在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UHMK1 Antibody, HRP conjugated

  • 中文名稱:
    UHMK1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA840554LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) UHMK1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    UHMK1
  • 別名:
    DKFZp434C1613 antibody; FLJ23015 antibody; kinase interacting with leukemia-associated gene (stathmin) antibody; Kinase interacting with stathmin antibody; KIS antibody; KIS protein kinase antibody; KIST antibody; OTTHUMP00000029529 antibody; P-CIP2 antibody; Serine threonine protein kinase Kist antibody; Serine/threonine-protein kinase Kist antibody; U2AF homology motif (UHM) kinase 1 antibody; U2AF homology motif kinase 1 antibody; UHMK1 antibody; UHMK1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Serine/threonine-protein kinase Kist protein (183-385AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA.
  • 基因功能參考文獻:
    1. UHMK1 plays a role in hematopoietic cell differentiation and suppression of autonomous clonal growth of leukemia cells. PMID: 29307747
    2. genome-wide association study identified the UHMK1 gene as a novel bone mineral density locus specific to East Asians. PMID: 27424934
    3. The contribution of UHMK1 gene in schizophrenia susceptibility, was explored. PMID: 21399567
    4. We identify the kinase responsible for S10 phosphorylation as human kinase interacting stathmin (hKIS) and show that it regulates cell cycle progression in response to mitogens. PMID: 12093740
    5. KIS gene was overexpressed in NF1-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1-associated tumors. PMID: 12782393
    6. These results provide preliminary evidence that the UHMK1 gene increases susceptibility to schizophrenia. Further confirmation in adequately powered samples is needed. PMID: 16978587
    7. KIS promoter is activated by serum-responsive GABP binding to Ets-binding sites which leads to KIS gene expression, cell migration, and cell cycle progression PMID: 17726090
    8. Results show that KIS is a direct transcriptional target of FoxM1. PMID: 17984092
    9. Overexpression of KIS protein kinase is associated with acute myelogenous leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia PMID: 18384876
    10. The association between UHMK1 and schizophrenia is confirmed. PMID: 18414510
    11. KIS is expressed in neurons, and its encoded protein is localised to the nucleus and cytoplasm. No difference in KIS expression was found between schizophrenics and controls or in the lymphoblast cell lines. PMID: 19747464
    12. A follow up article showing further association between markers in UHMK1 and schizophrenia in a London based sample. Association replicated in an independent Scottish sample. PMID: 18414510
    13. Evidence indicating that UHMK1 may be a candidate susceptibility gene for Schizophrenia in the British population. UHMK1 is situated between previously implicated genes RGS4 and NOS1AP. PMID: 16978587

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性:
    Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 19683

    OMIM: 608849

    KEGG: hsa:127933

    STRING: 9606.ENSP00000420270

    UniGene: Hs.127310



主站蜘蛛池模板: 人妻少妇精品视频一区二区三区 | 国产精品夜夜春夜夜爽久久小说| 美女视频黄频大全免费| 国产精品毛片va一区二区三区| 国产又色又爽又黄的在线观看视频| 波多老师无码av中字专区| av天堂午夜精品蜜臀av| 秋霞特色aa大片| 曰韩少妇内射免费播放| 日韩美女自卫慰黄网站| 2021国产成人精品久久| 性生交大片免费看女人按摩 | 国产精品激情欧美可乐视频| 亚洲最大无码av网站观看 | 无套内谢孕妇毛片免费看| 东北少妇不戴套对白第一次| 国产成人无码午夜福利在线直播| 和黑人邻居中文字幕在线| 无码人妻久久久一区二区三区| 人妻无码中文字幕| 亚洲精品国产自在久久| 男女下面一进一出无遮挡| 中文字幕无线码一区2020青青| 免费看成人aa片无码视频| 天堂√在线中文最新版| 日本猛少妇色xxxxx猛叫| 好爽…又高潮了免费毛片| 一本久久伊人热热精品中文字幕| 漂亮人妻被强中文字幕久久| 亚洲国产精品久久精品| 天堂俺去俺来也www色官网| 亚洲精品久久一区二区无卡| 老色鬼在线精品视频| 国产男女无遮挡猛进猛出| 日本天天黄网站| 米奇7777狠狠狠狠视频影院| 风韵丰满熟妇啪啪区老老熟妇| 中文字幕卡二和卡三的视频| 亚洲午夜高清国产拍| 成人天堂婷婷青青视频在线观看| 亚洲精品国产精华液有哪些|