在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. USP20 Antibody, FITC conjugated

USP20 Antibody, FITC conjugated

  • 中文名稱：
    USP20兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA896876LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) USP20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    USP20
  • 別名：
    Deubiquitinating enzyme 20 antibody; hVDU2 antibody; KIAA1003 antibody; LSFR 3A antibody; LSFR3A antibody; pVHL interacting deubiquitinating enzyme 2 antibody; Ubiquitin carboxyl terminal hydrolase 20 antibody; Ubiquitin carboxyl-terminal hydrolase 20 antibody; ubiquitin specific peptidase 20 antibody; Ubiquitin specific processing protease 20 antibody; Ubiquitin specific protease 20 antibody; Ubiquitin thioesterase 20 antibody; Ubiquitin thiolesterase 20 antibody; Ubiquitin-specific-processing protease 20 antibody; UBP20_HUMAN antibody; USP 20 antibody; USP20 antibody; VDU 2 antibody; VDU2 antibody; VHL interacting deubiquitinating enzyme 2 antibody; VHL-interacting deubiquitinating enzyme 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 20 protein (258-417AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • 基因功能參考文獻：
    1. USP20 regulates actin cytoskeleton organization and cell migration in a manner dependent on ERK3 expression. The results identify USP20 as a bona fide regulator of ERK3 stability and physiological functions. PMID: 28167606
    2. we investigated the inter-action between PKM2 and USP20. Our results suggest a new molecular pathway in cancer metabolism through the regulation of PKM2. PMID: 25708858
    3. findings reveal a dynamic regulation of USP20 by site-specific phosphorylation as well as the interdependence of signal transduction and trafficking pathways in balancing adrenergic stimulation and maintaining cellular homeostasis PMID: 25666616
    4. data establish a new function of USP20 in genome maintenance and DNA repair. PMID: 24923443
    5. Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population. PMID: 22552337
    6. Our results point to USP20 as a key negative regulator of HTLV-1 Tax-induced NF-kappaB signaling. PMID: 21525354
    7. identification and description of VDU2 in human cells PMID: 12865408
    8. von Hippel-Lindau protein-interacting deubiquitinating enzyme 2 (VDU2) deubiquitinates and stabilizes HIF-1alpha. PMID: 15776016
    9. USPs 20 and 33 serve as novel regulators that dictate both post-endocytic sorting as well as the intensity and extent of beta(2)AR signalling from the cell surface. PMID: 19424180

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=According to PubMed:12865408, it localizes in the endoplasmic reticulum; however the relevance of such result is unclear.
  • 蛋白家族：
    Peptidase C19 family, USP20/USP33 subfamily
  • 數據庫鏈接：

    HGNC: 12619

    OMIM: 615143

    KEGG: hsa:10868

    STRING: 9606.ENSP00000313811

    UniGene: Hs.5452



主站蜘蛛池模板： 大帝a∨无码视频在线播放| 亚洲熟妇久久国内精品| 中文字幕漂亮人妻熟睡中被公侵犯 | 在线视频国产制服丝袜| 又色又爽又黄又无遮挡的网站 | 男女裸体下面进入的免费视频 | 久久精品中文字幕第一页| 无码人妻丰满熟妇奶水区码| 天天躁夜夜躁狠狠眼泪| 男女车车的车车网站w98免费| 国产亚洲精品电影网站在线观看| 日本熟妇乱子伦xxxx| 中国亚洲女人69内射少妇| 日韩在线一区二区三区免费视频| 亚洲中文字幕伊人久久无码| 婷婷网色偷偷亚洲男人甘肃| 久久精品国产69国产精品亚洲| 狠狠色噜噜狠狠狠888米奇视频| 97久久超碰国产精品最新| 人妻系列无码一区二区三区| 三上悠亚久久精品| 久久久亚洲欧洲日产国码农村| 国产成人精品久久久久精品日日| 蜜臀av 国内精品久久久| 国产无套精品一区二区三区| 久久亚洲精品成人av无码网站| 国产亚洲精品合集久久久久| 无码国产一区二区免费| 国产情侣久久久久aⅴ免费| 小宝贝荡货啊用力水湿aⅴ视频| 久久狼人大香伊蕉国产| 国产一区日韩二区欧美三区| 欧美艳星nikki激情办公室| 欧美嫩交一区二区三区| 亚洲乱码日产精品bd在观看| 日韩网红少妇无码视频香港 | 开心久久婷婷综合中文字幕| 99久久精品精品6精品精品| 中文字幕aav| 日韩欧美亚洲综合久久影院| 久久电影网午夜鲁丝片免费|