在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RPL3 Antibody

  • 中文名稱:
    RPL3兔多克隆抗體
  • 貨號:
    CSB-PA283324
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HT-29 cells, using RPL3 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using RPL3 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RPL3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RPL3
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from internal of Human RPL3.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
  • 基因功能參考文獻:
    1. The sensitivity of p53 null colon cancer cells to 5-FU can be enhanced using proapoptotic rpL3 gene. PMID: 27835895
    2. nucleolar stress induced by 5-fluorouracil in colon cancer cells devoid of p53 leads to the activation of ribosomal protein L3 as proapoptotic factor PMID: 27385096
    3. We found that uL3 down-regulation correlates positively with multidrug resistance. Restoration of the uL3 protein level re-sensitized the resistant cells to the drug by regulating the reactive oxygen species (ROS) levels, glutathione content, glutamate release, and cystine uptake. PMID: 28273808
    4. rpL3 participates in the cell response to chemotherapy acting as a critical regulator of cell cycle, apoptosis and DNA repair, by modulating p21 expression PMID: 25473889
    5. The rpL3 is able to modulate the protein amounts of p21 through a novel pathway independent from p53 involving Sp1 and NPM. PMID: 23255119
    6. NPM and KHSRP are two newly identified proteins involved in the regulation of rpL3 gene expression via alternative pre-mRNA splicing. PMID: 21705779
    7. working model in which rpL3 recruits hnRNP H1 and, through cooperation with other splicing factors, promotes selection of the alternative splice site PMID: 20100605

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus, nucleolus. Cytoplasm.
  • 蛋白家族:
    Universal ribosomal protein uL3 family
  • 數據庫鏈接:

    HGNC: 10332

    OMIM: 604163

    KEGG: hsa:6122

    STRING: 9606.ENSP00000346001

    UniGene: Hs.119598



主站蜘蛛池模板: 国产精品久久久久久久久岛| 欧美成人午夜精品久久久| 伊人色综合久久天天五月婷| 欧美孕妇变态孕交粗暴| 亚欧欧美人成视频在线| 国产精品一区二区手机在线观看| 亚洲跨种族黑人xxxxx| 亚洲国产精品热久久| 成人性做爰aaa片免费看| 精品国产国语对白久久免费| 亚洲欧美成人一区二区在线| 草的我好爽视频| 福利姬液液酱喷水| 在线高清理伦片a| 精品免费国偷自产在线视频| 欧美黑人大战白嫩在线| 国产精品186在线观看在线播放| 午夜精品电影你懂的| 美女黄网站18禁免费看| 国产成人无码av一区二区在线观看| 97se亚洲国产综合自在线观看| 日本熟妇色一本在线观看| 图片区小说区另类春色| 6699嫩草久久久精品影院| 无码人妻一区二区三区免费| 2021最新精品国自产拍视频| 久久综合给合久久97色| 欧美人妻一区二区三区| 国产 精品 自在 线免费| 免费无码又爽又刺激成人| 男女高潮激烈免费观看| 爽爽精品dvd蜜桃成熟时电影院| 国产在热线精品视频99公交| 亚洲伊人久久成人综合网| 亚 洲 视 频 高 清 无 码| 国产精品成人久久电影| 国语对白做受xxxxx在| 亚洲伊人成综合网| 老司机亚洲精品影院无码| 成在人线av无码免费高潮喷水| 三级做爰高清视频|