在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SUPV3L1 Antibody, HRP conjugated

SUPV3L1 Antibody, HRP conjugated

  • 中文名稱：
    SUPV3L1兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA814232LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SUPV3L1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SUPV3L1
  • 別名：
    6330443E10Rik antibody; ATP dependent RNA helicase SUPV3L1; mitochondrial antibody; ATP-dependent RNA helicase SUPV3L1 antibody; EC 3.6.1. antibody; MGC109049 antibody; mitochondrial antibody; OTTHUMP00000019719 antibody; S. Cerevisiae suppressor of var 1 3 like 1 antibody; suppressor of var1 (S.cerevisiae) 3 like 1 antibody; Suppressor of var1 3 like 1 (S. cerevisiae) antibody; Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3) antibody; Suppressor of var1 3 like 1 antibody; Suppressor of var1 3 like protein 1 antibody; Suppressor of var1 3-like protein 1 antibody; SUPV 3 L 1 antibody; SUPV3L1 antibody; SUV 3 antibody; SUV 3 L 1 antibody; SUV3 antibody; SUV3 like protein 1 antibody; SUV3-like protein 1 antibody; SUV3_HUMAN antibody; SUV3L1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial protein (499-786AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
  • 基因功能參考文獻：
    1. the nucleolar- associated human SUV3 protein is an important factor in regulation of the cell cycle. PMID: 28291845
    2. the capacity of hSuv3 DNA unwinding activity might be sensitive to the local availability of specific inorganic cofactors PMID: 25446650
    3. SUV3 bridges PNPase and mtPAP to form a transient complex in modulating mt-mRNA poly(A) tail length depending on the mitochondrial matrix Pi level. PMID: 24770417
    4. Interaction between PNPase and hSuv3 is essential for efficient mitochondrial RNA degradation. PMID: 23221631
    5. The hSuv3p activity was found to be necessary in the regulation of stability of mature, properly formed mRNAs and for removal of the noncoding processing intermediates transcribed from both H and L-strands. PMID: 19864255
    6. Localisation of hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA. PMID: 12466530
    7. Human SUV3 is an ATP-dependent multiple-substrate helicase; in addition to dsRNA and dsDNA unwinding activity, SUV3-70 and SUV3-83 can unwind heteroduplexes of RNA and DNA. PMID: 15096047
    8. data suggest that hSUV3 is a housekeeping gene with an enhancer region & regulatory elements in basal promoter PMID: 15919122
    9. Suv3 protein interacts with HBXIP, previously identified as a cofactor of survivin in suppression of apoptosis PMID: 16176273
    10. Down-regulation of hSUV3 results in cell cycle perturbations and in apoptosis, which is both AIF- and caspase-dependent, and proceeds with the induction of p53. PMID: 17352692
    11. Human SUV3 protein interacts with human WRN and BLM helicases. Silencing of the SUV3 gene in the human cell line HeLa resulted in elevation of homologous recombination as measured by the frequency of sister chromatid exchange during mitotic cell division. PMID: 17961633
    12. SUV3 is essential for maintaining proper mitochondrial function, likely through a conserved role in mitochondrial RNA regulation. PMID: 18678873
    13. The complex of hSUV3-hPNPase is an integral entity for efficient degradation of structured RNA and may be the long sought RNA-degrading complex in the mammalian mitochondria. PMID: 19509288

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
  • 蛋白家族：
    Helicase family
  • 組織特異性：
    Broadly expressed.
  • 數據庫鏈接：

    HGNC: 11471

    OMIM: 605122

    KEGG: hsa:6832

    STRING: 9606.ENSP00000352678

    UniGene: Hs.106469



主站蜘蛛池模板： 日韩精品无码一区二区中文字幕| 日韩去日本高清在线| 四虎亚洲欧美成人网站| 亚洲人成无码网www电影榴莲| 亚洲国产精品无码久久久蜜芽| 欧美视频网站www色| 日本丰满熟妇hd| 野花社区视频www官网| 日韩精品一区二区在线观看| 久久久受www免费人成| 亚洲国内精品自在线影院| 亚洲桃色天堂网| 婷婷综合缴情亚洲狠狠小说| 麻花传媒在线观看免费| 午夜成人亚洲理伦片在线观看 | 成人性做爰aaa片免费看曹查理| 中国孕妇变态孕交xxxx| 一性一交一口添一摸视频| 2021精品国夜夜天天拍拍| 欧美性video高清精品| 免费无码专区在线视频| 亚洲无av在线中文字幕| 国产精品视频免费播放| 国产午夜大地久久| 一本天堂v无码亚洲道久久| 玖玖资源站无码专区| 久久久亚洲精品一区二区三区浴池| 蜜芽久久人人超碰爱香蕉| 亚洲中文字幕乱码电影| 欧美午夜片欧美片在线观看| 无码av最新高清无码专区| 韩国三级丰满少妇高潮| 337p西西人体大胆瓣开下部| 伊人久久大香线蕉在观看| 精品人妻伦一二三区久久aaa片| 日日噜狠狠噜天天噜av| 亚洲精品美女久久7777777| 日本一二免费不卡区 | 暖暖的在线观看日本社区| 亚洲精品无码专区在线| 欧美成人一区二免费视频软件|