Perinuclear.
  • 蛋白家族：
    Formin homology family
  • 組織特異性：
    Expressed in all tissues examined.
  • 數據庫鏈接：

    HGNC: 18142

    OMIM: 606626

    KEGG: hsa:23002

    STRING: 9606.ENSP00000247170

    UniGene: Hs.19156



主站蜘蛛池模板： 久久免费视频精品在线| 成人内射国产免费观看| 少妇挑战黑人高潮惨叫| 看国产一毛片在线看手机看| 中文字幕欧美亚州视频免费 | 日韩欧群交p片内射中文| 又硬又粗又大一区二区三区视频| 中文字字幕在线中文乱码| 亚洲中文字幕av每天更新| 美国人性欧美xxxx| 亚洲精品无码一区二区| 骚片av蜜桃精品一区| 国产偷窥盗摄一区二区| 亚洲无线卡一卡二| 无码不卡av东京热毛片| 久久精品国产99久久丝袜蜜桃| 18禁黄污无遮挡无码网站| 国产真实伦在线观看| 久久人人爽人人爽人人片亞洲| 国产欧美成人xxx视频| 人狥杂交一区欧美二区| 国产乱人伦中文无无码视频试看 | 中文字幕v亚洲ⅴv天堂| 亚洲欧美人成网站aaa| 伊人久久大香线蕉综合中文字幕| 精品人伦一区二区三区蜜桃免费 | 丝袜美腿亚洲一区二区| 国产偷亚洲偷欧美偷精品| 欧美一性一乱一交一视频| 欧美激性欧美激情在线| 在线观看国产亚洲视频免费| 欧美大屁股xxxxhd黑色| 久久久av男人的天堂| 中国美女牲交视频| 欧美激情肉欲高潮视频| 亚洲中文字幕丝祙制服| 蜜桃视频在线观看免费网址入口| 性史性农村dvd毛片| 精品亚洲国产成av人片传媒| 亚洲国产日韩一区三区| 欧美三级a做爰在线观看|