在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UHMK1 Antibody

  • 中文名稱:
    UHMK1兔多克隆抗體
  • 貨號:
    CSB-PA840554LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: Mouse brain tissue
      All lanes: UHMK1 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 47, 39, 40 kDa
      Observed band size: 47 kDa
    • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA840554LA01HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA840554LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) UHMK1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    UHMK1
  • 別名:
    DKFZp434C1613 antibody; FLJ23015 antibody; kinase interacting with leukemia-associated gene (stathmin) antibody; Kinase interacting with stathmin antibody; KIS antibody; KIS protein kinase antibody; KIST antibody; OTTHUMP00000029529 antibody; P-CIP2 antibody; Serine threonine protein kinase Kist antibody; Serine/threonine-protein kinase Kist antibody; U2AF homology motif (UHM) kinase 1 antibody; U2AF homology motif kinase 1 antibody; UHMK1 antibody; UHMK1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Serine/threonine-protein kinase Kist protein (183-385AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,UHMK1 Antibody (CSB-PA840554LA01HU),的標記方式是Non-conjugated。對于UHMK1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA840554LB01HU UHMK1 Antibody, HRP conjugated ELISA
    FITC CSB-PA840554LC01HU UHMK1 Antibody, FITC conjugated
    Biotin CSB-PA840554LD01HU UHMK1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA.
  • 基因功能參考文獻:
    1. UHMK1 plays a role in hematopoietic cell differentiation and suppression of autonomous clonal growth of leukemia cells. PMID: 29307747
    2. genome-wide association study identified the UHMK1 gene as a novel bone mineral density locus specific to East Asians. PMID: 27424934
    3. The contribution of UHMK1 gene in schizophrenia susceptibility, was explored. PMID: 21399567
    4. We identify the kinase responsible for S10 phosphorylation as human kinase interacting stathmin (hKIS) and show that it regulates cell cycle progression in response to mitogens. PMID: 12093740
    5. KIS gene was overexpressed in NF1-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1-associated tumors. PMID: 12782393
    6. These results provide preliminary evidence that the UHMK1 gene increases susceptibility to schizophrenia. Further confirmation in adequately powered samples is needed. PMID: 16978587
    7. KIS promoter is activated by serum-responsive GABP binding to Ets-binding sites which leads to KIS gene expression, cell migration, and cell cycle progression PMID: 17726090
    8. Results show that KIS is a direct transcriptional target of FoxM1. PMID: 17984092
    9. Overexpression of KIS protein kinase is associated with acute myelogenous leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia PMID: 18384876
    10. The association between UHMK1 and schizophrenia is confirmed. PMID: 18414510
    11. KIS is expressed in neurons, and its encoded protein is localised to the nucleus and cytoplasm. No difference in KIS expression was found between schizophrenics and controls or in the lymphoblast cell lines. PMID: 19747464
    12. A follow up article showing further association between markers in UHMK1 and schizophrenia in a London based sample. Association replicated in an independent Scottish sample. PMID: 18414510
    13. Evidence indicating that UHMK1 may be a candidate susceptibility gene for Schizophrenia in the British population. UHMK1 is situated between previously implicated genes RGS4 and NOS1AP. PMID: 16978587

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性:
    Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 19683

    OMIM: 608849

    KEGG: hsa:127933

    STRING: 9606.ENSP00000420270

    UniGene: Hs.127310



主站蜘蛛池模板: 精品国产va久久久久久久冰| 国产福利日本一区二区三区| 色情无码www视频无码区澳门| 精产国品一二三产区蘑菇视频| 色欲天天婬色婬香综合网完整版 | 日韩免费无码人妻波多野| 2020精品国产a不卡片| 国产女人好紧好爽| 韩国三级在线观看久| 亚洲精品国产自在现线看| 亚洲精品色情app在线下载观看| 国模杨依粉嫩蝴蝶150p| 精品久久久久久久久久中文字幕 | 亚洲精品无码不卡av| 精品无人国产偷自产在线| 亚洲日韩一页精品发布| 六月丁香综合在线视频| 亚洲熟妇av日韩熟妇av| 欧美又粗又大xxxxbbbb疯狂| 97视频在线观看播放| 欧美性狂猛xxxxx深喉| 亚洲色欲色欲www在线看| 亚洲乱码国产乱码精品精| 少妇午夜啪爽嗷嗷叫视频| 人妻天天爽夜夜爽精品视频| 久久亚洲精品人成综合网| 国产精品videossex国产高清| 日韩欧美亚洲综合久久| 99re6热视频这里只精品首页 | 99久re热视频这里只有精品6| 精品国产一区二区三区久久| 精品国产乱码久久久久久免费| 男女免费观看做爰视频在线观看| 国产经典三级av在线播放| 国产成人a人亚洲精v品无码| 免费人成视频x8x8入口| 国产aⅴ爽av久久久久久| 成人免费无码大片a毛片小说| 亚洲人亚洲精品成人网站| 国产在线一卡2卡三卡4卡免费| 男女久久久国产一区二区三区|