在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SUPV3L1 Antibody, HRP conjugated

SUPV3L1 Antibody, HRP conjugated

  • 中文名稱：
    SUPV3L1兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA814232LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SUPV3L1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SUPV3L1
  • 別名：
    6330443E10Rik antibody; ATP dependent RNA helicase SUPV3L1; mitochondrial antibody; ATP-dependent RNA helicase SUPV3L1 antibody; EC 3.6.1. antibody; MGC109049 antibody; mitochondrial antibody; OTTHUMP00000019719 antibody; S. Cerevisiae suppressor of var 1 3 like 1 antibody; suppressor of var1 (S.cerevisiae) 3 like 1 antibody; Suppressor of var1 3 like 1 (S. cerevisiae) antibody; Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3) antibody; Suppressor of var1 3 like 1 antibody; Suppressor of var1 3 like protein 1 antibody; Suppressor of var1 3-like protein 1 antibody; SUPV 3 L 1 antibody; SUPV3L1 antibody; SUV 3 antibody; SUV 3 L 1 antibody; SUV3 antibody; SUV3 like protein 1 antibody; SUV3-like protein 1 antibody; SUV3_HUMAN antibody; SUV3L1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial protein (499-786AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
  • 基因功能參考文獻：
    1. the nucleolar- associated human SUV3 protein is an important factor in regulation of the cell cycle. PMID: 28291845
    2. the capacity of hSuv3 DNA unwinding activity might be sensitive to the local availability of specific inorganic cofactors PMID: 25446650
    3. SUV3 bridges PNPase and mtPAP to form a transient complex in modulating mt-mRNA poly(A) tail length depending on the mitochondrial matrix Pi level. PMID: 24770417
    4. Interaction between PNPase and hSuv3 is essential for efficient mitochondrial RNA degradation. PMID: 23221631
    5. The hSuv3p activity was found to be necessary in the regulation of stability of mature, properly formed mRNAs and for removal of the noncoding processing intermediates transcribed from both H and L-strands. PMID: 19864255
    6. Localisation of hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA. PMID: 12466530
    7. Human SUV3 is an ATP-dependent multiple-substrate helicase; in addition to dsRNA and dsDNA unwinding activity, SUV3-70 and SUV3-83 can unwind heteroduplexes of RNA and DNA. PMID: 15096047
    8. data suggest that hSUV3 is a housekeeping gene with an enhancer region & regulatory elements in basal promoter PMID: 15919122
    9. Suv3 protein interacts with HBXIP, previously identified as a cofactor of survivin in suppression of apoptosis PMID: 16176273
    10. Down-regulation of hSUV3 results in cell cycle perturbations and in apoptosis, which is both AIF- and caspase-dependent, and proceeds with the induction of p53. PMID: 17352692
    11. Human SUV3 protein interacts with human WRN and BLM helicases. Silencing of the SUV3 gene in the human cell line HeLa resulted in elevation of homologous recombination as measured by the frequency of sister chromatid exchange during mitotic cell division. PMID: 17961633
    12. SUV3 is essential for maintaining proper mitochondrial function, likely through a conserved role in mitochondrial RNA regulation. PMID: 18678873
    13. The complex of hSUV3-hPNPase is an integral entity for efficient degradation of structured RNA and may be the long sought RNA-degrading complex in the mammalian mitochondria. PMID: 19509288

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
  • 蛋白家族：
    Helicase family
  • 組織特異性：
    Broadly expressed.
  • 數據庫鏈接：

    HGNC: 11471

    OMIM: 605122

    KEGG: hsa:6832

    STRING: 9606.ENSP00000352678

    UniGene: Hs.106469



主站蜘蛛池模板： 扒开双腿疯狂进出爽爽爽视频| 精品四虎国产在免费观看| 国产情侣激情在线视频| 国自产拍偷拍精品啪啪av| 国产精品无码v在线观看| 国产精品一区二区久久| 亚洲综合色噜噜狠狠网站超清| 久久理论片午夜琪琪电影网| 九九精品99久久久香蕉| 亚欧美无遮挡hd高清在线视频| 日本又黄又潮娇喘视频| 国产精品av一区二区三区不卡蜜| 国产色婷婷亚洲99精品小说 | 77777亚洲午夜久久多人| 免费精品国偷自产在线在线| 国产欧美在线亚洲一区| 草草地址线路①屁屁影院成人| 精品人妻一区二区三区四区| 狠狠久久久久综合成人影院| 很黄很黄的曰批视频| 强行糟蹋人妻hd中文字幕| 精品久久久久久无码免费| 色惰日本视频网站www| 国产电影一区二区三区| 亚洲成av人片一区二区密柚| 2021久久精品国产99国产精品 | 天堂va欧美va亚洲va好看va| 日本又黄又爽又色又刺激的视频| 色135综合网| 亚洲国产成人精品一区刚刚| 中文字幕+乱码+中文字幕一区| 婷婷色香五月综合激激情| 亚洲小说区图片区另类春色| 一本色道久久综合亚州精品蜜桃| 中文字幕久热精品视频在线| 亚洲中文字幕无码爆乳av| 亚洲国产精品成人精品无码区在线| 亚洲精品在看在线观看| 亚洲国产精品美女久久久久| 人成午夜大片免费视频77777| 亚洲人成无码网www动漫|