在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. USP20 Antibody, Biotin conjugated

USP20 Antibody, Biotin conjugated

  • 中文名稱：
    USP20兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA896876LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) USP20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    USP20
  • 別名：
    Deubiquitinating enzyme 20 antibody; hVDU2 antibody; KIAA1003 antibody; LSFR 3A antibody; LSFR3A antibody; pVHL interacting deubiquitinating enzyme 2 antibody; Ubiquitin carboxyl terminal hydrolase 20 antibody; Ubiquitin carboxyl-terminal hydrolase 20 antibody; ubiquitin specific peptidase 20 antibody; Ubiquitin specific processing protease 20 antibody; Ubiquitin specific protease 20 antibody; Ubiquitin thioesterase 20 antibody; Ubiquitin thiolesterase 20 antibody; Ubiquitin-specific-processing protease 20 antibody; UBP20_HUMAN antibody; USP 20 antibody; USP20 antibody; VDU 2 antibody; VDU2 antibody; VHL interacting deubiquitinating enzyme 2 antibody; VHL-interacting deubiquitinating enzyme 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 20 protein (258-417AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • 基因功能參考文獻(xiàn)：
    1. USP20 regulates actin cytoskeleton organization and cell migration in a manner dependent on ERK3 expression. The results identify USP20 as a bona fide regulator of ERK3 stability and physiological functions. PMID: 28167606
    2. we investigated the inter-action between PKM2 and USP20. Our results suggest a new molecular pathway in cancer metabolism through the regulation of PKM2. PMID: 25708858
    3. findings reveal a dynamic regulation of USP20 by site-specific phosphorylation as well as the interdependence of signal transduction and trafficking pathways in balancing adrenergic stimulation and maintaining cellular homeostasis PMID: 25666616
    4. data establish a new function of USP20 in genome maintenance and DNA repair. PMID: 24923443
    5. Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population. PMID: 22552337
    6. Our results point to USP20 as a key negative regulator of HTLV-1 Tax-induced NF-kappaB signaling. PMID: 21525354
    7. identification and description of VDU2 in human cells PMID: 12865408
    8. von Hippel-Lindau protein-interacting deubiquitinating enzyme 2 (VDU2) deubiquitinates and stabilizes HIF-1alpha. PMID: 15776016
    9. USPs 20 and 33 serve as novel regulators that dictate both post-endocytic sorting as well as the intensity and extent of beta(2)AR signalling from the cell surface. PMID: 19424180

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=According to PubMed:12865408, it localizes in the endoplasmic reticulum; however the relevance of such result is unclear.
  • 蛋白家族：
    Peptidase C19 family, USP20/USP33 subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 12619

    OMIM: 615143

    KEGG: hsa:10868

    STRING: 9606.ENSP00000313811

    UniGene: Hs.5452



主站蜘蛛池模板： 无码人妻精品一区二区三区9厂| 国产在线乱子伦一区二区| 国产色无码精品视频免费| 美女裸体视频永久免费| 亚洲欧洲无卡二区视頻| 国产成人免费永久播放视频平台 | 久久久欧美精品激情| 久久九九精品国产免费看小说 | 久久久精品日本一区二区三区| 国产亚洲精品久久久久久| 啊轻点内射在线视频| 五月激情婷婷丁香综合基地| 精品欧美一区二区三区久久久| 给我免费的视频在线观看| 国产精品成人无码久久久| 美女人妻激情乱人伦| 久久综合av色老头免费观看| 少妇人妻丰满做爰xxx| 久久伊人色av天堂九九| 国产精品午夜福利不卡120| 欧洲美熟女乱又伦av| 无码h肉动漫在线观看| 法国啄木乌av片在线播放| 女人与牲口性恔配视频免费| 久久99精品久久久久久不卡| 中出人妻中文字幕无码| 99在线精品一区二区三区| 亚洲一区精品无码色成人| 无码人妻精品一区二区蜜桃色欲 | 狠狠噜天天噜日日噜| 国产丰满老熟女重口对白| 日本亚洲国产一区二区三区| 亚洲成av人片在线观看无| 99精品人妻无码专区在线视频区| 无码写真精品永久福利在线| 9lporm自拍视频区| 欧美日韩色另类综合| 国产成人无码av在线影院| 夜夜躁狠狠躁日日躁2022| 欧美乱妇日本无乱码特黄大片 | 夜夜躁很很躁日日躁麻豆|