在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. USP20 Antibody, HRP conjugated

USP20 Antibody, HRP conjugated

  • 中文名稱：
    USP20兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA896876LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) USP20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    USP20
  • 別名：
    Deubiquitinating enzyme 20 antibody; hVDU2 antibody; KIAA1003 antibody; LSFR 3A antibody; LSFR3A antibody; pVHL interacting deubiquitinating enzyme 2 antibody; Ubiquitin carboxyl terminal hydrolase 20 antibody; Ubiquitin carboxyl-terminal hydrolase 20 antibody; ubiquitin specific peptidase 20 antibody; Ubiquitin specific processing protease 20 antibody; Ubiquitin specific protease 20 antibody; Ubiquitin thioesterase 20 antibody; Ubiquitin thiolesterase 20 antibody; Ubiquitin-specific-processing protease 20 antibody; UBP20_HUMAN antibody; USP 20 antibody; USP20 antibody; VDU 2 antibody; VDU2 antibody; VHL interacting deubiquitinating enzyme 2 antibody; VHL-interacting deubiquitinating enzyme 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 20 protein (258-417AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • 基因功能參考文獻：
    1. USP20 regulates actin cytoskeleton organization and cell migration in a manner dependent on ERK3 expression. The results identify USP20 as a bona fide regulator of ERK3 stability and physiological functions. PMID: 28167606
    2. we investigated the inter-action between PKM2 and USP20. Our results suggest a new molecular pathway in cancer metabolism through the regulation of PKM2. PMID: 25708858
    3. findings reveal a dynamic regulation of USP20 by site-specific phosphorylation as well as the interdependence of signal transduction and trafficking pathways in balancing adrenergic stimulation and maintaining cellular homeostasis PMID: 25666616
    4. data establish a new function of USP20 in genome maintenance and DNA repair. PMID: 24923443
    5. Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population. PMID: 22552337
    6. Our results point to USP20 as a key negative regulator of HTLV-1 Tax-induced NF-kappaB signaling. PMID: 21525354
    7. identification and description of VDU2 in human cells PMID: 12865408
    8. von Hippel-Lindau protein-interacting deubiquitinating enzyme 2 (VDU2) deubiquitinates and stabilizes HIF-1alpha. PMID: 15776016
    9. USPs 20 and 33 serve as novel regulators that dictate both post-endocytic sorting as well as the intensity and extent of beta(2)AR signalling from the cell surface. PMID: 19424180

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=According to PubMed:12865408, it localizes in the endoplasmic reticulum; however the relevance of such result is unclear.
  • 蛋白家族：
    Peptidase C19 family, USP20/USP33 subfamily
  • 數據庫鏈接：

    HGNC: 12619

    OMIM: 615143

    KEGG: hsa:10868

    STRING: 9606.ENSP00000313811

    UniGene: Hs.5452



主站蜘蛛池模板： 国产成人av免费观看| 少妇一晚三次一区二区三区| 日日碰狠狠躁久久躁婷婷| 牛和人交xxxx欧美| 亚洲欧美日韩中文加勒比| 欧美牲交视频免费观看| 熟妇的奶头又大又粗视频| 欧美丰满熟妇xxxx性大屁股| 亚洲精品一区二区三区在线观看| 欧美人禽杂交狂配免费看| 亚洲色无码播放| 色老板精品视频在线观看| 国产产无码乱码精品久久鸭| 色视频无码专区在线观看| 国产无遮挡a片无码免费软件| 亚洲午夜国产精品无码老牛影视| 狂野av人人澡人人添| 精品国产av一区二区果冻传媒 | 日本一道高清一区二区三区| 上司人妻互换中文字幕| 久久久久久毛片免费播放| 狠狠久久久久综合成人影院| 久久99精品网久久| 天堂а√在线最新版中文在线| 国产熟妇高潮呻吟喷水| av综合网男人的天堂| 华人少妇被黑人粗大的猛烈进| 久久久精品人妻久久影视| 曰本大码熟中文字幕| 久久久国产精品麻豆a片| 欧美老熟妇videos极品另类| 亚洲熟女乱综合一区二区在线| 99久久国产成人免费网站| 午夜天堂一区人妻| 蜜臀av一区二区| 久久人人97超碰超国产| 国产情侣一区二区| 国产成a人亚洲精品无码樱花| 新普新京亚洲欧美日韩国产| 国产精品久久久久影院亚瑟| 国产精品9999久久久久仙踪林 |