在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DAAM1 Antibody

DAAM1 Antibody

  • 中文名稱：
    DAAM1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA135938
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA135938(DAAM1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA135938(DAAM1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, 293T cells, Primary antibody: CSB-PA135938(DAAM1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DAAM1 antibody; KIAA0666 antibody; Disheveled-associated activator of morphogenesis 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human DAAM1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Together with DAAM2, required for myocardial maturation and sarcomere assembly.
  • 基因功能參考文獻(xiàn)：
    1. coiling phagocytosis is a mechanism for borrelial internalization by neuroglial cells mediated by Daam1 PMID: 29746581
    2. Results provide evidence that Daam1 activates RhoA to regulate Wnt5ainduced glioblastoma cell invasion. PMID: 29207169
    3. DAAM1 organizes actin filaments into a nodal complex PMID: 27760153
    4. Kank1 plays a crucial role in regulating the activity of RhoA through retrieving excess Daam1 and balancing the activities of RhoA and its effectors. PMID: 28284839
    5. High Daam-1 expression may upregulate the Wnt/PCP pathway and cause idiopathic pulmonary arterial hypertension PMID: 28288669
    6. Kif26b, together with Dvl3/Daam1, initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells. PMID: 26792835
    7. Daam1 plays a dual role in the phagocytic uptake of borreliae. PMID: 24696301
    8. A developmentally restricted function of miR-490 and its putative DAAM1 target are associated with exaggerated megakaryocytopoiesis and/or proplatelet formation. PMID: 22869791
    9. Wnt5a promotes breast cancer cell migration via Dvl2/Daam1/RhoA. PMID: 22655072
    10. DAAM1 is a formin required for centrosome re-orientation during cell migration. PMID: 20927366
    11. Fli-I promotes the GTP-bound active Rho-mediated relief of the autoinhibition of Daam1 and mDia1. Thus, Fli-I is a novel positive regulator of Rho-induced linear actin assembly mediated by DRFs. PMID: 20223827
    12. DAAM1 regulates endothelial cell growth through MT stabilization in a cell type-selective manner PMID: 20351293
    13. DAAM1 was shown to bind to the SH3 domain of CIP4 in vivo. PMID: 16630611
    14. Results report that Profilin1 is an effector downstream of Daam1 required for cytoskeletal changes during gastrulation. PMID: 17021034
    15. The DAAM1 FH2 domain structure, determined at 2.25 A resolution, and DAAM1 actin binding activity PMID: 17482208
    16. Crystal structure of human DAAM1 formin homology 2 domain PMID: 17986009
    17. a carboxyl-terminal binding partner, Dvl, has a role in activation of Daam1 PMID: 18162551
    18. mDia1 and Daam1 are platelet actin assembly factors having distinct efficiencies, and they are directly regulated by Rho GTPases PMID: 18218625

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Perinuclear.
  • 蛋白家族：
    Formin homology family
  • 組織特異性：
    Expressed in all tissues examined.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18142

    OMIM: 606626

    KEGG: hsa:23002

    STRING: 9606.ENSP00000247170

    UniGene: Hs.19156



主站蜘蛛池模板： 亚洲情a成黄在线观看| 青青草国产线观看| 少妇爆乳无码专区网站| 国产性色播播毛片| 老熟妇仑乱一区二区视頻| 国产午夜鲁丝无码拍拍| 亚洲国产中文曰韩丝袜| 日本黄网站免费| 国产精品v欧美精品∨日韩| 国产白浆喷水在线视频| 自偷自拍亚洲综合精品麻豆| 欧美顶级少妇做爰hd| 热re99久久精品国产66热| 人人爽人人爽人人片av东京热| 亚洲精品自产拍在线观看亚瑟| 精品成在人线av无码免费看| 国产免费无码一区二区视频| 97超碰国产精品无码分类| 免费国产黄线在线观看| 欧美国产精品日韩在线| 日韩理论午夜无码| 尤物蜜芽国产成人精品区| 精产一二三产区m553| 国产麻豆剧果冻传媒一区| 亚洲午夜无码久久久久小说| 亚洲精品国产av成拍色拍婷婷| 国产成人艳妇aa视频在线| 加比勒色综合久久| 高中国产开嫩苞实拍视频在线观看| 国产98在线 | 免费、| 欧美丰满妇大ass| 大伊香蕉在线精品视频75| 天堂无码人妻精品一区二区三区| 豆国产97在线 | 亚洲| 亚洲亚洲熟妇色l图片20p| 成人国产一区二区精品小说| 久久国产欧美日韩精品| 无码av中文字幕免费放| 宅男色影视亚洲人在线| 日本熟妇浓毛| 黑色丝袜脚足国产在线看|