在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Carboxypeptidase D (CPD), partial

  • 中文名稱:
    Recombinant Human Carboxypeptidase D(CPD) ,partial
  • 貨號:
    CSB-YP005885HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Carboxypeptidase D(CPD) ,partial
  • 貨號:
    CSB-EP005885HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Carboxypeptidase D(CPD) ,partial
  • 貨號:
    CSB-EP005885HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Carboxypeptidase D(CPD) ,partial
  • 貨號:
    CSB-BP005885HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Carboxypeptidase D(CPD) ,partial
  • 貨號:
    CSB-MP005885HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CPD
  • Uniprot No.:
  • 別名:
    Carboxypeptidase D; CBPD_HUMAN; Cpd; gp180 ; Metallocarboxypeptidase D
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. prolactin induction of VEGF-C and Runx2 was inhibited partly by Carboxypeptidase-D inhibitors, implicating nitric oxide , produced by PRL-regulated Carboxypeptidase-D, in breast cancer progression PMID: 28364216
    2. Carboxypeptidase-D (CPD) overexpression coincides with high-grade lung cancer and the CPD overexpression could reverse the inhibitory effects of miR-214 PMID: 27494742
    3. The human carboxypeptidase D transthyretin-like domain forms amyloid under physiological conditions. PMID: 25294878
    4. Prolactin and R1881, acting through Stat5 and androgen receptor, act cooperatively to stimulate CPD gene transcription in breast cancer cells. PMID: 24433040
    5. CPD immunostaining and testosterone/prolactin-stimulated CPD expression were higher in prostate cancer than benign tissues/cells. Elevated CPD increased NO production, which was abolished when both androgen and prolactin receptors were inhibited. PMID: 24615730
    6. Carboxypeptidase D (CPD) is frequently upregulated in hepatocellular carcinoma; targeting CPD inhibits hepatocellular carcinoma cell proliferation through induction of G1 cell-cycle arrest and apoptosis. PMID: 23589395
    7. Either high glucose or insulin (with low glucose) up-regulates beta-cell CPD (but not CPE). PMID: 21628999
    8. Palmitoylation of carboxypeptidase D has a role in intracellular trafficking PMID: 12643288
    9. The isolation and characterization of CPD from several haematopoietic tumour cells are reported. PMID: 15918796
    10. First report to demonstrate carboxypeptidase D as part of the transforming growth factor (TGF)-beta pathway as a TGF-beta target gene implicated in the pathogenesis of lupus erythematosus. PMID: 17641957
    11. prolactin or E2 up-regulated CPD mRNA and protein expression in MCF-7 breast cancer cells promoting their survival PMID: 18535109
    12. CPD releases C-terminal Arg from peptides to provide the precursor substrate for inducible nitric oxide synthase, which enhances nitric oxide synthesis in macrophages. PMID: 11306718

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Peptidase M14 family
  • 組織特異性:
    Highly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines.
  • 數據庫鏈接:

    HGNC: 2301

    OMIM: 603102

    KEGG: hsa:1362

    STRING: 9606.ENSP00000225719

    UniGene: Hs.446079



主站蜘蛛池模板: 免费啪视频在线观看视频日本| 在厨房拨开内裤进入在线视频| 国产精品被窝福利一区| 亚洲欧美日韩中文二区| 国产亚洲精品一区二三区| 国产成人高清精品亚洲| 国产亚洲婷婷香蕉久久精品| 欧美午夜精品一区二区三区电影| 久久影视久久午夜| 亚洲精品无码成人片久久| 亚洲人成人无码www影院 | 欧美肥老太牲交| 中国少妇偷人hd| 中文字幕精品一区二区2021年| 男女猛烈无遮挡免费视频| 98色婷婷在线| 亚洲色大成网站www永久在线观看| 亚洲精品一区二三区不卡| 酒店大战丝袜高跟鞋人妻| 曰韩欧美群交p片内射| 在教室伦流澡到高潮h麻豆| 国产高清不卡一区二区 | 色哟哟网站在线观看| 粗壮挺进人妻水蜜桃成熟漫画 | 国产老熟女网站| 无修无码h里番在线播放网站| 99r在线精品视频在线播放| 免免费国产aaaaa片| 久久人人爽人人爽人人片亞洲| 成年无码av片| 揉捏奶头高潮呻吟视频| 又大又粗又爽免费视频a片| 99精品国产一区二区三区a片| 久久精品国产导航| av无码小缝喷白浆在线观看| 丰满少妇大叫太大太粗| 少妇极品熟妇人妻200片| 久久久久国色av免费看| 久久精品免视看国产成人明星 | 欧洲乱码伦视频免费| 国产一区二区三区免费高清在线播放 |