在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRIM17 Antibody, Biotin conjugated

  • 中文名稱:
    TRIM17兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA897559LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TRIM17 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TRIM17
  • 別名:
    E3 ubiquitin-protein ligase TRIM17 antibody; RBCC antibody; RING finger protein 16 antibody; RING finger protein terf antibody; RNF16 antibody; TERF antibody; Testis RING finger protein antibody; TRI17_HUMAN antibody; TRIM 17 antibody; Trim17 antibody; Tripartite motif containing 17 antibody; Tripartite motif containing protein 17 antibody; Tripartite motif protein 17 antibody; Tripartite motif-containing protein 17 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human E3 ubiquitin-protein ligase TRIM17 protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    E3 ubiquitin ligase that plays important roles in the regulation of neuronal apoptosis, selective autophagy or cell proliferation. Stimulates the degradation of kinetochore ZW10 interacting protein ZWINT in a proteasome-dependent manner, leading to negative regulation of cell proliferation. Inhibits autophagic degradation of diverse known targets while contributing to autophagy of midbodies. Autophagy-inhibitory activity involves MCL1, which TRIM17 assembles into complexes with the key autophagy regulator BECN1. Controls neuronal apoptosis by mediating ubiquitination and degradation of MCL1 to initiate neuronal death. In addition, regulates NFAT transcription factors NFATC3 and NFATC4 activities by preventing their nuclear localization, thus inhibiting their transcriptional activities. Decreases TRIM41-mediated degradation of ZSCAN2 thereby stimulating alpha-synuclein/SNCA transcription in neuronal cells. Prevents the E3 ubiquitin-ligase activity of TRIM28 and its interaction with anti-apoptotic BCL2A1, blocking TRIM28 from ubiquitinating BCL2A1.
  • 基因功能參考文獻(xiàn):
    1. TRIM17 promoted the removal of midbodies, remnants of the cell division machinery that are known autophagy targets. PMID: 27562068
    2. NFATc3 interacted in a SUMO-dependent manner with Trim17, an E3 ubiquitin ligase necessary for neuronal apoptosis PMID: 25215946
    3. terf interacts with TRIM44;TRIM44 inhibited ubiquitination of terf, and thus stabilized the protein. PMID: 19358823
  • 亞細(xì)胞定位:
    Cytoplasm. Lysosome.
  • 蛋白家族:
    TRIM/RBCC family
  • 組織特異性:
    Almost exclusively in the testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 13430

    OMIM: 606123

    KEGG: hsa:51127

    STRING: 9606.ENSP00000295033

    UniGene: Hs.121748



主站蜘蛛池模板: 国产做无码视频在线观看浪潮| 免费裸体美女网站| 日本一卡二卡不卡视频查询| 久久久综合九色综合88| 中文字幕精品视频在线看免费| 午夜三级a三级三点在线观看 | 日本极品少妇videossexhd| 巨爆乳无码视频在线观看| 国产精成人品一区| 男女做爰猛烈啪啪吃奶动| 成人18禁深夜福利网站app免费| 欧美性xxxxx极品娇小| 九九九国产精品成人免费视频| 国产午睡沙发被弄醒完整版| 欧美无人区码suv| 国产人妻人伦精品1国产丝袜 | 国产成人精品视频网站| 日本真人边吃奶边做爽动态图| 国产精品毛片在线完整版sab| 精品一区二区三区无码免费直播 | 日本乱人伦在线观看| 男女同房做爰爽免费| 国产+成+人+亚洲欧洲自线| 欧美精品在线观看| 国产精品美女久久久久久| 国产好大好硬好爽免费不卡| 亚洲精品无码mv在线观看网站| 日本在线视频www鲁啊鲁| 成人免费的视频| 国产亚洲精品久久久久9999| 亚洲精品久久久一区| 中出内射颜射骚妇| 亚洲中文字幕永久在线全国| 天下第一社区视频www日本| 夜夜高潮夜夜爽国产伦精品| 狠狠亚洲婷婷综合色香五月排名| 国产精成a品人v在线播放| 国产精品无码dvd在线观看| 夜夜国产亚洲视频香蕉| 日韩精品无码一区二区三区视频| 国产成人高清亚洲一区妲妃|