在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Acyl-protein thioesterase 1 (LYPLA1)

  • 中文名稱:
    人LYPLA1重組蛋白
  • 貨號:
    CSB-YP013268HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人LYPLA1重組蛋白
  • 貨號:
    CSB-EP013268HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人LYPLA1重組蛋白
  • 貨號:
    CSB-EP013268HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人LYPLA1重組蛋白
  • 貨號:
    CSB-BP013268HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人LYPLA1重組蛋白
  • 貨號:
    CSB-MP013268HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    LYPLA1
  • Uniprot No.:
  • 別名:
    Acyl protein thioesterase 1; Acyl-protein thioesterase 1; APT 1; APT-1; APT1; hAPT1; LPL-I; LPL1; LYPA1_HUMAN; LYPLA 1; LYPLA1; Lysophospholipase 1; Lysophospholipase I; Lysophospholipid specific lysophospholipase; LYSOPLA; LysoPLA I
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達(dá)區(qū)域:
    1-230
  • 氨基酸序列
    MCGNNMSTPL PAIVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIRSSHIK YICPHAPVRP VTLNMNVAMP SWFDIIGLSP DSQEDESGIK QAAENIKALI DQEVKNGIPS NRIILGGFSQ GGALSLYTAL TTQQKLAGVT ALSCWLPLRA SFPQGPIGGA NRDISILQCH GDCDPLVPLM FGSLTVEKLK TLVNPANVTF KTYEGMMHSS CQQEMMDVKQ FIDKLLPPID
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Acts as a acyl-protein thioesterase. Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Could also depalmitoylate ADRB2. Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA.
  • 基因功能參考文獻(xiàn):
    1. Data show taht active S-depalmitoylation in mitochondria, in part mediated by acyl-protein thioesterase 1 (APT1) PMID: 29362370
    2. Here, we describe the conserved functions of APT1 and APT2 across organisms and discuss the possibility that these enzymes are members of a larger family of depalmitoylation enzymes. PMID: 25849916
    3. High expression of APT1 is associated with chronic lymphocytic leukemia. PMID: 25670628
    4. identifcation APT1 as one of the thioesterases in the acylation cycle and demonstration that this protein is a cellular target of the inhibitor. PMID: 20418879
    5. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 PMID: 23396970
    6. Serum activity of APT1 may play an important role in determination of the concentration of des-acyl ghrelin in circulation, especially under septic inflammation. PMID: 20685872
    7. Endogenous and overexpressed hAPT1 were mainly localized in the cytosol, while some signals were detected in the plasma membrane, the nuclear membrane and endoplasmic reticulum in HEK293 cells. PMID: 19439193
    8. Results suggest that APT1-regulated depalmitoylation of Galpha(13) might be an important downstream event of miR-138 function. PMID: 19465924

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum.
  • 蛋白家族:
    AB hydrolase superfamily, AB hydrolase 2 family
  • 組織特異性:
    Platelets.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 6737

    OMIM: 605599

    KEGG: hsa:10434

    STRING: 9606.ENSP00000320043

    UniGene: Hs.744046



主站蜘蛛池模板: 肉色欧美久久久久久久免费看| 国产少妇高潮在线观看| 国产成人午夜福利电影在线播放| 欧美情侣性视频| 人人澡人人透人人爽| 国产亚洲精品久久久久久小舞| 最近高清中文在线字幕在线观看1| 日韩精品久久久免费观看| 日本边添边摸边做边爱的网站| 51视频国产精品一区二区| 伊人久久大香线蕉av综合| 欧美40老熟妇色xxxxx| 免费无码精品黄av电影| 欧美巨大黑人极品精男| 国产精品久久自在自线不卡| 亚洲全部无码中文字幕| 国产精品亚洲一区二区三区在线| 久青草无码视频在线观看| 人妻丰满熟妇av无码处处不卡| 亚洲精品久久久久一区二区| 欧洲亚洲精品久久久久| 无码av最新无码av专区| 波多野无码黑人在线播放| 亚洲精品一区二区三区中文字幕| 熟妇丰满多毛的大隂户| 亚洲精品夜夜夜妓女网| 人妻熟妇乱又伦精品视频无广告| 黄网在线观看免费网站| 人人妻一区二区三区| 一区一区三区产品乱码亚洲| 免费网站看sm调教视频| 起碰免费公开97在线视频 | 成人精品一区日本无码网站| 亚洲一区爱区精品无码| 国产热re99久久6国产精品首页| 97免费人妻无码视频| 在线播放免费人成毛片试看| 99c视频色欲在线| 亚洲国产成人精品女人久久久| 久国产精品人妻aⅴ| 在线无码av一区二区三区|