在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRIM17 Antibody, Biotin conjugated

  • 中文名稱:
    TRIM17兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA897559LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TRIM17 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TRIM17
  • 別名:
    E3 ubiquitin-protein ligase TRIM17 antibody; RBCC antibody; RING finger protein 16 antibody; RING finger protein terf antibody; RNF16 antibody; TERF antibody; Testis RING finger protein antibody; TRI17_HUMAN antibody; TRIM 17 antibody; Trim17 antibody; Tripartite motif containing 17 antibody; Tripartite motif containing protein 17 antibody; Tripartite motif protein 17 antibody; Tripartite motif-containing protein 17 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human E3 ubiquitin-protein ligase TRIM17 protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    E3 ubiquitin ligase that plays important roles in the regulation of neuronal apoptosis, selective autophagy or cell proliferation. Stimulates the degradation of kinetochore ZW10 interacting protein ZWINT in a proteasome-dependent manner, leading to negative regulation of cell proliferation. Inhibits autophagic degradation of diverse known targets while contributing to autophagy of midbodies. Autophagy-inhibitory activity involves MCL1, which TRIM17 assembles into complexes with the key autophagy regulator BECN1. Controls neuronal apoptosis by mediating ubiquitination and degradation of MCL1 to initiate neuronal death. In addition, regulates NFAT transcription factors NFATC3 and NFATC4 activities by preventing their nuclear localization, thus inhibiting their transcriptional activities. Decreases TRIM41-mediated degradation of ZSCAN2 thereby stimulating alpha-synuclein/SNCA transcription in neuronal cells. Prevents the E3 ubiquitin-ligase activity of TRIM28 and its interaction with anti-apoptotic BCL2A1, blocking TRIM28 from ubiquitinating BCL2A1.
  • 基因功能參考文獻(xiàn):
    1. TRIM17 promoted the removal of midbodies, remnants of the cell division machinery that are known autophagy targets. PMID: 27562068
    2. NFATc3 interacted in a SUMO-dependent manner with Trim17, an E3 ubiquitin ligase necessary for neuronal apoptosis PMID: 25215946
    3. terf interacts with TRIM44;TRIM44 inhibited ubiquitination of terf, and thus stabilized the protein. PMID: 19358823
  • 亞細(xì)胞定位:
    Cytoplasm. Lysosome.
  • 蛋白家族:
    TRIM/RBCC family
  • 組織特異性:
    Almost exclusively in the testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 13430

    OMIM: 606123

    KEGG: hsa:51127

    STRING: 9606.ENSP00000295033

    UniGene: Hs.121748



主站蜘蛛池模板: 日本中国内射bbxx| 五月天中文字幕mv在线| 大地资源网中文第五页| 国产99久久九九精品无码| 亚洲丁香婷婷综合久久| 日本又黄又爽gif动态图| 欧美综合自拍亚洲综合图| 国产熟妇勾子乱视频| 精品成人a区在线观看| 无码国产成人久久| 亚洲一卡二卡三卡四卡| 国产亚洲欧美另类一区二区 | 久久人妻av中文字幕| 日日拍夜夜嗷嗷叫国产| 国内精品久久久久影院老司机| 无码帝国www无码专区色综合| 久久人妻av一区二区软件| 国产又爽又黄无码无遮挡在线观看 | 免费看又色又爽又黄的国产软件 | 亚洲精品国产成人99久久6| 免费无码作爱视频| 国产精品高清网站| 色依依av在线| 亚洲国产v高清在线观看| 亚欧日韩欧美网站在线看| 国产亚洲精久久久久久无码苍井空 | 精品免费国偷自产在线视频| 免费无遮挡无码视频在线观看| 成人h视频在线观看| 强迫大乳人妻中文字幕| 国产成人18黄网站| 中文国产成人精品久久不卡| 亚洲国产成人久久综合下载 | 国产精品久久久久久熟妇吹潮软件| 国产精品原创巨作av| 在线综合亚洲欧美网站| 日日日日做夜夜夜夜无码| 国产欧美日韩综合精品一区二区| 欧美 国产 日产 韩国 在线| 99久久国产综合精品1| 第九色区av天堂|