在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CD300LF Antibody

CD300LF Antibody

  • 中文名稱：
    CD300LF兔多克隆抗體
  • 貨號(hào)：
    CSB-PA005859
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HeLa, PC12 cells using CD300f Polyclonal Antibody.
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CD300LF
  • 別名：
    CD300 antigen like family member antibody; CD300 antigen-like family member F antibody; CD300 molecule like family member f antibody; CD300f antibody; CD300LF antibody; CLM antibody; CLM-1 antibody; CLM1 antibody; CLM1_HUMAN antibody; CMRF35-like molecule 1 antibody; IGSF antibody; IgSF13 antibody; Immune receptor expressed on myeloid cells 1 antibody; immune receptor expressed on myeloid cells antibody; immunoglobin superfamily member antibody; Immunoglobulin superfamily member 13 antibody; Immunoglobulin superfamily member antibody; Inhibitory receptor IREM1 antibody; IREM antibody; IREM-1 antibody; IREM1 antibody; Nepmucin antibody; NK inhibitory receptor antibody; NKIR antibody; TREM antibody; triggering receptors expressed on myeloid cells antibody; UNQ3105/PRO10111 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CD300f.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.
  • 基因功能參考文獻(xiàn)：
    1. this study demonstrates the role of CD300f in governing innate immune eosinophil activities in pediatric Crohn's disease patients and in active ulcerative colitis patients PMID: 27118491
    2. findings suggest that two rare heterozygous truncating variations (RPS24 Q191X and CD300LF P261fsX266) are risk candidates for autism spectrum disorder. PMID: 25601189
    3. The data suggest that the neuroprotective role of CD300f would be the result of a complex network of cell interactions. PMID: 21951326
    4. peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling PMID: 22288587
    5. CD300f blocked the activation of cells induced by all TLR ligands PMID: 22043923
    6. Data indicate that CD300F is an active regulator of TLR-mediated macrophage activation through association with SHP-1 involving MyD88 and/or TRIF. PMID: 21536801
    7. Findings indicate that IREM-1 exerted its inhibitory effect on BAFF-medicated signalling through ITIM-mediated regulation of ERK activities in THP-1 cells. PMID: 20646006
    8. IgSF13 was identified from dendritic cells; preferentially expressed in myelo-monocytic cells, including monocytes, monocyte-derived DC and monocyte-related cell lines; may be involved in the negative regulation of specific leukocyte population [IgSF13] PMID: 15184070
    9. a novel inhibitory receptor of the Ig superfamily in myeloid cells. (IREM-1 = immune receptor expressed on myeloid cells-1) PMID: 15549731
    10. reveal a putative functional duality of the IREM-1 myeloid cell receptor PMID: 17202342

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    CD300 family
  • 組織特異性：
    Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocy
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29883

    OMIM: 609807

    KEGG: hsa:146722

    STRING: 9606.ENSP00000327075

    UniGene: Hs.567706



主站蜘蛛池模板： 国产又色又爽又黄的视频在线观看| 少妇又爽又刺激视频| 亚洲va综合va国产产va中文| 国产美熟女乱又伦av果冻传媒 | 亚洲 欧美 日韩 综合aⅴ| 无码色偷偷亚洲国内自拍| 精品日本免费一区二区三区| 奇米影视7777狠狠狠狠影视| 人妻无码第一区二区三区 | 亚洲精品成人av在线观看爽翻天| 精品久久久无码中文字幕| 少妇被粗大的猛烈进出免费视频| 色综合 图片区 小说区| 美女黄网站18禁免费看| 国产精品99精品久久免费| 欧美第一黄网免费网站| 天天影视网天天综合色| 夜夜爱夜鲁夜鲁很鲁| 顶级欧美熟妇xx| 精品视频一区二区三三区四区| 999久久久精品国产消防器材| 亚洲精品久久久口爆吞精| 丰满多毛的大隂户视频| 国产综合有码无码视频在线| 9lporm自拍视频区| 亚洲成av人片在线观看下载| 久久婷婷五月综合色中文字幕| 成人精品一区日本无码网站| 激情久久亚洲小说| 免费午夜男女高清视频| 欧美性猛交xxxx免费看蜜桃| 色先锋资源久久综合5566| 裸体女人高潮毛片| 无码人妻丰满熟妇啪啪欧美| 人妻熟女一二三区夜夜爱| 99re8精品视频热线观看| 久青青视频在线观看久| 性久久久久久| 久久视频这里只精品99| 无码潮喷a片无码高潮视频| 国产麻豆天美果冻无码视频|