在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SUPV3L1 Antibody, FITC conjugated

  • 中文名稱:
    SUPV3L1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA814232LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SUPV3L1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SUPV3L1
  • 別名:
    6330443E10Rik antibody; ATP dependent RNA helicase SUPV3L1; mitochondrial antibody; ATP-dependent RNA helicase SUPV3L1 antibody; EC 3.6.1. antibody; MGC109049 antibody; mitochondrial antibody; OTTHUMP00000019719 antibody; S. Cerevisiae suppressor of var 1 3 like 1 antibody; suppressor of var1 (S.cerevisiae) 3 like 1 antibody; Suppressor of var1 3 like 1 (S. cerevisiae) antibody; Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3) antibody; Suppressor of var1 3 like 1 antibody; Suppressor of var1 3 like protein 1 antibody; Suppressor of var1 3-like protein 1 antibody; SUPV 3 L 1 antibody; SUPV3L1 antibody; SUV 3 antibody; SUV 3 L 1 antibody; SUV3 antibody; SUV3 like protein 1 antibody; SUV3-like protein 1 antibody; SUV3_HUMAN antibody; SUV3L1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial protein (499-786AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
  • 基因功能參考文獻:
    1. the nucleolar- associated human SUV3 protein is an important factor in regulation of the cell cycle. PMID: 28291845
    2. the capacity of hSuv3 DNA unwinding activity might be sensitive to the local availability of specific inorganic cofactors PMID: 25446650
    3. SUV3 bridges PNPase and mtPAP to form a transient complex in modulating mt-mRNA poly(A) tail length depending on the mitochondrial matrix Pi level. PMID: 24770417
    4. Interaction between PNPase and hSuv3 is essential for efficient mitochondrial RNA degradation. PMID: 23221631
    5. The hSuv3p activity was found to be necessary in the regulation of stability of mature, properly formed mRNAs and for removal of the noncoding processing intermediates transcribed from both H and L-strands. PMID: 19864255
    6. Localisation of hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA. PMID: 12466530
    7. Human SUV3 is an ATP-dependent multiple-substrate helicase; in addition to dsRNA and dsDNA unwinding activity, SUV3-70 and SUV3-83 can unwind heteroduplexes of RNA and DNA. PMID: 15096047
    8. data suggest that hSUV3 is a housekeeping gene with an enhancer region & regulatory elements in basal promoter PMID: 15919122
    9. Suv3 protein interacts with HBXIP, previously identified as a cofactor of survivin in suppression of apoptosis PMID: 16176273
    10. Down-regulation of hSUV3 results in cell cycle perturbations and in apoptosis, which is both AIF- and caspase-dependent, and proceeds with the induction of p53. PMID: 17352692
    11. Human SUV3 protein interacts with human WRN and BLM helicases. Silencing of the SUV3 gene in the human cell line HeLa resulted in elevation of homologous recombination as measured by the frequency of sister chromatid exchange during mitotic cell division. PMID: 17961633
    12. SUV3 is essential for maintaining proper mitochondrial function, likely through a conserved role in mitochondrial RNA regulation. PMID: 18678873
    13. The complex of hSUV3-hPNPase is an integral entity for efficient degradation of structured RNA and may be the long sought RNA-degrading complex in the mammalian mitochondria. PMID: 19509288

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
  • 蛋白家族:
    Helicase family
  • 組織特異性:
    Broadly expressed.
  • 數據庫鏈接:

    HGNC: 11471

    OMIM: 605122

    KEGG: hsa:6832

    STRING: 9606.ENSP00000352678

    UniGene: Hs.106469



主站蜘蛛池模板: av中文字幕无码免费看| 免费看成人午夜福利专区| 99精品无码一区二区| 男人用嘴添女人私密视频| 欧美成妇人吹潮在线播放| 国精产品48x国精产品| 中国6一12呦女精品| 亚洲成av人片在线观看| 插鸡网站在线播放免费观看| 97色成人综合网站| 久久精品成人亚洲另类欧美| 国产成人精品优优av| 蜜臀亚洲精品国产aⅴ综合第一| 日本欧美一区二区三区高清| 少妇大叫好爽受不了午夜视频 | 狠狠色婷婷久久综合频道毛片| 国产精品久久久久久吹潮| 精品国产一区二区三区四区精华液| 超级大爆乳奶牛被调教出奶水| 久久久久免费看黄a片app| 人妻少妇一区二区三区| 97在线成人国产在线视频| 国产精品无码翘臀在线看 | 国产亚洲曝欧美不卡精品| 吃奶呻吟打开双腿做受动态图| 精品国产一区二区三区色欲| 亚洲kkk4444在线观看| 欧美人与性动交α欧美精品| 欧妇女乱妇女乱视频| 午夜福利电影网站鲁片大全| 国产亚洲精aa在线观看| 久久综合九色综合欧美98 | 日韩网红少妇无码视频香港 | 国产av无码专区亚洲草草| 男人靠女人的免费视频| 日韩成人无码一区二区三区| 在线观看国产成人av天堂 | 久热这里只有精品12| a一区二区三区乱码在线 | 欧洲| 欲求不满邻居的爆乳在线播放| 韩国国内大量揄拍精品视频|