在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRIM17 Antibody, HRP conjugated

  • 中文名稱:
    TRIM17兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA897559LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TRIM17 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TRIM17
  • 別名:
    E3 ubiquitin-protein ligase TRIM17 antibody; RBCC antibody; RING finger protein 16 antibody; RING finger protein terf antibody; RNF16 antibody; TERF antibody; Testis RING finger protein antibody; TRI17_HUMAN antibody; TRIM 17 antibody; Trim17 antibody; Tripartite motif containing 17 antibody; Tripartite motif containing protein 17 antibody; Tripartite motif protein 17 antibody; Tripartite motif-containing protein 17 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human E3 ubiquitin-protein ligase TRIM17 protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    E3 ubiquitin ligase that plays important roles in the regulation of neuronal apoptosis, selective autophagy or cell proliferation. Stimulates the degradation of kinetochore ZW10 interacting protein ZWINT in a proteasome-dependent manner, leading to negative regulation of cell proliferation. Inhibits autophagic degradation of diverse known targets while contributing to autophagy of midbodies. Autophagy-inhibitory activity involves MCL1, which TRIM17 assembles into complexes with the key autophagy regulator BECN1. Controls neuronal apoptosis by mediating ubiquitination and degradation of MCL1 to initiate neuronal death. In addition, regulates NFAT transcription factors NFATC3 and NFATC4 activities by preventing their nuclear localization, thus inhibiting their transcriptional activities. Decreases TRIM41-mediated degradation of ZSCAN2 thereby stimulating alpha-synuclein/SNCA transcription in neuronal cells. Prevents the E3 ubiquitin-ligase activity of TRIM28 and its interaction with anti-apoptotic BCL2A1, blocking TRIM28 from ubiquitinating BCL2A1.
  • 基因功能參考文獻:
    1. TRIM17 promoted the removal of midbodies, remnants of the cell division machinery that are known autophagy targets. PMID: 27562068
    2. NFATc3 interacted in a SUMO-dependent manner with Trim17, an E3 ubiquitin ligase necessary for neuronal apoptosis PMID: 25215946
    3. terf interacts with TRIM44;TRIM44 inhibited ubiquitination of terf, and thus stabilized the protein. PMID: 19358823
  • 亞細胞定位:
    Cytoplasm. Lysosome.
  • 蛋白家族:
    TRIM/RBCC family
  • 組織特異性:
    Almost exclusively in the testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 13430

    OMIM: 606123

    KEGG: hsa:51127

    STRING: 9606.ENSP00000295033

    UniGene: Hs.121748



主站蜘蛛池模板: 国产婷婷色一区二区三区| 婷婷色婷婷开心五月四房播播久久 | 国产99视频精品免费视频76| 免费人成网站视频在线观看国内| 人妻无码av中文系列久| 性欧美欧美巨大69| 国产精品久久久久影院| 好男人资源在线www免费| 日本熟妇厨房bbw| 久久久久久久综合色一本| 国产真人无码作爱视频免费| 亚洲va在线va天堂xxxx| 成年美女黄网站18禁免费| 女被男啪到哭的视频网站 | 久久久久亚洲精品天堂| 国产交换配偶在线视频| 97精品国产一区二区三区| 狠狠色噜噜狠狠狠狠av不卡| 丰满少妇被粗大猛烈进人高清| 国产成人综合日韩精品无码不卡| 风间由美性色一区二区三区| 欧美熟妇的性裸交| 国产欧美另类久久久精品丝瓜| 中国丰满少妇人妻xxx性董鑫洁| 精品国精品无码自拍自在线| 女人爽到喷水的视频大全| 亚洲精品无码久久久久av麻豆| 国产成人亚洲综合| 337p日本欧洲亚洲大胆色噜噜| 国产亚洲日韩在线aaaa| 99re在线播放| 日本一卡二卡不卡视频查询| 激情综合亚洲色婷婷五月| 一边啪啪一边呻吟av夜夜嗨| 中文字幕人乱码中文字幕 | 国产精品无码专区第一页| 女人喷液抽搐高潮视频| 亚洲国产专区校园欧美| 久久精品国产清高在天天线| 免费99精品国产自在在线| 免费无码久久成人影片|