在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LYPLA1 Antibody

LYPLA1 Antibody

  • 中文名稱：
    LYPLA1兔多克隆抗體
  • 貨號：
    CSB-PA003181
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using LYPLA1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    LYPLA1
  • 別名：
    Acyl protein thioesterase 1 antibody; Acyl-protein thioesterase 1 antibody; APT 1 antibody; APT-1 antibody; APT1 antibody; hAPT1 antibody; LPL-I antibody; LPL1 antibody; LYPA1_HUMAN antibody; LYPLA 1 antibody; LYPLA1 antibody; Lysophospholipase 1 antibody; Lysophospholipase I antibody; Lysophospholipid specific lysophospholipase antibody; LYSOPLA antibody; LysoPLA I antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human LYPLA1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a acyl-protein thioesterase. Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Could also depalmitoylate ADRB2. Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA.
  • 基因功能參考文獻：
    1. Data show taht active S-depalmitoylation in mitochondria, in part mediated by acyl-protein thioesterase 1 (APT1) PMID: 29362370
    2. Here, we describe the conserved functions of APT1 and APT2 across organisms and discuss the possibility that these enzymes are members of a larger family of depalmitoylation enzymes. PMID: 25849916
    3. High expression of APT1 is associated with chronic lymphocytic leukemia. PMID: 25670628
    4. identifcation APT1 as one of the thioesterases in the acylation cycle and demonstration that this protein is a cellular target of the inhibitor. PMID: 20418879
    5. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 PMID: 23396970
    6. Serum activity of APT1 may play an important role in determination of the concentration of des-acyl ghrelin in circulation, especially under septic inflammation. PMID: 20685872
    7. Endogenous and overexpressed hAPT1 were mainly localized in the cytosol, while some signals were detected in the plasma membrane, the nuclear membrane and endoplasmic reticulum in HEK293 cells. PMID: 19439193
    8. Results suggest that APT1-regulated depalmitoylation of Galpha(13) might be an important downstream event of miR-138 function. PMID: 19465924

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum.
  • 蛋白家族：
    AB hydrolase superfamily, AB hydrolase 2 family
  • 組織特異性：
    Platelets.
  • 數據庫鏈接：

    HGNC: 6737

    OMIM: 605599

    KEGG: hsa:10434

    STRING: 9606.ENSP00000320043

    UniGene: Hs.744046



主站蜘蛛池模板： 自慰无码一区二区三区| 国产成人片无码免费视频软件| 中文字幕大看蕉在线观看| 亚洲精品一区久久久久久| 国产天堂亚洲国产碰碰| 国产看真人毛片爱做a片| 成在人线av无码免费高潮水老板| 午夜免费啪视频在线观看区| 国产精品久久久一区二区三区| 国产精品无码免费播放| 亚洲日韩精品一区二区三区无码| 欧美牲交视频免费观看| 久久久99久久久国产自输拍| 成在人线av无码免费| 男女车车的车车网站w98免费| 宅宅午夜无码一区二区三区| 精品国偷自产在线视频| 亚洲日韩v无码中文字幕| 午夜a理论片在线播放| 亚洲成成品网站源码中国有限公司 | 内射精品无码中文字幕| 国产产区一二三产区区别在线 | 日产精品1区2区3区| 亚洲娇小与黑人巨大交| 亚洲人精品午夜射精日韩| 人与狗精品aa毛片| 亚洲午夜成人精品无码| 国内自拍视频一区二区三区| 曰韩少妇内射免费播放| 蜜臀性色av免费| 99偷拍视频精品一区二区| 国产精品sp调教打屁股| 国产精品自在自线视频| 狠日狠干日日射| 国产精品一品二区三区的使用体验| 亚洲a∨国产av综合av| 狠狠色色综合站| 午夜成人鲁丝片午夜精品| 免费观看性行为视频的网站| 国产亚洲精品电影网站在线观看| 岛国av动作片在线观看|