在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LYPLA1 Antibody

LYPLA1 Antibody

  • 中文名稱：
    LYPLA1兔多克隆抗體
  • 貨號：
    CSB-PA076865
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from COLO cells, using LYPLA1 antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LYPLA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LYPLA1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human LYPLA1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a acyl-protein thioesterase. Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Could also depalmitoylate ADRB2. Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA.
  • 基因功能參考文獻：
    1. Data show taht active S-depalmitoylation in mitochondria, in part mediated by acyl-protein thioesterase 1 (APT1) PMID: 29362370
    2. Here, we describe the conserved functions of APT1 and APT2 across organisms and discuss the possibility that these enzymes are members of a larger family of depalmitoylation enzymes. PMID: 25849916
    3. High expression of APT1 is associated with chronic lymphocytic leukemia. PMID: 25670628
    4. identifcation APT1 as one of the thioesterases in the acylation cycle and demonstration that this protein is a cellular target of the inhibitor. PMID: 20418879
    5. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 PMID: 23396970
    6. Serum activity of APT1 may play an important role in determination of the concentration of des-acyl ghrelin in circulation, especially under septic inflammation. PMID: 20685872
    7. Endogenous and overexpressed hAPT1 were mainly localized in the cytosol, while some signals were detected in the plasma membrane, the nuclear membrane and endoplasmic reticulum in HEK293 cells. PMID: 19439193
    8. Results suggest that APT1-regulated depalmitoylation of Galpha(13) might be an important downstream event of miR-138 function. PMID: 19465924

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum.
  • 蛋白家族：
    AB hydrolase superfamily, AB hydrolase 2 family
  • 組織特異性：
    Platelets.
  • 數據庫鏈接：

    HGNC: 6737

    OMIM: 605599

    KEGG: hsa:10434

    STRING: 9606.ENSP00000320043

    UniGene: Hs.744046



主站蜘蛛池模板： 婷婷五月开心亚洲综合在线| 免费无码又爽又刺激高潮视频| 日韩在线一区二区三区免费视频 | 大尺度无遮挡激烈床震网站| 亚洲欧美日韩中文在线制服| 成熟丰满熟妇高潮xxxxx| 国产激情综合五月久久| 亚洲精品久久7777777国产| 在线亚洲97se亚洲综合在线| 亚洲熟妇中文字幕五十中出| 精品黑人一区二区三区| 国产毛片不卡野外视频| 精品无码国产自产在线观看水浒传| 国产成年无码久久久久下载| 欧美变态另类牲交zozo| 国产亚洲精品久久久久久入口| 人妻av乱片av出轨av| 欧美另类videosbestsex日本| 玖玖资源站最稳定网址| 午夜肉伦伦影院| 欧美性猛交xxxx黑人猛交| 少妇人妻邻居| 亚洲中文色欧另类欧美| 人妻少妇久久精品电影| 亚洲女同一区二区| 国产永久免费观看视频| 动漫精品无码h在线观看| 日韩中文无码有码免费视频| 久久99精品久久久久久| 国产日产欧产精品精品推荐免费| 欧美老妇疯狂xxxxbbbb| 久久精品国产亚洲7777| 久久www成人_看片免费不卡| 亚洲中文无码永久免| 亚洲精品久久久久久中文传媒| b站永久免费看片大全| 亚洲国产欧美不卡在线观看| 久久亚洲国产精品五月天婷| 国产色无码精品视频国产| 69成人免费视频无码专区| 亚洲国产成人久久一区|