在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human 60S ribosomal protein L3 (RPL3)

  • 中文名稱:
    人RPL3重組蛋白
  • 貨號:
    CSB-YP020224HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人RPL3重組蛋白
  • 貨號:
    CSB-EP020224HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人RPL3重組蛋白
  • 貨號:
    CSB-EP020224HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人RPL3重組蛋白
  • 貨號:
    CSB-BP020224HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人RPL3重組蛋白
  • 貨號:
    CSB-MP020224HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    RPL3
  • Uniprot No.:
  • 別名:
    60S ribosomal protein L3; HIV-1 TAR RNA-binding protein B; HIV1 TAR RNA binding protein B; MGC103388; MGC104284; MGC72934; Ribosomal protein L3; Ribosomal protein L3, isoform a; RL3_HUMAN; rpl3; TARBP B; TARBP-B
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    2-403
  • 氨基酸序列
    SHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGIV GYVETPRGLR TFKTVFAEHI SDECKRRFYK NWHKSKKKAF TKYCKKWQDE DGKKQLEKDF SSMKKYCQVI RVIAHTQMRL LPLRQKKAHL MEIQVNGGTV AEKLDWARER LEQQVPVNQV FGQDEMIDVI GVTKGKGYKG VTSRWHTKKL PRKTHRGLRK VACIGAWHPA RVAFSVARAG QKGYHHRTEI NKKIYKIGQG YLIKDGKLIK NNASTDYDLS DKSINPLGGF VHYGEVTNDF VMLKGCVVGT KKRVLTLRKS LLVQTKRRAL EKIDLKFIDT TSKFGHGRFQ TMEEKKAFMG PLKKDRIAKE EGA
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
  • 基因功能參考文獻(xiàn):
    1. The sensitivity of p53 null colon cancer cells to 5-FU can be enhanced using proapoptotic rpL3 gene. PMID: 27835895
    2. nucleolar stress induced by 5-fluorouracil in colon cancer cells devoid of p53 leads to the activation of ribosomal protein L3 as proapoptotic factor PMID: 27385096
    3. We found that uL3 down-regulation correlates positively with multidrug resistance. Restoration of the uL3 protein level re-sensitized the resistant cells to the drug by regulating the reactive oxygen species (ROS) levels, glutathione content, glutamate release, and cystine uptake. PMID: 28273808
    4. rpL3 participates in the cell response to chemotherapy acting as a critical regulator of cell cycle, apoptosis and DNA repair, by modulating p21 expression PMID: 25473889
    5. The rpL3 is able to modulate the protein amounts of p21 through a novel pathway independent from p53 involving Sp1 and NPM. PMID: 23255119
    6. NPM and KHSRP are two newly identified proteins involved in the regulation of rpL3 gene expression via alternative pre-mRNA splicing. PMID: 21705779
    7. working model in which rpL3 recruits hnRNP H1 and, through cooperation with other splicing factors, promotes selection of the alternative splice site PMID: 20100605

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus, nucleolus. Cytoplasm.
  • 蛋白家族:
    Universal ribosomal protein uL3 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10332

    OMIM: 604163

    KEGG: hsa:6122

    STRING: 9606.ENSP00000346001

    UniGene: Hs.119598



主站蜘蛛池模板: 护士的小嫩嫩好紧好爽| 毛片内射久久久一区| 国内揄拍高清国内精品对白| 怡红院a∨人人爰人人爽| 久久久久久久女国产乱让韩| 国产亚洲精品久久久久久国| 中文字幕人妻第一区| 国产98在线 | 免费、| 亚洲国产精品国自产拍av| 久久成人影院精品99| 最美女人体内射精一区二区| 亚洲色大成网站www国产| 免费观看羞羞视频网站| 漂亮人妻熟睡中被公侵犯中文版| 国产农村黄aaaaa特黄av毛片| 国产成av人片在线观看无码| 国产精品亚洲一区二区| 熟女少妇在线视频播放| 亚洲精品无码你懂的| 春色校园亚洲愉拍自拍| 农民人伦一区二区三区| 日韩中文字幕区一区有砖一区| 男人猛戳女人30分钟视频大全| 狠狠色丁香久久婷婷综合蜜芽五月| 国产精品99精品久久免费| 亚洲第一综合天堂另类专| 新普新京亚洲欧美日韩国产| 爽到高潮无码视频在线观看| 无码福利日韩神码福利片| 国产美足白丝榨精在线观看sm| 777午夜福利理伦电影网| 国产精品激情| 成人免费777777| 麻豆果冻精东九一传媒mv| 国产精品玩偶在线观看| 一本一本久久aa综合精品| 亚洲一本大道av久在线播放| 国精产品69永久中国有限 | 东京热加勒比无码少妇| 中文人妻无码一区二区三区| 成人啪精品视频网站午夜|