在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GINS1 Antibody, Biotin conjugated

  • 中文名稱:
    GINS1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA617926LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GINS1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GINS1
  • 別名:
    DNA replication complex GINS protein PSF1 antibody; GINS complex subunit 1 (Psf1 homolog) antibody; GINS complex subunit 1 antibody; GINS1 antibody; partner of sld five-1 antibody; partner of sld5 antibody; PSF1 homolog antibody; PSF1_HUMAN antibody; RP4-691N24.2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human DNA replication complex GINS protein PSF1 protein (1-196AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
  • 基因功能參考文獻:
    1. The authors show that GINS is a compact tetramer in solution as observed in crystal structures, but also forms a double-tetrameric population, detectable by electron microscopy. PMID: 28071757
    2. Autosomal recessive, partial GINS1 deficiency impairs DNA replication and underlies intra-uterine (and postnatal) growth retardation, chronic neutropenia, and NK cell deficiency. PMID: 28414293
    3. PSF1 mRNA expression was an independent factor associated with prognosis of colorectal cancer. PMID: 21713706
    4. These results suggest that PSF1 over-expression is specifically involved in breast cancer cell growth. PMID: 20825491
    5. Findings implicate PSF1 in tumorigenesis and offer initial evidence of its potential as a theranostic target. PMID: 20103637
    6. expression of mammalian GINS is regulated by 17beta-Estradiol-stimulated estrogen receptor alpha, and PSF3 acts as a gene responsive to transcription factor E2F1 PMID: 17127213
    7. the C-terminal domain of Psf1 does not contribute to the stability of the GINS complex but is crucial for chromatin binding and replication activity PMID: 17417653

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Chromosome.
  • 蛋白家族:
    GINS1/PSF1 family
  • 數據庫鏈接:

    HGNC: 28980

    OMIM: 610608

    KEGG: hsa:9837

    STRING: 9606.ENSP00000262460

    UniGene: Hs.658464



主站蜘蛛池模板: 色综合久久无码中文字幕| 成人性无码专区免费视频| 欧美性白人极品1819hd| 人妻无码久久精品| 无遮挡裸体免费视频尤物| 国产区在线观看成人精品| 亚洲va在线va天堂xxxx中文| 99精品人妻无码专区在线视频区| 久久aⅴ人妻少妇嫩草影院| 亚洲日韩av无码| 人妻体体内射精一区二区| 青草影院内射中出高潮-百度| 国产三级农村妇女在线| 免免费国产aaaaa片| 97人人模人人爽人人少妇| 国色天香天天影院综合网 | 曰本女人与公拘交酡| 性色av无码中文av有码vr| 欧美人与动性xxxxbbbb| 东京热加勒比无码少妇| 插我舔内射18免费视频| 久久九九有精品国产23百花影院| 亚洲一卡2卡3卡4卡5卡乱码观看 | 国产精品爽爽v在线观看无码| 久久99精品国产麻豆蜜芽| 国产农村黄aaaaa特黄av毛片 | 亚洲色成人www永久在线观看| 无罩大乳的熟妇正在播放| 日本狂喷奶水在线播放212| 亚洲欧美中文高清在线专区| 免费观看黄网站在线播放| 欧美不卡高清一区二区三区| av免费播放一区二区三区| 人人爽人人爽人人爽| 国产在视频线精品视频| 国产成人无码av片在线观看不卡| 无遮挡免费高清羞羞视频| 成人免费无码av| 国产精品白浆在线观看免费| 97人人超碰国产精品最新| 国产小呦泬泬99精品|