在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human DNA replication complex GINS protein PSF1 (GINS1)

  • 中文名稱:
    人GINS1重組蛋白
  • 貨號:
    CSB-YP617926HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GINS1重組蛋白
  • 貨號:
    CSB-EP617926HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GINS1重組蛋白
  • 貨號:
    CSB-EP617926HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GINS1重組蛋白
  • 貨號:
    CSB-BP617926HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GINS1重組蛋白
  • 貨號:
    CSB-MP617926HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GINS1
  • Uniprot No.:
  • 別名:
    DNA replication complex GINS protein PSF1; GINS complex subunit 1 (Psf1 homolog); GINS complex subunit 1; GINS1; partner of sld five-1; partner of sld5; PSF1 homolog; PSF1_HUMAN; RP4-691N24.2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-196
  • 氨基酸序列
    MFCEKAMELI RELHRAPEGQ LPAFNEDGLR QVLEEMKALY EQNQSDVNEA KSGGRSDLIP TIKFRHCSLL RNRRCTVAYL YDRLLRIRAL RWEYGSVLPN ALRFHMAAEE MEWFNNYKRS LATYMRSLGG DEGLDITQDM KPPKSLYIEV RCLKDYGEFE VDDGTSVLLK KNSQHFLPRW KCEQLIRQGV LEHILS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
  • 基因功能參考文獻:
    1. The authors show that GINS is a compact tetramer in solution as observed in crystal structures, but also forms a double-tetrameric population, detectable by electron microscopy. PMID: 28071757
    2. Autosomal recessive, partial GINS1 deficiency impairs DNA replication and underlies intra-uterine (and postnatal) growth retardation, chronic neutropenia, and NK cell deficiency. PMID: 28414293
    3. PSF1 mRNA expression was an independent factor associated with prognosis of colorectal cancer. PMID: 21713706
    4. These results suggest that PSF1 over-expression is specifically involved in breast cancer cell growth. PMID: 20825491
    5. Findings implicate PSF1 in tumorigenesis and offer initial evidence of its potential as a theranostic target. PMID: 20103637
    6. expression of mammalian GINS is regulated by 17beta-Estradiol-stimulated estrogen receptor alpha, and PSF3 acts as a gene responsive to transcription factor E2F1 PMID: 17127213
    7. the C-terminal domain of Psf1 does not contribute to the stability of the GINS complex but is crucial for chromatin binding and replication activity PMID: 17417653

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Chromosome.
  • 蛋白家族:
    GINS1/PSF1 family
  • 數據庫鏈接:

    HGNC: 28980

    OMIM: 610608

    KEGG: hsa:9837

    STRING: 9606.ENSP00000262460

    UniGene: Hs.658464



主站蜘蛛池模板: 一本精品中文字幕在线| 日日摸日日碰夜夜爽亚洲| 亚洲精品中文字幕乱码| 国产精品美女久久久久久2018| 中文字幕av久久激情亚洲精品| 亚洲中文字幕第一页在线| 欧美变态口味重另类在线视频| 日韩av无码精品人妻系列| 又爽又黄无遮拦成人网站| 137日本免费肉体摄影| 日韩吃奶摸下aa片免费观看| 欧美偷窥清纯综合图区| 成人欧美一区在线视频| 久久青草成人综合网站| 国产无吗一区二区三区在线欢| 日韩av无码中文字幕| 色婷婷五月综合激情中文字幕| 少妇久久久久久人妻无码| 国产凹凸在线一区二区| 无码高潮少妇毛多水多水免费| 欧美人与动人物姣配xxxx| 人妻插b视频一区二区三区| 无码人妻精品一区二区三区9厂| 无码人妻丰满熟妇区毛片18| 韩国 欧美 日产 国产精品| 亚洲欧美乱综合图片区小说区 | 中文字幕av无码专区第一页| 亚洲第一成人网站| 国产女人爽的流水毛片| 精品一区二区三区影院在线午夜| 天堂8在线天堂资源bt| 日本55丰满熟妇厨房伦| 一二三四视频社区3在线高清| 亚洲精品伊人久久久大香| 国产在线国偷精品免费看| 老司机无码精品a| 韩国三级l中文字幕无码| 国精产品999国精产品官网| 精品久久久久久无码国产| 国产免费福利在线视频| 亚洲人成网网址在线看|