在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human CMRF35-like molecule 1 (CD300LF), partial

Recombinant Human CMRF35-like molecule 1 (CD300LF), partial

  • 中文名稱：
    Recombinant Human CMRF35-like molecule 1(CD300LF),partial
  • 貨號：
    CSB-BP819470HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human CMRF35-like molecule 1(CD300LF),partial
  • 貨號：
    CSB-EP819470HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human CMRF35-like molecule 1(CD300LF),partial
  • 貨號：
    CSB-MP819470HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    CD300LF
  • Uniprot No.：
  • 別名：
    CD300 antigen like family member; CD300 antigen-like family member F; CD300 molecule like family member f; CD300f; CD300LF; CLM; CLM-1; CLM1; CLM1_HUMAN; CMRF35-like molecule 1; IGSF; IgSF13; Immune receptor expressed on myeloid cells 1; immune receptor expressed on myeloid cells; immunoglobin superfamily member; Immunoglobulin superfamily member 13; Immunoglobulin superfamily member; Inhibitory receptor IREM1; IREM; IREM-1; IREM1; Nepmucin; NK inhibitory receptor; NKIR; TREM; triggering receptors expressed on myeloid cells; UNQ3105/PRO10111
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 表達區域：
    20-156aa
  • 氨基酸序列
    TQITGPTTVNGLERGSLTVQCVYRSGWETYLKWWCRGAIWRDCKILVKTSGSEQEVKRDRVSIKDNQKNRTFTVTMEDLMKTDADTYWCGIEKTGNDLGVTVQVTIDPAPVTQEETSSSPTLTGHHLDNRHKLLKLS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.
  • 基因功能參考文獻：
    1. this study demonstrates the role of CD300f in governing innate immune eosinophil activities in pediatric Crohn's disease patients and in active ulcerative colitis patients PMID: 27118491
    2. findings suggest that two rare heterozygous truncating variations (RPS24 Q191X and CD300LF P261fsX266) are risk candidates for autism spectrum disorder. PMID: 25601189
    3. The data suggest that the neuroprotective role of CD300f would be the result of a complex network of cell interactions. PMID: 21951326
    4. peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling PMID: 22288587
    5. CD300f blocked the activation of cells induced by all TLR ligands PMID: 22043923
    6. Data indicate that CD300F is an active regulator of TLR-mediated macrophage activation through association with SHP-1 involving MyD88 and/or TRIF. PMID: 21536801
    7. Findings indicate that IREM-1 exerted its inhibitory effect on BAFF-medicated signalling through ITIM-mediated regulation of ERK activities in THP-1 cells. PMID: 20646006
    8. IgSF13 was identified from dendritic cells; preferentially expressed in myelo-monocytic cells, including monocytes, monocyte-derived DC and monocyte-related cell lines; may be involved in the negative regulation of specific leukocyte population [IgSF13] PMID: 15184070
    9. a novel inhibitory receptor of the Ig superfamily in myeloid cells. (IREM-1 = immune receptor expressed on myeloid cells-1) PMID: 15549731
    10. reveal a putative functional duality of the IREM-1 myeloid cell receptor PMID: 17202342

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    CD300 family
  • 組織特異性：
    Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocy
  • 數據庫鏈接：

    HGNC: 29883

    OMIM: 609807

    KEGG: hsa:146722

    STRING: 9606.ENSP00000327075

    UniGene: Hs.567706



主站蜘蛛池模板： 国产色视频一区二区三区| 色琪琪av中文字幕一区二区| 欧美精品一区二区三区在线| 无码丰满熟妇| 国产成人免费97在线观看| 欧美成人看片一区二三区图文 | 国产福利姬喷水福利在线观看| 久久国产免费观看精品a片| 国产在线视频www色| 青草青草久热精品视频在线观看| 欧美肥胖老太vidio在线视频| 午夜嘿嘿嘿在线观看| 亚洲老妈激情一区二区三区 | 妺妺窝人体色www看人体| 国产精品无码免费专区午夜 | 影音先锋在线亚洲网站| 777米奇影院狠狠色| 中文字幕亚洲欧美在线不卡 | 特级无码毛片免费视频播放▽| 97人妻免费碰视频碰免| 久久中文字幕人妻熟女| 亚洲日韩成人av无码网站 | 非洲人与性动交ccoo| 中文字幕一二三区波多野结衣| 人人爽人人爽人人片a免费 | 亚洲精品国产精品国自产观看| 国产精品亚洲w码日韩中文 | 无套内谢老熟女| 欧美亚洲日韩国产综合电影| 18禁无遮挡无码国产免费网站| 亚洲欭美日韩颜射在线二| 久久99国产精一区二区三区| 国产精品_九九99久久精品| 欧美中日韩免费观看网站| 99热这里有精品| 又黄又硬又湿又刺激视频免费 | 最近日本mv字幕免费高清完整版| 国产女人水真多18毛片18精品| 色综合久久无码中文字幕 | 日韩精品一区二区三区色欲av| 在线看片免费人成视频久网|