在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Cystatin-SN (CST1)

Recombinant Human Cystatin-SN (CST1)

  • 中文名稱：
    Recombinant Human Cystatin-SN(CST1)
  • 貨號：
    CSB-YP006088HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Cystatin-SN(CST1)
  • 貨號：
    CSB-EP006088HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Cystatin-SN(CST1)
  • 貨號：
    CSB-EP006088HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Cystatin-SN(CST1)
  • 貨號：
    CSB-BP006088HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Cystatin-SN(CST1)
  • 貨號：
    CSB-MP006088HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CST1
  • Uniprot No.：
  • 別名：
    CST1; Cystain SAI; Cystain-SA-I; Cystatin 1; Cystatin-1; Cystatin-SN; Cystatin1; Cysteine proteinase inhibitor, type 2 family; CYTN; CYTN_HUMAN; Salivary cystatin SA1; Salivary cystatin-SA-1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    21-141
  • 氨基酸序列
    WSPKEEDRII PGGIYNADLN DEWVQRALHF AISEYNKATK DDYYRRPLRV LRARQQTVGG VNYFFDVEVG RTICTKSQPN LDTCAFHEQP ELQKKQLCSF EIYEVPWENR RSLVKSRCQE S
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.
  • 基因功能參考文獻：
    1. Results revealed that CST1 expression was upregulated in colon cancer (CC) compared with normal tissues and contributed to CC cell proliferation. PMID: 29845224
    2. High CST1 expression is negatively correlated with survival of breast cancer patients. CST1 promotes cell proliferation, clone formation, and metastasis in breast cancer cells. CST1 is a novel potential prognostic biomarker and therapeutic target for breast cancer. PMID: 28523467
    3. this results identified cystatin 1 as a biomarker in patients with seasonal allergic rhinitis PMID: 28633877
    4. These results indicate that CST1-mediated extracellular CatB activity enhances tumor development by preventing cellular senescence. PMID: 28383558
    5. interactions of human family 1 & 2 cystatins with cathepsin L1 PMID: 27764212
    6. high expression of Cystatin SN is a significant prognostic indicator of a higher rate of recurrence, metastatic risk, and poor survival in patients with surgically resected NSCLCs. PMID: 25648368
    7. In conclusion, our data suggest that CST1 might contribute to the proliferation of pancreatic cancer cells and could be a potential biomarker for the early detection of pancreatic cancer. PMID: 25577248
    8. CST1 may contribute to inactivation of protease allergens and help re-establish homeostasis of the nasal membranes. PMID: 23950865
    9. CST1 expression at both the messenger RNA and protein levels was barely detected in control cells, which included early passage proliferating, quiescent, or immortal human fibroblasts PMID: 21636832
    10. Murine monoclonal antibodies were made which can distinguish between CST1 and CST2. PMID: 15829315
    11. CST1 might be highly involved in gastric tumorigenesis and regulate the proteolytic activity of cysteine proteases. PMID: 19463800
    12. Identification of Cystatin SN as a novel tumor marker for colorectal cancer. PMID: 19513549

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Cystatin family
  • 組織特異性：
    Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid.
  • 數據庫鏈接：

    HGNC: 2473

    OMIM: 123855

    KEGG: hsa:1469

    STRING: 9606.ENSP00000305731

    UniGene: Hs.123114



主站蜘蛛池模板： 久久99精品久久久久久水蜜桃| 黑人大战日本人妻嗷嗷叫不卡视频| 亚洲成亚洲成网| 日本一卡二卡四卡无卡国产| 国产女人18毛片水真多| 亚洲日本va中文字幕| 在线观看免费网页欧美成| 四库影院永久国产精品地址 | 久久亚洲精品人成综合网| 护士人妻hd中文字幕| 高级会所人妻互换94部分| 97在线精品视频免费| 无码中文字幕va精品影院| 亚洲线精品一区二区三区影音先锋| 亚洲午夜未满十八勿入网站| 日韩 无码 偷拍 中文字幕| 久久天天躁夜夜躁狠狠综合| 欧洲精品卡一卡二卡三| 亚洲人成网站18禁止无码| 国产午夜亚洲精品不卡| 人妻少妇精品视中文字幕国语| 久久久久久av无码免费网站| 日本丰满熟妇videossex8k| 国语精品福利自产拍在线观看 | 天天爽夜夜爽人人爽88| 老熟女重囗味hdxx70星空| 亚洲精品456在线播放| 久久久亚洲精品无码| 亚洲精品在看在线观看| 亚洲成av人片一区二区梦乃| 亚洲精品无码久久久久久久| 2019久久视频这里有精品15| 伊人久久大香线蕉无码不卡| 欧美影院成年免费版| 在线 | 一区二区三区| 波多野结衣乱码中文字幕| 国产成人精品999视频| 高潮喷水的毛片| 日韩精品中文字幕无码专区| 美女扒开腿让男人桶爽揉| 日本免费一区二区三区视频观看|