在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UHMK1 Antibody, HRP conjugated

  • 中文名稱:
    UHMK1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA840554LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) UHMK1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    UHMK1
  • 別名:
    DKFZp434C1613 antibody; FLJ23015 antibody; kinase interacting with leukemia-associated gene (stathmin) antibody; Kinase interacting with stathmin antibody; KIS antibody; KIS protein kinase antibody; KIST antibody; OTTHUMP00000029529 antibody; P-CIP2 antibody; Serine threonine protein kinase Kist antibody; Serine/threonine-protein kinase Kist antibody; U2AF homology motif (UHM) kinase 1 antibody; U2AF homology motif kinase 1 antibody; UHMK1 antibody; UHMK1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Serine/threonine-protein kinase Kist protein (183-385AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA.
  • 基因功能參考文獻:
    1. UHMK1 plays a role in hematopoietic cell differentiation and suppression of autonomous clonal growth of leukemia cells. PMID: 29307747
    2. genome-wide association study identified the UHMK1 gene as a novel bone mineral density locus specific to East Asians. PMID: 27424934
    3. The contribution of UHMK1 gene in schizophrenia susceptibility, was explored. PMID: 21399567
    4. We identify the kinase responsible for S10 phosphorylation as human kinase interacting stathmin (hKIS) and show that it regulates cell cycle progression in response to mitogens. PMID: 12093740
    5. KIS gene was overexpressed in NF1-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1-associated tumors. PMID: 12782393
    6. These results provide preliminary evidence that the UHMK1 gene increases susceptibility to schizophrenia. Further confirmation in adequately powered samples is needed. PMID: 16978587
    7. KIS promoter is activated by serum-responsive GABP binding to Ets-binding sites which leads to KIS gene expression, cell migration, and cell cycle progression PMID: 17726090
    8. Results show that KIS is a direct transcriptional target of FoxM1. PMID: 17984092
    9. Overexpression of KIS protein kinase is associated with acute myelogenous leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia PMID: 18384876
    10. The association between UHMK1 and schizophrenia is confirmed. PMID: 18414510
    11. KIS is expressed in neurons, and its encoded protein is localised to the nucleus and cytoplasm. No difference in KIS expression was found between schizophrenics and controls or in the lymphoblast cell lines. PMID: 19747464
    12. A follow up article showing further association between markers in UHMK1 and schizophrenia in a London based sample. Association replicated in an independent Scottish sample. PMID: 18414510
    13. Evidence indicating that UHMK1 may be a candidate susceptibility gene for Schizophrenia in the British population. UHMK1 is situated between previously implicated genes RGS4 and NOS1AP. PMID: 16978587

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性:
    Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 19683

    OMIM: 608849

    KEGG: hsa:127933

    STRING: 9606.ENSP00000420270

    UniGene: Hs.127310



主站蜘蛛池模板: 日本三级香港三级三级人!妇久 | 久久人人玩人妻潮喷内射人人| 97精品一区二区视频在线观看| 丝袜无码专区人妻视频| 日本成本人三级在线观看| 久久精品伊人一区二区三区| 亚洲a∨无码无在线观看| 色综合久久88色综合天天| 欧美 亚洲 国产 制服 中文 | 欧美日产亚洲国产精品| 无遮挡十八禁污污污网站| 无码一区二区三区亚洲人妻| 中文乱码人妻系列一区二区| 亚洲精品无码久久毛片波多野吉衣| 亚洲日韩欧美在线成人 | 国产亚洲精品美女在线| 人妻插b视频一区二区三区 | 国产96在线 | 欧美| 人妻人人澡人人添人人爽人人玩| 国产成人av在线免播放观看| 中国丰满人妻videoshd| 妺妺窝人体色www在线| 动漫精品无码h在线观看| 一区二区三区无码免费看| 乱妇乱女熟妇熟女网站| 亚洲无线看天堂av| 国产三级视频在线播放线观看| 亚洲女人被黑人巨大进入| 一本色道久久88综合日韩精品| 欧美日韩精品suv| 2020国产精品午夜福利在线观看| 国产毛片欧美毛片久久久| 天堂mv在线mv免费mv香蕉| 2019精品国自产拍在线不卡| 国产精品视频一区二区噜噜| 高清欧美性猛交xxxx黑人猛交| 久久爱www人成狠狠爱综合网| 永久免费看啪啪网址入口| 国产av无码专区国产乱码| 亚洲精品久久久久高潮| 蜜臀av999无码精品国产专区|