在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UHMK1 Antibody, Biotin conjugated

  • 中文名稱:
    UHMK1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA840554LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) UHMK1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    UHMK1
  • 別名:
    DKFZp434C1613 antibody; FLJ23015 antibody; kinase interacting with leukemia-associated gene (stathmin) antibody; Kinase interacting with stathmin antibody; KIS antibody; KIS protein kinase antibody; KIST antibody; OTTHUMP00000029529 antibody; P-CIP2 antibody; Serine threonine protein kinase Kist antibody; Serine/threonine-protein kinase Kist antibody; U2AF homology motif (UHM) kinase 1 antibody; U2AF homology motif kinase 1 antibody; UHMK1 antibody; UHMK1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Serine/threonine-protein kinase Kist protein (183-385AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA.
  • 基因功能參考文獻:
    1. UHMK1 plays a role in hematopoietic cell differentiation and suppression of autonomous clonal growth of leukemia cells. PMID: 29307747
    2. genome-wide association study identified the UHMK1 gene as a novel bone mineral density locus specific to East Asians. PMID: 27424934
    3. The contribution of UHMK1 gene in schizophrenia susceptibility, was explored. PMID: 21399567
    4. We identify the kinase responsible for S10 phosphorylation as human kinase interacting stathmin (hKIS) and show that it regulates cell cycle progression in response to mitogens. PMID: 12093740
    5. KIS gene was overexpressed in NF1-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1-associated tumors. PMID: 12782393
    6. These results provide preliminary evidence that the UHMK1 gene increases susceptibility to schizophrenia. Further confirmation in adequately powered samples is needed. PMID: 16978587
    7. KIS promoter is activated by serum-responsive GABP binding to Ets-binding sites which leads to KIS gene expression, cell migration, and cell cycle progression PMID: 17726090
    8. Results show that KIS is a direct transcriptional target of FoxM1. PMID: 17984092
    9. Overexpression of KIS protein kinase is associated with acute myelogenous leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia PMID: 18384876
    10. The association between UHMK1 and schizophrenia is confirmed. PMID: 18414510
    11. KIS is expressed in neurons, and its encoded protein is localised to the nucleus and cytoplasm. No difference in KIS expression was found between schizophrenics and controls or in the lymphoblast cell lines. PMID: 19747464
    12. A follow up article showing further association between markers in UHMK1 and schizophrenia in a London based sample. Association replicated in an independent Scottish sample. PMID: 18414510
    13. Evidence indicating that UHMK1 may be a candidate susceptibility gene for Schizophrenia in the British population. UHMK1 is situated between previously implicated genes RGS4 and NOS1AP. PMID: 16978587

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性:
    Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 19683

    OMIM: 608849

    KEGG: hsa:127933

    STRING: 9606.ENSP00000420270

    UniGene: Hs.127310



主站蜘蛛池模板: 男人扒开添女人下部免费视频| 中文字幕精品一二三四五六七八| 亚洲夂夂婷婷色拍ww47 | 国产免国产免费| 2020最新国产在线不卡a| 国产精品人成电影在线观看| 伊人久久大香线蕉综合75| 亚洲日本一区二区一本一道| 一线二线无人区乱码 | 久久久久77777人人人人人| 2019精品国自产拍在线不卡| 国产精品无码天天爽视频| 亚洲国产精品综合久久网络| 中出あ人妻熟女中文字幕| 人妻性奴波多野结衣无码| 97高清国语自产拍| 中文字幕在线观看亚洲日韩| 久青草影院在线观看国产| 又大又粗又长的高潮视频| 人妻巨大乳一二三区| 天天做天天爱天天综合网2021 | 欧美日韩精品成人网站二区| 国产成人亚洲综合无码| 大伊香蕉精品视频在线天堂| 少妇与子乱在线观看| 久久精品国产2020| 美女无遮挡免费视频网站| 亚洲偷自拍国综合| 日本熟妇美熟bbw| 亚洲女人被黑人巨大进入| 精品人妻无码专区中文字幕| 亚 洲 成 人 网站在线观看| 亚洲精品国产av成拍色拍婷婷| 好爽…又高潮了毛片免费看| 国产亚洲视频在线观看播放 | 色欲色香天天天综合无码| 亚洲欧美成αⅴ人在线观看| 成人久久久久久久久久久| 欧美日韩精品一区二区视频| 亚洲乱码日产精品bd| 夜夜躁天天躁很很躁|