在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ZFP57 Antibody

ZFP57 Antibody

  • 中文名稱：
    ZFP57兔多克隆抗體
  • 貨號：
    CSB-PA865138LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate, 293 whole cell lysate, Mouse brain tissue
      All lanes: ZFP57 antibody at 13.6µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 52, 60, 62 kDa
      Observed band size: 52 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ZFP57 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZFP57
  • 別名：
    ZFP57 antibody; C6orf40 antibody; ZNF698 antibody; Zinc finger protein 57 homolog antibody; Zfp-57 antibody; Zinc finger protein 698 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Zinc finger protein 57 homolog protein (183-295AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，ZFP57 Antibody (CSB-PA865138LA01HU)，的標(biāo)記方式是Non-conjugated。對于ZFP57 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA865138LB01HU ZFP57 Antibody, HRP conjugated ELISA
    FITC CSB-PA865138LC01HU ZFP57 Antibody, FITC conjugated
    Biotin CSB-PA865138LD01HU ZFP57 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs). Acts together with ZNF445, but ZNF445 seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element.
  • 基因功能參考文獻(xiàn)：
    1. transient neonatal diabetes type 1 is associated with ZFP57 mutations PMID: 27075368
    2. ZFP57 regulates the expression of insulin-like growth factor 2 (IGF2), which has a critical role in ZFP57-induced anchorage-independent growth PMID: 24469060
    3. High grade glioblastoma is associated with increased level of ZFP57, a protein involved in gene imprinting, and aberrant expression of CPT1A and CPT1C. PMID: 24618825
    4. These data identify ZFP57 as a candidate gene underlying reported MHC disease associations, notably for putative regulatory variants associated with cancer and HIV-1. PMID: 24193346
    5. Mouse and human ZFP57 are orthologs despite relatively low sequence identity. PMID: 24135613
    6. ZFP57 vZFP57 vZFP57 PMID: 23748067
    7. hZFP57 mutations and hypomethylation of the TNDM1 imprinted control region both associated with Transient Neonatal Diabetes Mellitus type 1 result in loss of hZFP57 binding to the TNDM1 locus. PMID: 23499433
    8. no evidence for ZFP57 alterations as a major cause in sporadic Beckwith-Wiedemann Syndrome cases PMID: 21863059
    9. this study does not provide evidence that ZFP57 mutations are the cause of 11p15-hypomethylation in Silver-Russell syndrome (SRS) patients and contribute to the aetiology of SRS PMID: 19632365
    10. Study reports mutations in ZFP57, which encodes a zinc-finger transcription factor expressed in early development, in seven pedigrees with a shared pattern of mosaic hypomethylation and a conserved range of clinical features. PMID: 18622393
    11. Observational study of gene-disease association. (HuGE Navigator) PMID: 19851445

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Transient neonatal diabetes mellitus 1 (TNDM1)
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family, ZFP57 subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18791

    OMIM: 601410

    KEGG: hsa:346171

    UniGene: Hs.156326



主站蜘蛛池模板： 无码h黄动漫在线播放网站| 天天做天天摸天天爽天天爱| 国产精品人妻| 亚洲精品福利一区二区三区蜜桃| 欧洲精品va无码一区二区三区| 浓毛欧美老妇乱子伦视频| 深夜福利在线观看视频| 日韩伦人妻无码| 疯狂迎合进入强壮公的视频| 手机国产乱子伦精品视频| 一本一道波多野结衣av一区| 久久人妻无码中文字幕第一| 亚洲国产精品va在线观看麻豆 | 韩产日产国产欧产| 精品亚洲欧美自拍| 人澡人人澡人人澡欧美| 无码aⅴ精品一区二区三区| 亚洲s码欧洲m码国产av| 欧美人禽杂交狂配免费看| √天堂中文最新版在线中文| 國产一二三内射在线看片| 亚洲熟妇中文字幕日产无码| 亚洲日韩中文字幕久热| 亚洲女人被黑人巨大进入| 亚洲精品国产精品乱码视色| 成人一区二区免费中文字幕视频| 亚洲成_人网站图片| 大桥久未无码吹潮在线观看| 国产成人精品.视频| 女人摸下面自熨视频在线播放 | 麻豆一区二区三区蜜桃免费| 亚洲人成精品久久久久桥| 在线精品亚洲一区二区小说| 性欧美丰满熟妇xxxx性仙踪林 | 国产成人精品福利一区二区三区| 国精产品蘑菇一区一区有限| 99久久99久久精品国产片果冻| 亚洲成a人片在线观看无码下载| 欧美日韩精品成人网站二区| 免费看欧美成人a片无码| 国产三区在线成人av|