在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LYPLA1 Antibody

LYPLA1 Antibody

  • 中文名稱：
    LYPLA1兔多克隆抗體
  • 貨號：
    CSB-PA003181
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using LYPLA1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    LYPLA1
  • 別名：
    Acyl protein thioesterase 1 antibody; Acyl-protein thioesterase 1 antibody; APT 1 antibody; APT-1 antibody; APT1 antibody; hAPT1 antibody; LPL-I antibody; LPL1 antibody; LYPA1_HUMAN antibody; LYPLA 1 antibody; LYPLA1 antibody; Lysophospholipase 1 antibody; Lysophospholipase I antibody; Lysophospholipid specific lysophospholipase antibody; LYSOPLA antibody; LysoPLA I antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human LYPLA1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a acyl-protein thioesterase. Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Could also depalmitoylate ADRB2. Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA.
  • 基因功能參考文獻：
    1. Data show taht active S-depalmitoylation in mitochondria, in part mediated by acyl-protein thioesterase 1 (APT1) PMID: 29362370
    2. Here, we describe the conserved functions of APT1 and APT2 across organisms and discuss the possibility that these enzymes are members of a larger family of depalmitoylation enzymes. PMID: 25849916
    3. High expression of APT1 is associated with chronic lymphocytic leukemia. PMID: 25670628
    4. identifcation APT1 as one of the thioesterases in the acylation cycle and demonstration that this protein is a cellular target of the inhibitor. PMID: 20418879
    5. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 PMID: 23396970
    6. Serum activity of APT1 may play an important role in determination of the concentration of des-acyl ghrelin in circulation, especially under septic inflammation. PMID: 20685872
    7. Endogenous and overexpressed hAPT1 were mainly localized in the cytosol, while some signals were detected in the plasma membrane, the nuclear membrane and endoplasmic reticulum in HEK293 cells. PMID: 19439193
    8. Results suggest that APT1-regulated depalmitoylation of Galpha(13) might be an important downstream event of miR-138 function. PMID: 19465924

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum.
  • 蛋白家族：
    AB hydrolase superfamily, AB hydrolase 2 family
  • 組織特異性：
    Platelets.
  • 數據庫鏈接：

    HGNC: 6737

    OMIM: 605599

    KEGG: hsa:10434

    STRING: 9606.ENSP00000320043

    UniGene: Hs.744046



主站蜘蛛池模板： av在线亚洲欧洲日产一区二区| 大陆国语对白国产av片| 中文字幕无线码一区二区| 国内精品久久久久影院嫩草| 国产精品免费观看调教网| 亚洲国产欧美在线人成aaaa| 窝窝午夜理论片影院| 国产高清视频一区三区| 99九九99九九视频精品| 精品人成视频免费国产| 男受被做哭激烈娇喘gv视频| 国产精品人人妻人人爽| 日韩人妻无码精品久久| 自拍偷自拍亚洲精品牛影院| 国产自偷自偷免费一区| 西西人体大胆瓣开下部毛茸茸| 超caopor在线公开视频| 亚洲高清偷拍一区二区三区| 脱了美女内裤猛烈进入gif| 色婷婷五月综合久久| 国产av国片精品一区二区| 国内精品久久久久久不卡影院| 丰满少妇弄高潮了www| 少妇精油按摩av无码中字| 国产午夜人做人免费视频网站| 蜜桃视频在线观看免费视频网站www| 日本大片免a费观看视频| 狼友av永久网站免费观看孕交 | 久久综合狠狠综合久久激情| 天躁夜夜躁狼狠躁| 天天躁日日躁狠狠躁2018| 亚洲 卡通 欧美 制服 中文| 亚洲精品www久久久| 囯产精品一品二区三区| 免费国产成人高清在线观看网站| 久久中文字幕人妻熟女| 亚洲啪av永久无码精品放毛片| 无人区码一码二码三码区别新月| 小污女导航福利入口| 无码人妻久久久一区二区三区 | 国产精品青青在线麻豆|