在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CD300LF Antibody

  • 中文名稱:
    CD300LF兔多克隆抗體
  • 貨號:
    CSB-PA819470LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA819470LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA819470LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CD300LF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CD300LF
  • 別名:
    CD300 antigen like family member antibody; CD300 antigen-like family member F antibody; CD300 molecule like family member f antibody; CD300f antibody; CD300LF antibody; CLM antibody; CLM-1 antibody; CLM1 antibody; CLM1_HUMAN antibody; CMRF35-like molecule 1 antibody; IGSF antibody; IgSF13 antibody; Immune receptor expressed on myeloid cells 1 antibody; immune receptor expressed on myeloid cells antibody; immunoglobin superfamily member antibody; Immunoglobulin superfamily member 13 antibody; Immunoglobulin superfamily member antibody; Inhibitory receptor IREM1 antibody; IREM antibody; IREM-1 antibody; IREM1 antibody; Nepmucin antibody; NK inhibitory receptor antibody; NKIR antibody; TREM antibody; triggering receptors expressed on myeloid cells antibody; UNQ3105/PRO10111 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human CMRF35-like molecule 1 protein (20-156AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,CD300LF Antibody (CSB-PA819470LA01HU),的標記方式是Non-conjugated。對于CD300LF Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA819470LB01HU CD300LF Antibody, HRP conjugated ELISA
    FITC CSB-PA819470LC01HU CD300LF Antibody, FITC conjugated
    Biotin CSB-PA819470LD01HU CD300LF Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.
  • 基因功能參考文獻:
    1. this study demonstrates the role of CD300f in governing innate immune eosinophil activities in pediatric Crohn's disease patients and in active ulcerative colitis patients PMID: 27118491
    2. findings suggest that two rare heterozygous truncating variations (RPS24 Q191X and CD300LF P261fsX266) are risk candidates for autism spectrum disorder. PMID: 25601189
    3. The data suggest that the neuroprotective role of CD300f would be the result of a complex network of cell interactions. PMID: 21951326
    4. peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling PMID: 22288587
    5. CD300f blocked the activation of cells induced by all TLR ligands PMID: 22043923
    6. Data indicate that CD300F is an active regulator of TLR-mediated macrophage activation through association with SHP-1 involving MyD88 and/or TRIF. PMID: 21536801
    7. Findings indicate that IREM-1 exerted its inhibitory effect on BAFF-medicated signalling through ITIM-mediated regulation of ERK activities in THP-1 cells. PMID: 20646006
    8. IgSF13 was identified from dendritic cells; preferentially expressed in myelo-monocytic cells, including monocytes, monocyte-derived DC and monocyte-related cell lines; may be involved in the negative regulation of specific leukocyte population [IgSF13] PMID: 15184070
    9. a novel inhibitory receptor of the Ig superfamily in myeloid cells. (IREM-1 = immune receptor expressed on myeloid cells-1) PMID: 15549731
    10. reveal a putative functional duality of the IREM-1 myeloid cell receptor PMID: 17202342

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    CD300 family
  • 組織特異性:
    Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocy
  • 數據庫鏈接:

    HGNC: 29883

    OMIM: 609807

    KEGG: hsa:146722

    STRING: 9606.ENSP00000327075

    UniGene: Hs.567706



主站蜘蛛池模板: 97夜夜澡人人爽人人模人人喊| 奶真大水真多小荡货av| 亚洲日韩片无码中文字幕| 热99re久久精品国产首页免费| 黄床片30分钟免费视频教程| 日韩av片无码一区二区不卡电影| 国产乱子伦农村xxxx| 日韩成人极品在线内射3p蜜臀| 人人爽人人爽人人片a| 日日碰日日摸夜夜爽无码| 精品三级久久久久电影网| 草的我好爽视频| 亚洲欧美丝袜精品久久| 四虎亚洲精品成人a在线观看| 成年片色大黄全免费网站久久| 日韩精品电影综合区亚洲| 亚洲aⅴ男人的天堂在线观看| 亚洲日韩精品欧美一区二区一| 国产好爽…又高潮了毛片| 国内精品久久久久影院蜜芽| 国产真实乱对白精彩久久| 丁香五月欧美成人| 日韩精品人妻系列无码专区| 碰超免费人妻中文字幕| 久久ee热这里只有精品| 99久久精品视香蕉蕉| 后入内射国产一区二区| 亚洲精品乱码久久久久久| 精品久久久无码中文字幕一丶| 开心婷婷五月激情综合社区 | 色综合视频一区中文字幕| 国产老熟女狂叫对白| 精品国产精品国产偷麻豆| 97久久久人妻一区精品| 亚洲手机在线人成网站| 2020久热爱精品视频在线观看 | 国产精品99爱免费视频| 熟女性饥渴一区二区三区| av人摸人人人澡人人超碰小说| 亚洲2020天天堂在线观看| 日本乱码伦午夜福利在线|