在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ZFP57 Antibody, Biotin conjugated

ZFP57 Antibody, Biotin conjugated

  • 中文名稱：
    ZFP57兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA865138LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ZFP57 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZFP57
  • 別名：
    ZFP57 antibody; C6orf40 antibody; ZNF698 antibody; Zinc finger protein 57 homolog antibody; Zfp-57 antibody; Zinc finger protein 698 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein 57 homolog protein (183-295AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs). Acts together with ZNF445, but ZNF445 seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element.
  • 基因功能參考文獻(xiàn)：
    1. transient neonatal diabetes type 1 is associated with ZFP57 mutations PMID: 27075368
    2. ZFP57 regulates the expression of insulin-like growth factor 2 (IGF2), which has a critical role in ZFP57-induced anchorage-independent growth PMID: 24469060
    3. High grade glioblastoma is associated with increased level of ZFP57, a protein involved in gene imprinting, and aberrant expression of CPT1A and CPT1C. PMID: 24618825
    4. These data identify ZFP57 as a candidate gene underlying reported MHC disease associations, notably for putative regulatory variants associated with cancer and HIV-1. PMID: 24193346
    5. Mouse and human ZFP57 are orthologs despite relatively low sequence identity. PMID: 24135613
    6. ZFP57 vZFP57 vZFP57 PMID: 23748067
    7. hZFP57 mutations and hypomethylation of the TNDM1 imprinted control region both associated with Transient Neonatal Diabetes Mellitus type 1 result in loss of hZFP57 binding to the TNDM1 locus. PMID: 23499433
    8. no evidence for ZFP57 alterations as a major cause in sporadic Beckwith-Wiedemann Syndrome cases PMID: 21863059
    9. this study does not provide evidence that ZFP57 mutations are the cause of 11p15-hypomethylation in Silver-Russell syndrome (SRS) patients and contribute to the aetiology of SRS PMID: 19632365
    10. Study reports mutations in ZFP57, which encodes a zinc-finger transcription factor expressed in early development, in seven pedigrees with a shared pattern of mosaic hypomethylation and a conserved range of clinical features. PMID: 18622393
    11. Observational study of gene-disease association. (HuGE Navigator) PMID: 19851445

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Transient neonatal diabetes mellitus 1 (TNDM1)
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family, ZFP57 subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 18791

    OMIM: 601410

    KEGG: hsa:346171

    UniGene: Hs.156326



主站蜘蛛池模板： 性高湖久久久久久久久| 亚洲色偷偷偷网站色偷一区 | 在线 v亚洲 v欧美v 专区| 无码视频一区二区三区在线观看| 少妇真实被内射视频三四区| 男女同房做爰爽免费| 日本19禁啪啪吃奶大尺度| 永久免费观看国产裸体美女| 最新亚洲春色av无码专区| 国产精品一区二区香蕉| h人成在线看免费视频| 亚洲人成色77777| 国产精品无码久久久久成人影院 | 午夜裸体性播放| 久久/这里只精品99re66| 国产精品高潮呻吟av久久黄| 国产一区二区三区不卡av| 小sao货水好多真紧h无码视频| 黑人巨大无码中文字幕无码| 麻豆视传媒官网免费观看| 92国产精品午夜福利免费| 国产伦精品一区二区三区| 国产制服丝袜亚洲高清| 小12箩利洗澡无码视频网站| 国产又粗又猛又黄又爽无遮挡 | 精品久久久久中文字幕加勒比| 日本三级欧美三级人妇视频| 无码一区二区三区在线| 亚洲中文字幕无码一久久区| 偷窥 亚洲 另类 图片 熟女| 日韩人妻无码免费视频一区二区| 日本无码欧美一区精品久久| 特级a做爰全过程片| 欧美大片欧美激情性色a∨在线| 无码成a毛片免费| 国产成人人人97超碰超爽8| 亚洲人成77777在线播放网站| 精品免费国产一区二区三区四区介绍 | 国产v综合v亚洲欧美久久| 国内精品乱码卡一卡2卡三卡新区| 欧洲精品卡一卡二卡三|