在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1)

Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1)

  • 中文名稱：
    人SUPV3L1重組蛋白
  • 貨號：
    CSB-YP814232HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SUPV3L1重組蛋白
  • 貨號：
    CSB-EP814232HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SUPV3L1重組蛋白
  • 貨號：
    CSB-EP814232HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SUPV3L1重組蛋白
  • 貨號：
    CSB-BP814232HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SUPV3L1重組蛋白
  • 貨號：
    CSB-MP814232HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SUPV3L1
  • Uniprot No.：
  • 別名：
    6330443E10Rik ; ATP dependent RNA helicase SUPV3L1; mitochondrial; ATP-dependent RNA helicase SUPV3L1; EC 3.6.1.; MGC109049; mitochondrial; OTTHUMP00000019719; S. Cerevisiae suppressor of var 1 3 like 1; suppressor of var1 (S.cerevisiae) 3 like 1; Suppressor of var1 3 like 1 (S. cerevisiae); Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3); Suppressor of var1 3 like 1; Suppressor of var1 3 like protein 1; Suppressor of var1 3-like protein 1; SUPV 3 L 1; SUPV3L1; SUV 3; SUV 3 L 1; SUV3; SUV3 like protein 1; SUV3-like protein 1; SUV3_HUMAN; SUV3L1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    23-786
  • 氨基酸序列
    AICSALRP HFGPFPGVLG QVSVLATASS SASGGSKIPN TSLFVPLTVK PQGPSADGDV GAELTRPLDK NEVKKVLDKF YKRKEIQKLG ADYGLDARLF HQAFISFRNY IMQSHSLDVD IHIVLNDICF GAAHADDLFP FFLRHAKQIF PVLDCKDDLR KISDLRIPPN WYPDARAMQR KIIFHSGPTN SGKTYHAIQK YFSAKSGVYC GPLKLLAHEI FEKSNAAGVP CDLVTGEERV TVQPNGKQAS HVSCTVEMCS VTTPYEVAVI DEIQMIRDPA RGWAWTRALL GLCAEEVHLC GEPAAIDLVM ELMYTTGEEV EVRDYKRLTP ISVLDHALES LDNLRPGDCI VCFSKNDIYS VSRQIEIRGL ESAVIYGSLP PGTKLAQAKK FNDPNDPCKI LVATDAIGMG LNLSIRRIIF YSLIKPSINE KGERELEPIT TSQALQIAGR AGRFSSRFKE GEVTTMNHED LSLLKEILKR PVDPIRAAGL HPTAEQIEMF AYHLPDATLS NLIDIFVDFS QVDGQYFVCN MDDFKFSAEL IQHIPLSLRV RYVFCTAPIN KKQPFVCSSL LQFARQYSRN EPLTFAWLRR YIKWPLLPPK NIKDLMDLEA VHDVLDLYLW LSYRFMDMFP DASLIRDLQK ELDGIIQDGV HNITKLIKMS ETHKLLNLEG FPSGSQSRLS GTLKSQARRT RGTKALGSKA TEPPSPDAGE LSLASRLVQQ GLLTPDMLKQ LEKEWMTQQT EHNKEKTESG THPKGTRRKK KEPDSD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
  • 基因功能參考文獻：
    1. the nucleolar- associated human SUV3 protein is an important factor in regulation of the cell cycle. PMID: 28291845
    2. the capacity of hSuv3 DNA unwinding activity might be sensitive to the local availability of specific inorganic cofactors PMID: 25446650
    3. SUV3 bridges PNPase and mtPAP to form a transient complex in modulating mt-mRNA poly(A) tail length depending on the mitochondrial matrix Pi level. PMID: 24770417
    4. Interaction between PNPase and hSuv3 is essential for efficient mitochondrial RNA degradation. PMID: 23221631
    5. The hSuv3p activity was found to be necessary in the regulation of stability of mature, properly formed mRNAs and for removal of the noncoding processing intermediates transcribed from both H and L-strands. PMID: 19864255
    6. Localisation of hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA. PMID: 12466530
    7. Human SUV3 is an ATP-dependent multiple-substrate helicase; in addition to dsRNA and dsDNA unwinding activity, SUV3-70 and SUV3-83 can unwind heteroduplexes of RNA and DNA. PMID: 15096047
    8. data suggest that hSUV3 is a housekeeping gene with an enhancer region & regulatory elements in basal promoter PMID: 15919122
    9. Suv3 protein interacts with HBXIP, previously identified as a cofactor of survivin in suppression of apoptosis PMID: 16176273
    10. Down-regulation of hSUV3 results in cell cycle perturbations and in apoptosis, which is both AIF- and caspase-dependent, and proceeds with the induction of p53. PMID: 17352692
    11. Human SUV3 protein interacts with human WRN and BLM helicases. Silencing of the SUV3 gene in the human cell line HeLa resulted in elevation of homologous recombination as measured by the frequency of sister chromatid exchange during mitotic cell division. PMID: 17961633
    12. SUV3 is essential for maintaining proper mitochondrial function, likely through a conserved role in mitochondrial RNA regulation. PMID: 18678873
    13. The complex of hSUV3-hPNPase is an integral entity for efficient degradation of structured RNA and may be the long sought RNA-degrading complex in the mammalian mitochondria. PMID: 19509288

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
  • 蛋白家族：
    Helicase family
  • 組織特異性：
    Broadly expressed.
  • 數據庫鏈接：

    HGNC: 11471

    OMIM: 605122

    KEGG: hsa:6832

    STRING: 9606.ENSP00000352678

    UniGene: Hs.106469



主站蜘蛛池模板： 久久亚洲精品成人av| а√中文在线资源库| 国产精品一区二区av| 华人在线亚洲欧美精品| 麻豆自媒体 一区 二区| 精品久久久久久无码人妻vr| 久久大香国产成人av| 国产成年无码久久久久下载| 久久精品a亚洲国产v高清不卡| 久久婷婷久久一区二区三区| 曰韩精品无码一区二区视频| 亚洲精品无码成人av电影网| 在线视频观看免费视频18| 欧洲乱码伦视频免费| 久久精品中文字幕大胸| 国产美女裸体丝袜喷水视频 | 国产毛片精品av一区二区| 亚洲无日韩码精品| 18禁成年无码免费网站| 在线 | 一区二区三区四区| 精品久久久久久成人av| 日韩新无码精品毛片| 亚洲精品无码乱码成人| 亚洲色爱图小说专区| 天天摸天天碰天天添| 四虎永久在线精品免费网址 | 国内精品九九久久精品| 中国女人内射6xxxxx| 亚洲精品无码av中文字幕电影网站 | 日本高清二区视频久二区| 青青草原综合久久大伊人精品| 国产一区二区| 亚洲红杏成在人线免费视频| 亚洲精品av一区在线观看| 亚洲国产精品久久久久久久| 色两性网欧美| 午夜福利精品亚洲不卡| 亚洲 小说 欧美 另类 社区| 狠狠综合久久综合88亚洲| 竹菊影视欧美日韩一区二区三区四区五区 | 国产成人无码av一区二区|