在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GINS1 Antibody

  • 中文名稱:
    GINS1兔多克隆抗體
  • 貨號:
    CSB-PA945809
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA945809(GINS1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA945809(GINS1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    GINS1
  • 別名:
    DNA replication complex GINS protein PSF1 antibody; GINS complex subunit 1 (Psf1 homolog) antibody; GINS complex subunit 1 antibody; GINS1 antibody; partner of sld five-1 antibody; partner of sld5 antibody; PSF1 homolog antibody; PSF1_HUMAN antibody; RP4-691N24.2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human GINS1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
  • 基因功能參考文獻:
    1. The authors show that GINS is a compact tetramer in solution as observed in crystal structures, but also forms a double-tetrameric population, detectable by electron microscopy. PMID: 28071757
    2. Autosomal recessive, partial GINS1 deficiency impairs DNA replication and underlies intra-uterine (and postnatal) growth retardation, chronic neutropenia, and NK cell deficiency. PMID: 28414293
    3. PSF1 mRNA expression was an independent factor associated with prognosis of colorectal cancer. PMID: 21713706
    4. These results suggest that PSF1 over-expression is specifically involved in breast cancer cell growth. PMID: 20825491
    5. Findings implicate PSF1 in tumorigenesis and offer initial evidence of its potential as a theranostic target. PMID: 20103637
    6. expression of mammalian GINS is regulated by 17beta-Estradiol-stimulated estrogen receptor alpha, and PSF3 acts as a gene responsive to transcription factor E2F1 PMID: 17127213
    7. the C-terminal domain of Psf1 does not contribute to the stability of the GINS complex but is crucial for chromatin binding and replication activity PMID: 17417653

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Chromosome.
  • 蛋白家族:
    GINS1/PSF1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 28980

    OMIM: 610608

    KEGG: hsa:9837

    STRING: 9606.ENSP00000262460

    UniGene: Hs.658464



主站蜘蛛池模板: 午夜影视免费x看| 国内精品乱码卡一卡2卡麻豆| 少妇人妻久久无码专区| 性生交片免费无码看人| 四虎精品成人免费视频| 国产a三级久久精品| 亚洲乱码卡一卡二卡新区仙踪木木 | 国产色播av在线观看| 免费国产精品视频在线| 国产精品美女久久久久av爽 | 精品夜夜爽欧美毛片视频| 亚洲欧美日韩综合在线一| 中文字幕亚洲男人的天堂网络| 午夜成人亚洲理论片在线观看| 毛片内射-百度| 国模冰莲极品自慰人体| 黑色丝袜脚足国产在线看| 好吊射视频988gaocom| gv天堂gv无码男同在线观看 | 久久国产精品2020免费| 就去干成人网| 婷婷久久综合九色综合88| 女人被狂爆到高潮免费视频| 2021在线不卡国产麻豆| 国内精品视频一区二区三区| 久久久久国产一区二区三区| 又爽又色禁片1000视频免费看| 丰满少妇高潮惨叫久久久| 性做久久久久久久久| 欧美性生交xxxxx久久久| 亚洲精品无码成人片| 我的性奴的肉玩具1一17心奴| 亚洲成在人线视av| 四虎亚洲精品成人a在线观看| 久久草莓香蕉频线观| yy111111少妇无码影院| 成年女人免费v片| 偷自拍亚洲视频在线观看99| 日本公妇乱偷中文字幕| 国产精品无码av天天爽播放器 | 日产精品卡2卡三卡乱码网站 |