在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CPD Antibody

CPD Antibody

  • 中文名稱：
    CPD兔多克隆抗體
  • 貨號(hào)：
    CSB-PA2107ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA2107ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA2107ESR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CPD Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CPD
  • 別名：
    Carboxypeptidase D antibody; CBPD_HUMAN antibody; Cpd antibody; gp180 antibody; Metallocarboxypeptidase D antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Carboxypeptidase D protein (860-1100AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. prolactin induction of VEGF-C and Runx2 was inhibited partly by Carboxypeptidase-D inhibitors, implicating nitric oxide , produced by PRL-regulated Carboxypeptidase-D, in breast cancer progression PMID: 28364216
    2. Carboxypeptidase-D (CPD) overexpression coincides with high-grade lung cancer and the CPD overexpression could reverse the inhibitory effects of miR-214 PMID: 27494742
    3. The human carboxypeptidase D transthyretin-like domain forms amyloid under physiological conditions. PMID: 25294878
    4. Prolactin and R1881, acting through Stat5 and androgen receptor, act cooperatively to stimulate CPD gene transcription in breast cancer cells. PMID: 24433040
    5. CPD immunostaining and testosterone/prolactin-stimulated CPD expression were higher in prostate cancer than benign tissues/cells. Elevated CPD increased NO production, which was abolished when both androgen and prolactin receptors were inhibited. PMID: 24615730
    6. Carboxypeptidase D (CPD) is frequently upregulated in hepatocellular carcinoma; targeting CPD inhibits hepatocellular carcinoma cell proliferation through induction of G1 cell-cycle arrest and apoptosis. PMID: 23589395
    7. Either high glucose or insulin (with low glucose) up-regulates beta-cell CPD (but not CPE). PMID: 21628999
    8. Palmitoylation of carboxypeptidase D has a role in intracellular trafficking PMID: 12643288
    9. The isolation and characterization of CPD from several haematopoietic tumour cells are reported. PMID: 15918796
    10. First report to demonstrate carboxypeptidase D as part of the transforming growth factor (TGF)-beta pathway as a TGF-beta target gene implicated in the pathogenesis of lupus erythematosus. PMID: 17641957
    11. prolactin or E2 up-regulated CPD mRNA and protein expression in MCF-7 breast cancer cells promoting their survival PMID: 18535109
    12. CPD releases C-terminal Arg from peptides to provide the precursor substrate for inducible nitric oxide synthase, which enhances nitric oxide synthesis in macrophages. PMID: 11306718

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Peptidase M14 family
  • 組織特異性：
    Highly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2301

    OMIM: 603102

    KEGG: hsa:1362

    STRING: 9606.ENSP00000225719

    UniGene: Hs.446079



主站蜘蛛池模板： 日韩欧美精品有码在线| 无码av中文字幕免费放| 国产精品无码a∨果冻传媒| 欧美 日韩 国产 另类 图片区| 天天爽夜夜爽人人爽曰| 成人免费的视频| 中文字幕卡二和卡三的视频| 日本免费人成在线观看网站| 漂亮人妻被中出中文字幕| 中文字幕在线观看亚洲视频| 亚洲综合狠狠丁香五月| 波多野结衣超清无码专区| 中文字幕 人妻熟女| 爆爽久久久一区二区又大又黄又嫩 | 亚洲人成人网站色www| 亚洲性无码一区二区三区| 国产老太睡小伙子视频| 大伊香蕉精品一区视频在线| 亚洲永久网址在线观看| 全球成人中文在线| 好硬好湿好爽再深一点动态图视频| 久久99国产亚洲高清观看首页| 国产未发育呦交视频| 日本护士xxxxhd少妇| 又大又粗又爽免费视频a片 | 99视频国产精品免费观看| 国产国拍精品av在线观看按摩| 特黄大片又粗又大又暴| 国产免费人成视频尤勿视频| 成人爽a毛片在线视频淮北| 日韩精品一区二区三区| 久久久无码人妻精品无码| 成人无码视频97免费| 免费人成小说在线观看网站| 欧美xxxx做受欧美| 狠狠色噜噜狠狠狠狠色综合久av| 亚洲欧洲日产国码无码| 日本中文字幕有码在线视频| 欧美老妇bbbwwbbbww| 人妻无码熟妇乱又伦精品视频| 欧洲乱码伦视频免费|