在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DAAM1 Antibody

DAAM1 Antibody

  • 中文名稱：
    DAAM1兔多克隆抗體
  • 貨號：
    CSB-PA006477GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DAAM1 antibody; KIAA0666 antibody; Disheveled-associated activator of morphogenesis 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human DAAM1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Together with DAAM2, required for myocardial maturation and sarcomere assembly.
  • 基因功能參考文獻：
    1. coiling phagocytosis is a mechanism for borrelial internalization by neuroglial cells mediated by Daam1 PMID: 29746581
    2. Results provide evidence that Daam1 activates RhoA to regulate Wnt5ainduced glioblastoma cell invasion. PMID: 29207169
    3. DAAM1 organizes actin filaments into a nodal complex PMID: 27760153
    4. Kank1 plays a crucial role in regulating the activity of RhoA through retrieving excess Daam1 and balancing the activities of RhoA and its effectors. PMID: 28284839
    5. High Daam-1 expression may upregulate the Wnt/PCP pathway and cause idiopathic pulmonary arterial hypertension PMID: 28288669
    6. Kif26b, together with Dvl3/Daam1, initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells. PMID: 26792835
    7. Daam1 plays a dual role in the phagocytic uptake of borreliae. PMID: 24696301
    8. A developmentally restricted function of miR-490 and its putative DAAM1 target are associated with exaggerated megakaryocytopoiesis and/or proplatelet formation. PMID: 22869791
    9. Wnt5a promotes breast cancer cell migration via Dvl2/Daam1/RhoA. PMID: 22655072
    10. DAAM1 is a formin required for centrosome re-orientation during cell migration. PMID: 20927366
    11. Fli-I promotes the GTP-bound active Rho-mediated relief of the autoinhibition of Daam1 and mDia1. Thus, Fli-I is a novel positive regulator of Rho-induced linear actin assembly mediated by DRFs. PMID: 20223827
    12. DAAM1 regulates endothelial cell growth through MT stabilization in a cell type-selective manner PMID: 20351293
    13. DAAM1 was shown to bind to the SH3 domain of CIP4 in vivo. PMID: 16630611
    14. Results report that Profilin1 is an effector downstream of Daam1 required for cytoskeletal changes during gastrulation. PMID: 17021034
    15. The DAAM1 FH2 domain structure, determined at 2.25 A resolution, and DAAM1 actin binding activity PMID: 17482208
    16. Crystal structure of human DAAM1 formin homology 2 domain PMID: 17986009
    17. a carboxyl-terminal binding partner, Dvl, has a role in activation of Daam1 PMID: 18162551
    18. mDia1 and Daam1 are platelet actin assembly factors having distinct efficiencies, and they are directly regulated by Rho GTPases PMID: 18218625

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Perinuclear.
  • 蛋白家族：
    Formin homology family
  • 組織特異性：
    Expressed in all tissues examined.
  • 數據庫鏈接：

    HGNC: 18142

    OMIM: 606626

    KEGG: hsa:23002

    STRING: 9606.ENSP00000247170

    UniGene: Hs.19156



主站蜘蛛池模板： 熟女人妻av粗壮巨龙| 精品国产乱码久久久久久婷婷| 色鬼7777久久| 国产99久久久国产精品免费看| 亚洲精品久久7777777国产| 国产产品亚洲产品| 久久精品蜜芽亚洲国产av| 成 人 在 线 免费观看| 久久精品成人欧美大片| 在线精品无码字幕无码av| 亚洲最新无码中文字幕久久| 国产麻豆乱子伦午夜视频观看| 国产精品aⅴ在线观看| 人体内射精一区二区三区| 酒店大战丝袜高跟鞋人妻| 日韩精品无码专区免费视频| 两个男人吮她的花蒂和奶水视频 | 777天堂麻豆爱综合视频| 国产麻豆精品一区二区三区v视界| 天堂资源中文最新版在线一区| 国产精品三级av三级av三级| 无码免费一区二区三区| 亚洲日韩av无码一区二区三区| 在线亚洲综合欧美网站首页| 亚瑟av亚洲精品一区二区| 97精品人人a片免费看| 一本久道久久综合狠狠躁av| 67194熟妇人妻欧美日韩| 人妻互换一二三区激情视频 | 2017亚洲天堂最新地址| 性欧美俄罗斯乱妇| 高潮喷水的毛片| 亚洲中文无码a∨在线观看| 亚洲乱亚洲乱妇无码麻豆| 国内精品久久久久影院一蜜桃| 久久777国产线看观看精品| 国内精品乱码卡一卡2卡麻豆| 日本一区午夜艳熟免费| 中文字幕在线观看亚洲视频| 无码h黄肉动漫在线观看| 亚洲精品中国国产嫩草影院美女|