在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CD300LF Antibody

CD300LF Antibody

  • 中文名稱：
    CD300LF兔多克隆抗體
  • 貨號：
    CSB-PA001445
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using CD300f Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CD300LF
  • 別名：
    CD300 antigen like family member antibody; CD300 antigen-like family member F antibody; CD300 molecule like family member f antibody; CD300f antibody; CD300LF antibody; CLM antibody; CLM-1 antibody; CLM1 antibody; CLM1_HUMAN antibody; CMRF35-like molecule 1 antibody; IGSF antibody; IgSF13 antibody; Immune receptor expressed on myeloid cells 1 antibody; immune receptor expressed on myeloid cells antibody; immunoglobin superfamily member antibody; Immunoglobulin superfamily member 13 antibody; Immunoglobulin superfamily member antibody; Inhibitory receptor IREM1 antibody; IREM antibody; IREM-1 antibody; IREM1 antibody; Nepmucin antibody; NK inhibitory receptor antibody; NKIR antibody; TREM antibody; triggering receptors expressed on myeloid cells antibody; UNQ3105/PRO10111 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CD300f.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.
  • 基因功能參考文獻：
    1. this study demonstrates the role of CD300f in governing innate immune eosinophil activities in pediatric Crohn's disease patients and in active ulcerative colitis patients PMID: 27118491
    2. findings suggest that two rare heterozygous truncating variations (RPS24 Q191X and CD300LF P261fsX266) are risk candidates for autism spectrum disorder. PMID: 25601189
    3. The data suggest that the neuroprotective role of CD300f would be the result of a complex network of cell interactions. PMID: 21951326
    4. peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling PMID: 22288587
    5. CD300f blocked the activation of cells induced by all TLR ligands PMID: 22043923
    6. Data indicate that CD300F is an active regulator of TLR-mediated macrophage activation through association with SHP-1 involving MyD88 and/or TRIF. PMID: 21536801
    7. Findings indicate that IREM-1 exerted its inhibitory effect on BAFF-medicated signalling through ITIM-mediated regulation of ERK activities in THP-1 cells. PMID: 20646006
    8. IgSF13 was identified from dendritic cells; preferentially expressed in myelo-monocytic cells, including monocytes, monocyte-derived DC and monocyte-related cell lines; may be involved in the negative regulation of specific leukocyte population [IgSF13] PMID: 15184070
    9. a novel inhibitory receptor of the Ig superfamily in myeloid cells. (IREM-1 = immune receptor expressed on myeloid cells-1) PMID: 15549731
    10. reveal a putative functional duality of the IREM-1 myeloid cell receptor PMID: 17202342

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    CD300 family
  • 組織特異性：
    Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocy
  • 數據庫鏈接：

    HGNC: 29883

    OMIM: 609807

    KEGG: hsa:146722

    STRING: 9606.ENSP00000327075

    UniGene: Hs.567706



主站蜘蛛池模板： 麻豆成人久久精品二区三区免费 | 久久人人妻人人爽人人爽| 成人爽a毛片在线视频淮北| 欧美中日韩免费观看网站| 国内a∨免费播放| 国产农村乱对白刺激视频| 一本大道久久东京热av| 综合色一色综合久久网| 亚洲成av人片在线播放无码| 无码国产精品一区二区高潮| 欧美日韩一区二区三区自拍| 亚洲欧美日韩愉拍自拍美利坚| 中文字幕av伊人av无码av狼人| 动漫精品视频一区二区三区| 性色欲网站人妻丰满中文久久不卡| 又粗又大又硬毛片免费看| 人妻av无码系列专区移动可看 | 老头把我添高潮了a片| 非洲黑人最猛性xxxx交| 国产激情久久久久影院老熟女免费| 99久久无色码中文字幕人妻蜜柚| 动漫精品中文无码卡通动漫| 中文字幕高清免费日韩视频在线| 国产精品成人久久电影| 欧美videos另类极品| 天堂网www最新版官网| 无码精品人妻一区二区三区湄公河 | 亚洲综合最新无码专区| 日产a一a区二区www| 亚洲熟女乱色综合亚洲小说| 青草内射中出高潮| 高潮爽死抽搐白浆gif视频| 国产午夜精品无码一区二区| 含紧一点h边做边走动免费视频 | 精品一区二区三区影院在线午夜| 国产九九九九九九九a片| 3d动漫精品啪啪一区二区 | 欧美叉叉叉bbb网站| 永久免费无码成人网站| 少妇性荡欲视频| a在线视频v视频|